2BGE
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![BU of 2bge by Molmil](/molmil-images/mine/2bge) | Structure-based design of Protein Tyrosine Phosphatase-1B Inhibitors | 分子名称: | 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE, PROTEIN-TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 1 | 著者 | Black, E, Breed, J, Breeze, A.L, Embrey, K, Garcia, R, Gero, T.W, Godfrey, L, Kenny, P.W, Morley, A.D, Minshull, C.A, Pannifer, A.D, Read, J, Rees, A, Russell, D.J, Toader, D, Tucker, J. | 登録日 | 2004-12-21 | 公開日 | 2005-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors Bioorg.Med.Chem.Lett., 15, 2005
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2BGD
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![BU of 2bgd by Molmil](/molmil-images/mine/2bgd) | Structure-based design of Protein Tyrosine Phosphatase-1B Inhibitors | 分子名称: | 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE, CHLORIDE ION, PHOSPHATE ION, ... | 著者 | Black, E, Breed, J, Breeze, A.L, Embrey, K, Garcia, R, Gero, T.W, Godfrey, L, Kenny, P.W, Morley, A.D, Minshull, C.A, Pannifer, A.D, Read, J, Rees, A, Russell, D.J, Toader, D, Tucker, J. | 登録日 | 2004-12-21 | 公開日 | 2005-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors Bioorg.Med.Chem.Lett., 15, 2005
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6MZU
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2C1Z
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![BU of 2c1z by Molmil](/molmil-images/mine/2c1z) | Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification | 分子名称: | 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE | 著者 | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | 登録日 | 2005-09-22 | 公開日 | 2006-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification. Embo J., 25, 2006
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2C1X
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![BU of 2c1x by Molmil](/molmil-images/mine/2c1x) | Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | 著者 | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | 登録日 | 2005-09-22 | 公開日 | 2006-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification. Embo J., 25, 2006
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1RP4
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![BU of 1rp4 by Molmil](/molmil-images/mine/1rp4) | Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell | 分子名称: | 1-ETHYL-PYRROLIDINE-2,5-DIONE, CADMIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Gross, E, Kastner, D.B, Kaiser, C.A, Fass, D. | 登録日 | 2003-12-03 | 公開日 | 2004-06-08 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of ero1p, source of disulfide bonds for oxidative protein folding in the cell. Cell(Cambridge,Mass.), 117, 2004
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1A3E
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![BU of 1a3e by Molmil](/molmil-images/mine/1a3e) | COMPLEX OF HUMAN ALPHA-THROMBIN WITH THE BIFUNCTIONAL BORONATE INHIBITOR BOROLOG2 | 分子名称: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), BOROLOG2, ... | 著者 | Skordalakes, E, Elgendy, S, Goodwin, C.A, Green, D, Scullly, M.F, Kakkar, V.V, Freyssinet, J.M, Dodson, G, Deadman, J. | 登録日 | 1998-01-21 | 公開日 | 1998-06-03 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide. Biochemistry, 37, 1998
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1AGC
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![BU of 1agc by Molmil](/molmil-images/mine/1agc) | ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYQL-7Q MUTATION) | 分子名称: | B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYQL - 7Q MUTATION) | 著者 | Reid, S.W, Mcadam, S, Smith, K.J, Klenerman, P, O'Callaghan, C.A, Harlos, K, Jakobsen, B.K, Mcmichael, A.J, Bell, J, Stuart, D.I, Jones, E.Y. | 登録日 | 1997-03-24 | 公開日 | 1997-06-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J.Exp.Med., 184, 1996
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6NER
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![BU of 6ner by Molmil](/molmil-images/mine/6ner) | Synthetic Haliangium ochraceum BMC shell | 分子名称: | BMC-H tandem fusion protein, SULFATE ION | 著者 | Sutter, M, McGuire, S, Aussignargues, C, Kerfeld, C.A. | 登録日 | 2018-12-18 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Structural Characterization of a Synthetic Tandem-Domain Bacterial Microcompartment Shell Protein Capable of Forming Icosahedral Shell Assemblies. ACS Synth Biol, 8, 2019
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2W2K
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![BU of 2w2k by Molmil](/molmil-images/mine/2w2k) | Crystal structure of the apo forms of Rhodotorula graminis D- mandelate dehydrogenase at 1.8A. | 分子名称: | D-MANDELATE DEHYDROGENASE | 著者 | Vachieri, S.G, Cole, A.R, Bagneris, C, Baker, D.P, Fewson, C.A, Basak, A.K. | 登録日 | 2008-11-02 | 公開日 | 2009-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase To be Published
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3PI4
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![BU of 3pi4 by Molmil](/molmil-images/mine/3pi4) | Crystallographic Structure of HbII-oxy from Lucina pectinata at pH 4.0 | 分子名称: | Hemoglobin II, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Gavira, J.A, Nieves-Marrero, C.A, Ruiz-Martinez, C.R, Estremera-Andujar, R.A, Lopez-Garriga, J, Garcia-Ruiz, J.M. | 登録日 | 2010-11-05 | 公開日 | 2011-11-09 | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | 主引用文献 | pH-dependence crystallographic studies of the oxygen carrier hemoglobin II from Lucina pectinata To be Published
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2WFQ
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![BU of 2wfq by Molmil](/molmil-images/mine/2wfq) | Crystal structure of the N-terminal signalling domain of human Dhh without calcium | 分子名称: | DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ZINC ION | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-14 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2C9Z
