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PDB: 9 件
7ZAU
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BU of 7zau by Molmil
Fascin-1 in complex with Nb 3E11
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fascin, ...
著者Burgess, S.G, Bayliss, R.
登録日2022-03-22
公開日2023-09-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation.
Open Biology, 14, 2024
5L8J
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BU of 5l8j by Molmil
Aurora-A kinase domain in complex with vNAR-D01 S93R
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ...
著者Burgess, S.G, Bayliss, R.
登録日2016-06-08
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.
Open Biology, 6, 2016
5L8L
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BU of 5l8l by Molmil
Aurora-A kinase domain in complex with vNAR-D01 (crystal form 1)
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ...
著者Burgess, S.G, Bayliss, R.
登録日2016-06-08
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.
Open Biology, 6, 2016
6I2U
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BU of 6i2u by Molmil
Aurora-A kinase domain in complex with Coenzyme A
分子名称: Aurora kinase A, COENZYME A, DI(HYDROXYETHYL)ETHER, ...
著者Burgess, S.G, Bayliss, R.
登録日2018-11-02
公開日2019-10-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Covalent Aurora A regulation by the metabolic integrator coenzyme A.
Redox Biol, 28, 2019
5L8K
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BU of 5l8k by Molmil
Aurora-A kinase domain in complex with vNAR-D01 (crystal form 2)
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ...
著者Burgess, S.G, Bayliss, R.
登録日2016-06-08
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.
Open Biology, 6, 2016
4CEG
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BU of 4ceg by Molmil
Crystal structure of Aurora A 122-403 C290A, C393A bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, CHLORIDE ION, ...
著者Burgess, S.G, Bayliss, R.
登録日2013-11-11
公開日2015-01-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Structure of C290A:C393A Aurora a Provides Structural Insights Into Kinase Regulation.
Acta Crystallogr.,Sect.F, 71, 2015
5ODT
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BU of 5odt by Molmil
Aurora-A in complex with TACC3
分子名称: ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, GLYCEROL, ...
著者Burgess, S.G, Bayliss, R.
登録日2017-07-06
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.021 Å)
主引用文献Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic alpha-helix.
EMBO J., 37, 2018
5G1X
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BU of 5g1x by Molmil
Crystal structure of Aurora-A kinase in complex with N-Myc
分子名称: ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, MAGNESIUM ION, ...
著者Richards, M.W, Burgess, S.G, Bayliss, R.
登録日2016-03-31
公開日2016-11-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural Basis of N-Myc Binding by Aurora-A and its Destabilization by Kinase Inhibitors
Proc.Natl.Acad.Sci.USA, 113, 2016
5ORL
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BU of 5orl by Molmil
Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment
分子名称: ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, CHLORIDE ION, ...
著者McIntyre, P.J, Collins, P.M, Vrzal, L, Birchall, K, Arnold, L.H, Mpamhanga, C, Coombs, P.J, Burgess, S.G, Richards, M.W, Winter, A, Veverka, V, von Delft, F, Merritt, A, Bayliss, R.
登録日2017-08-16
公開日2017-11-01
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017

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件を2024-07-17に公開中

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