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PDB: 48 件

8GKK
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Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6
分子名称: MUC16 antibody AR9.6 heavy chain, MUC16 antibody AR9.6 light chain, SULFATE ION
著者Brooks, C.L, Murray, B.
登録日2023-03-19
公開日2024-03-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the MUC16 Specific Antibody AR9.6
To Be Published
4U9C
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STRUCTURE OF THE LBPB N-LOBE FROM NEISSERIA MENINGITIDIS
分子名称: Lactoferrin-binding protein B
著者Brooks, C.L, Arutyunova, E, Lemieux, M.J.
登録日2014-08-05
公開日2014-10-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献The structure of lactoferrin-binding protein B from Neisseria meningitidis suggests roles in iron acquisition and neutralization of host defences.
Acta Crystallogr.,Sect.F, 70, 2014
6DBD
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Crystal Structure of VHH R326
分子名称: ACETATE ION, SODIUM ION, nanobody VHH R326
著者Brooks, C.L, Toride King, M, Huh, I.
登録日2018-05-03
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.755 Å)
主引用文献Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes.
J. Biol. Chem., 293, 2018
6DBA
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Crystal Structure of VHH R303
分子名称: nanobody VHH R303
著者Brooks, C.L, Toride King, M, Huh, I.
登録日2018-05-02
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes.
J. Biol. Chem., 293, 2018
6DBE
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Crystal Structure of VHH R330
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, nanobody VHH R303
著者Brooks, C.L, Toride King, M, Huh, I.
登録日2018-05-03
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes.
J. Biol. Chem., 293, 2018
6DBF
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Crystal Structure of VHH R303 in complex with InlB-LRR
分子名称: InlB specific VHH R303, Listeria virulence factor InlB
著者Brooks, C.L, Toride King, M, Huh, I.
登録日2018-05-03
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes.
J. Biol. Chem., 293, 2018
6DBG
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Crystal Structure of VHH R303 in complex with InlB-LRR-IR
分子名称: Internalin B, VHH R303
著者Brooks, C.L, Toride King, M, Huh, I.
登録日2018-05-03
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural basis of VHH-mediated neutralization of the food-borne pathogenListeria monocytogenes.
J. Biol. Chem., 293, 2018
6DYX
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Structure of VHH R419 isolated from a pre-immune phage display library
分子名称: ACETATE ION, SULFATE ION, VHH R419
著者Brooks, C.L.
登録日2018-07-02
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of a VHH isolated from a naive phage display library.
BMC Res Notes, 12, 2019
8GKJ
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Crystal Structure of the Murine MUC16 Specific Antibody AR9.6
分子名称: MUC16 antibody AR9.6 heavy chain, MUC16 antibody AR9.6 light chain
著者Brooks, C.L, Aguilar, E.N.
登録日2023-03-19
公開日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Murine MUC16 Specific Antibody AR9.6
To Be Published
8GKL
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Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6
分子名称: MUC16 antibody AR9.6 Fab heavy chain, MUC16 antibody AR9.6 Fab light chain, Mucin-16
著者Brooks, C.L, Aguilar, E.N.
登録日2023-03-19
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the MUC16 Specific Antibody AR9.6
To Be Published
7SA9
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Human MUC16 SEA5 Domain
分子名称: Mucin-16
著者Brooks, C.L, White, B.
登録日2021-09-22
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor marker.
Proteins, 90, 2022
5T78
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Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, Fab Fragment - AR20.5 - Heavy chain, Fab fragment AR20.5 - Light Chain, ...
著者Brooks, C.L, Movahedin, M.
登録日2016-09-02
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology, 27, 2017
5T6P
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Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
分子名称: Fab Fragment - Heavy Chain, Fab fragment AR20.5 - Light Chain, MUC1 Peptide Fragment
著者Brooks, C.L, Movahedin, M.
登録日2016-09-01
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology, 27, 2017
3ODJ
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BU of 3odj by Molmil
Crystal structure of H. influenzae rhomboid GlpG with disordered loop 4, helix 5 and loop 5
分子名称: Rhomboid protease glpG
著者Brooks, C.L, Lazareno-Saez, C, Lamoureux, J.S, Mak, M.W, Lemieux, M.J.
登録日2010-08-11
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Insights into Substrate Gating in H. influenzae Rhomboid.
J.Mol.Biol., 407, 2011
4HGW
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Crystal structure of S25-2 in complex with a 5,6-dehydro-Kdo disaccharide
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3,5-dideoxy-alpha-D-threo-oct-5-en-2-ulopyranosidonic acid, Antibody Fab fragment, heavy chain, ...
著者Brooks, C.L, Evans, S.V.
登録日2012-10-08
公開日2013-01-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide.
Acta Crystallogr.,Sect.F, 69, 2013
3DV4
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Crystal structure of SAG506-01, tetragonal, crystal 1
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ...
著者Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V.
登録日2008-07-18
公開日2008-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
3DV6
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BU of 3dv6 by Molmil
Crystal structure of SAG506-01, tetragonal, crystal 2
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ...
著者Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V.
登録日2008-07-18
公開日2008-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
3DUS
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BU of 3dus by Molmil
Crystal structure of SAG506-01, orthorhombic, twinned, crystal 1
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ...
著者Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V.
登録日2008-07-17
公開日2008-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
3DUR
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BU of 3dur by Molmil
Crystal structure of SAG173-04
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ...
著者Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V.
登録日2008-07-17
公開日2008-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
3DUU
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BU of 3duu by Molmil
Crystal structure of SAG506-01, orthorhombic, twinned, crystal 2
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ...
著者Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V.
登録日2008-07-17
公開日2008-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
3BPC
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BU of 3bpc by Molmil
co-crystal structure of S25-2 Fab in complex with 5-deoxy-4-epi-2,3-dehydro Kdo (4.8) Kdo
分子名称: 3,4,5-trideoxy-alpha-D-erythro-oct-3-en-2-ulopyranosonic acid-(2-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ...
著者Brooks, C.L, Evans, S.V.
登録日2007-12-18
公開日2009-01-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
J.Mol.Biol., 377, 2008
2R2H
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BU of 2r2h by Molmil
Structure of S25-2 in Complex with Ko
分子名称: Fab, antibody fragment (IgG1k), heavy chain, ...
著者Brooks, C.L, Evans, S.V.
登録日2007-08-25
公開日2008-12-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
J.Mol.Biol., 377, 2008
2R2E
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BU of 2r2e by Molmil
Crystal structure of S25-2 Fab in complex with Kdo analogues
分子名称: Fab, antibody fragment (IgG1k), heavy chain, ...
著者Brooks, C.L, Evans, S.V.
登録日2007-08-24
公開日2008-12-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
J.Mol.Biol., 377, 2008
2R23
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Crystal structure of S25-2 Fab in complex with Kdo analogues
分子名称: D-glycero-alpha-D-talo-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ...
著者Brooks, C.L, Evans, S.V.
登録日2007-08-24
公開日2008-12-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
J.Mol.Biol., 377, 2008
2R1Y
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BU of 2r1y by Molmil
Crystal structure of S25-2 Fab in complex with Kdo analogues
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-octos-2-ulopyranoside, Fab, antibody fragment (IgG1k), ...
著者Brooks, C.L, Evans, S.V.
登録日2007-08-23
公開日2008-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
J.Mol.Biol., 377, 2008

 

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