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![BU of 2c9z by Molmil](/molmil-images/mine/2c9z) | Structure and activity of a flavonoid 3-0 glucosyltransferase reveals the basis for plant natural product modification | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, UDP GLUCOSE:FLAVONOID 3-O-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | 著者 | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | 登録日 | 2005-12-15 | 公開日 | 2006-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification. Embo J., 25, 2006
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2W43
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![BU of 2w43 by Molmil](/molmil-images/mine/2w43) | Structure of L-haloacid dehalogenase from S. tokodaii | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HYPOTHETICAL 2-HALOALKANOIC ACID DEHALOGENASE, PHOSPHATE ION | 著者 | Rye, C.A, Isupov, M.N, Lebedev, A.A, Littlechild, J.A. | 登録日 | 2008-11-21 | 公開日 | 2008-12-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Biochemical and Structural Studies of a L-Haloacid Dehalogenase from the Thermophilic Archaeon Sulfolobus Tokodaii. Extremophiles, 13, 2009
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5OAM
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![BU of 5oam by Molmil](/molmil-images/mine/5oam) | Molecular basis of human kinesin-8 function and inhibition | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF18A, ... | 著者 | Locke, J, Joseph, A.P, Topf, M, Moores, C.A. | 登録日 | 2017-06-23 | 公開日 | 2017-10-25 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structural basis of human kinesin-8 function and inhibition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1AOL
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![BU of 1aol by Molmil](/molmil-images/mine/1aol) | FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GP70, ZINC ION | 著者 | Fass, D, Davey, R.A, Hamson, C.A, Kim, P.S, Cunningham, J.M, Berger, J.M. | 登録日 | 1997-07-08 | 公開日 | 1997-10-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution. Science, 277, 1997
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6N6U
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2WG4
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![BU of 2wg4 by Molmil](/molmil-images/mine/2wg4) | Crystal structure of the complex between human hedgehog-interacting protein HIP and sonic hedgehog without calcium | 分子名称: | HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, SONIC HEDGEHOG PROTEIN N-PRODUCT, ... | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-15 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2W3K
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![BU of 2w3k by Molmil](/molmil-images/mine/2w3k) | Crystal Structure of FXa in complex with 4,4-disubstituted pyrrolidine-1,2-dicarboxamide inhibitor 1 | 分子名称: | (2R,4S)-N^1^-(4-chlorophenyl)-N^2^-[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]-4-hydroxy-4-phenylpyrrolidine-1,2-dicarboxamide, CALCIUM ION, COAGULATION FACTOR X, ... | 著者 | Zhang, E, Mochalkin, I, Casimiro-Garcia, A, Van Huis, C.A. | 登録日 | 2008-11-12 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Exploration of 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamides as Potent, Orally Active Factor Xa Inhibitors with Extended Duration of Action. Bioorg.Med.Chem., 17, 2009
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2WFX
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![BU of 2wfx by Molmil](/molmil-images/mine/2wfx) | Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium | 分子名称: | CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ... | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-15 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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1AYV
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![BU of 1ayv by Molmil](/molmil-images/mine/1ayv) | CRYSTAL STRUCTURE OF CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT THIAZOLHYDRAZIDE INHIBITOR | 分子名称: | CATHEPSIN K, N-[2-[1-(N-BENZYLOXYCARBONYLAMINO)-3-METHYLBUTYL]THIAZOL-4-YLCARBONYL]-N'-(BENZYLOXYCARBONYL-L-LEUCINYL)HYDRAZIDE | 著者 | Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S. | 登録日 | 1997-11-10 | 公開日 | 1998-11-25 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design of potent and selective human cathepsin K inhibitors that span the active site. Proc.Natl.Acad.Sci.USA, 94, 1997
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1T8K
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6NC3
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![BU of 6nc3 by Molmil](/molmil-images/mine/6nc3) | AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ... | 著者 | Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B. | 登録日 | 2018-12-10 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
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1TH8
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![BU of 1th8 by Molmil](/molmil-images/mine/1th8) | Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form II | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ... | 著者 | Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigian, J, Leon, F, Darst, S.A, Campbell, E.A. | 登録日 | 2004-06-01 | 公開日 | 2004-06-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA. J.Mol.Biol., 340, 2004
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1SYV
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![BU of 1syv by Molmil](/molmil-images/mine/1syv) | HLA-B*4405 complexed to the dominant self ligand EEFGRAYGF | 分子名称: | Beta-2-microglobulin, MHC class I antigen, major histocompatibility complex, ... | 著者 | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | 登録日 | 2004-04-02 | 公開日 | 2004-10-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion J.Exp.Med., 200, 2004
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