8AQ9
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4IZQ
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4L7Z
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![BU of 4l7z by Molmil](/molmil-images/mine/4l7z) | Crystal Structure of Chloroflexus aurantiacus malyl-CoA lyase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HpcH/HpaI aldolase | 著者 | Zarzycki, J, Kerfeld, C.A. | 登録日 | 2013-06-14 | 公開日 | 2013-12-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | The crystal structures of the tri-functional Chloroflexus aurantiacus and bi-functional Rhodobacter sphaeroides malyl-CoA lyases and comparison with CitE-like superfamily enzymes and malate synthases. Bmc Struct.Biol., 13, 2013
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6Q2J
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![BU of 6q2j by Molmil](/molmil-images/mine/6q2j) | Cryo-EM structure of extracellular dimeric complex of RET/GFRAL/GDF15 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-like, ... | 著者 | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | 登録日 | 2019-08-08 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife, 8, 2019
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4KX3
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4J3Y
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2K14
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![BU of 2k14 by Molmil](/molmil-images/mine/2k14) | Solution structure of the soluble domain of the NfeD protein YuaF from Bacillus subtilis | 分子名称: | YuaF protein | 著者 | Walker, C.A, Hinderhofer, M, Witte, D.J, Boos, W, Moller, H.M. | 登録日 | 2008-02-20 | 公開日 | 2008-08-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the soluble domain of the NfeD protein YuaF from Bacillus subtilis. J.Biomol.Nmr, 42, 2008
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1JDR
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![BU of 1jdr by Molmil](/molmil-images/mine/1jdr) | Crystal Structure of a Proximal Domain Potassium Binding Variant of Cytochrome c Peroxidase | 分子名称: | Cytochrome c Peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Bonagura, C.A, Sundaramoorthy, M, Bhaskar, B, Poulos, T.L. | 登録日 | 2001-06-14 | 公開日 | 2001-06-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The effects of an engineered cation site on the structure, activity, and EPR properties of cytochrome c peroxidase. Biochemistry, 38, 1999
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6PYS
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![BU of 6pys by Molmil](/molmil-images/mine/6pys) | Human PI3Kalpha in complex with Compound 2-10 ((3S)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2H-indol-2-one) | 分子名称: | (3S)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2H-indol-2-one, GLYCEROL, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Lesburg, C.A, Augustin, M.A. | 登録日 | 2019-07-30 | 公開日 | 2019-08-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Design of selective PI3K delta inhibitors using an iterative scaffold-hopping workflow. Bioorg.Med.Chem.Lett., 29, 2019
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6Q1I
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4L7I
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![BU of 4l7i by Molmil](/molmil-images/mine/4l7i) | Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi | 分子名称: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2013-06-13 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
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2F2G
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![BU of 2f2g by Molmil](/molmil-images/mine/2f2g) | X-Ray Structure of Gene Product From Arabidopsis Thaliana AT3G16990 | 分子名称: | 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SEED MATURATION PROTEIN PM36 HOMOLOG, SULFATE ION | 著者 | Wesenberg, G.W, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2005-11-16 | 公開日 | 2005-12-13 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of gene locus At3g16990 from Arabidopsis thaliana Proteins, 57, 2004
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6Q2S
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![BU of 6q2s by Molmil](/molmil-images/mine/6q2s) | Cryo-EM structure of RET/GFRa3/ARTN extracellular complex. The 3D refinement was applied with C2 symmetry. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-3, ... | 著者 | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | 登録日 | 2019-08-08 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife, 8, 2019
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4ITC
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![BU of 4itc by Molmil](/molmil-images/mine/4itc) | Crystal Structure Analysis of the K1 Cleaved Adhesin domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis W83 | 分子名称: | CALCIUM ION, GLYCEROL, GUANIDINE, ... | 著者 | Ganuelas, L.A, Li, N, Hunter, N, Collyer, C.A. | 登録日 | 2013-01-18 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The lysine gingipain adhesin domains from Porphyromonas gingivalis interact with erythrocytes and albumin: Structures correlate to function. Eur J Microbiol Immunol (Bp), 3, 2013
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1CPT
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![BU of 1cpt by Molmil](/molmil-images/mine/1cpt) | CRYSTAL STRUCTURE AND REFINEMENT OF CYTOCHROME P450-TERP AT 2.3 ANGSTROMS RESOLUTION | 分子名称: | CYTOCHROME P450-TERP, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hasemann, C.A, Ravichandran, K.G, Peterson, J.A, Deisenhofer, J. | 登録日 | 1993-11-23 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution. J.Mol.Biol., 236, 1994
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1JBV
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![BU of 1jbv by Molmil](/molmil-images/mine/1jbv) | FPGS-AMPPCP complex | 分子名称: | FOLYLPOLYGLUTAMATE SYNTHASE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Sun, X, Cross, J.A, Bognar, A.L, Baker, E.N, Smith, C.A. | 登録日 | 2001-06-06 | 公開日 | 2001-09-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Folate-binding triggers the activation of folylpolyglutamate synthetase. J.Mol.Biol., 310, 2001
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2F8K
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![BU of 2f8k by Molmil](/molmil-images/mine/2f8k) | Sequence specific recognition of RNA hairpins by the SAM domain of Vts1 | 分子名称: | 5'-R(*UP*AP*AP*UP*CP*UP*UP*UP*GP*AP*CP*AP*GP*AP*UP*U)-3', Protein VTS1 | 著者 | Aviv, T, Lin, Z, Ben-Ari, G, Smibert, C.A, Sicheri, F. | 登録日 | 2005-12-02 | 公開日 | 2006-01-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p. Nat.Struct.Mol.Biol., 13, 2006
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1JIL
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![BU of 1jil by Molmil](/molmil-images/mine/1jil) | Crystal structure of S. aureus TyrRS in complex with SB284485 | 分子名称: | [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]- (3,4,5-TRIHYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YL)- ACETIC ACID, tyrosyl-tRNA synthetase | 著者 | Qiu, X, Janson, C.A, Smith, W.W, Jarvest, R.L. | 登録日 | 2001-07-02 | 公開日 | 2001-10-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors. Protein Sci., 10, 2001
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7ZLV
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![BU of 7zlv by Molmil](/molmil-images/mine/7zlv) | Tail tip of siphophage T5 : central fibre protein pb4 | 分子名称: | Probable central straight fiber | 著者 | Linares, R, Arnaud, C.A, Effantin, G, Epalle, N, Boeri Erba, E, Schoehn, G, Breyton, C. | 登録日 | 2022-04-15 | 公開日 | 2023-02-08 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | 主引用文献 | Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation. Sci Adv, 9, 2023
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4ISZ
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![BU of 4isz by Molmil](/molmil-images/mine/4isz) | RNA ligase RtcB in complex with GTP alphaS and Mn(II) | 分子名称: | GUANOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE, MANGANESE (II) ION, SULFATE ION, ... | 著者 | Desai, K.K, Bingman, C.A, Phillips Jr, G.N, Raines, R.T. | 登録日 | 2013-01-17 | 公開日 | 2013-04-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | Structures of the Noncanonical RNA Ligase RtcB Reveal the Mechanism of Histidine Guanylylation. Biochemistry, 52, 2013
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6PZ7
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![BU of 6pz7 by Molmil](/molmil-images/mine/6pz7) | GH5-4 broad specificity endoglucanase from Clostridium acetobutylicum | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Endoglucanase family 5 | 著者 | Bianchetti, C.M, Bingman, C.A, Fox, B.G. | 登録日 | 2019-07-31 | 公開日 | 2020-08-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | A structural and kinetic survey of GH5_4 endoglucanases reveals determinants of broad substrate specificity and opportunities for biomass hydrolysis. J.Biol.Chem., 295, 2020
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4GIP
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![BU of 4gip by Molmil](/molmil-images/mine/4gip) | Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2 | 著者 | Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A. | 登録日 | 2012-08-08 | 公開日 | 2012-09-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc.Natl.Acad.Sci.USA, 109, 2012
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6Q2O
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![BU of 6q2o by Molmil](/molmil-images/mine/6q2o) | Cryo-EM structure of RET/GFRa2/NRTN extracellular complex. The 3D refinement was applied with C2 symmetry. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha-2, ... | 著者 | Li, J, Shang, G.J, Chen, Y.J, Brautigam, C.A, Liou, J, Zhang, X.W, Bai, X.C. | 登録日 | 2019-08-08 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife, 8, 2019
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2EZM
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4MZ4
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![BU of 4mz4 by Molmil](/molmil-images/mine/4mz4) | Discovery of an Irreversible HCV NS5B Polymerase Inhibitor | 分子名称: | 1-[(2-chloroquinolin-3-yl)methyl]-6-fluoro-5-methyl-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxylic acid, PHOSPHATE ION, RNA-directed RNA polymerase | 著者 | Zeng, Q, Anilkumar, G.N, Rosenblum, S.B, Huang, H.-C, Lesburg, C.A, Jiang, Y, Selyutin, O, Chan, T.-Y, Bennett, F, Chen, K.X, Venkatraman, S, Sannigrahi, M, Velazquez, F, Duca, J.S, Gavalas, S, Huang, Y, Pu, H, Wang, L, Pinto, P, Vibulbhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Li, C, Hesk, D, Gesell, J, Sorota, S, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A. | 登録日 | 2013-09-29 | 公開日 | 2013-12-11 | 最終更新日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Discovery of an irreversible HCV NS5B polymerase inhibitor. Bioorg.Med.Chem.Lett., 23, 2013
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