2CMY
 
 | | Crystal complex between bovine trypsin and Veronica hederifolia trypsin inhibitor | | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, GLYCEROL, ... | | Authors: | Conners, R, Yardley, J.L, Konarev, A, Shewry, P, Brady, R.L. | | Deposit date: | 2006-05-16 | | Release date: | 2007-05-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica Hederifolia L.).
J.Biol.Chem., 282, 2007
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1EB2
 | | Trypsin inhibitor complex (BPO) | | Descriptor: | 3-[(Z)-AMINO(IMINO)METHYL]-N-[2-(4-BENZOYL-1-PIPERIDINYL)-2-OXO-1-PHENYLETHYL]BENZAMIDE, CALCIUM ION, SULFATE ION, ... | | Authors: | Wilkinson, K.W, Young, S.C, Liebeschuetz, J.W, Brady, R.L. | | Deposit date: | 2001-07-18 | | Release date: | 2002-02-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Pro_Select: Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors
J.Med.Chem., 45, 2002
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4H8F
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4H8G
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4H8O
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4H8L
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4H8M
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4H7R
 | | Crystal structure of a parallel 4-helix coiled coil CC-Hex-II | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, CC-Hex-II, GLYCEROL | | Authors: | Chi, B, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2012-09-20 | | Release date: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | TBA
To be Published
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4IMM
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4KVT
 | | Crystal structure of a 6-helix coiled coil CC-Hex-L24C | | Descriptor: | 6-helix coiled coil CC-Hex-L24C peptide | | Authors: | Burton, A.J, Agnew, C, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2013-05-23 | | Release date: | 2013-08-21 | | Last modified: | 2013-09-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly.
J.Am.Chem.Soc., 135, 2013
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4KVV
 | | Crystal structure of an alkylated Cys mutant of CC-Hex | | Descriptor: | 6-HELIX COILED COIL CC-HEX-L24C PEPTIDE with an alkylated Cys mutation | | Authors: | Burton, A.J, Agnew, C, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2013-05-23 | | Release date: | 2013-08-21 | | Last modified: | 2013-09-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly.
J.Am.Chem.Soc., 135, 2013
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4KVU
 | | Crystal structure of a 6-helix coiled coil CC-Hex-L17C-W224BF | | Descriptor: | 6-helix coiled coil CC-Hex-L17C-W224BF, GLYCEROL | | Authors: | Burton, A.J, Agnew, C, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2013-05-23 | | Release date: | 2013-08-21 | | Last modified: | 2013-09-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly.
J.Am.Chem.Soc., 135, 2013
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3NTN
 | | Crystal Structure of UspA1 head and neck domain from Moraxella catarrhalis | | Descriptor: | CHLORIDE ION, NICKEL (II) ION, SULFATE ION, ... | | Authors: | Conners, R, Zaccai, N, Agnew, C, Burton, N, Brady, R.L. | | Deposit date: | 2010-07-05 | | Release date: | 2011-07-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3PR7
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3R3K
 | | Crystal structure of a parallel 6-helix coiled coil | | Descriptor: | 1,2-ETHANEDIOL, CChex-Phi22 helix, CHLORIDE ION, ... | | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | | Deposit date: | 2011-03-16 | | Release date: | 2011-11-16 | | Last modified: | 2011-11-30 | | Method: | X-RAY DIFFRACTION (2.2009 Å) | | Cite: | A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
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3R46
 | | Crystal structure of a parallel 6-helix coiled coil CC-hex-D24 | | Descriptor: | CHLORIDE ION, GLYCEROL, SODIUM ION, ... | | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | | Deposit date: | 2011-03-17 | | Release date: | 2011-11-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.751 Å) | | Cite: | A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
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3R4A
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3R48
 | | Crystal structure of a hetero-hexamer coiled coil | | Descriptor: | GLYCEROL, coiled coil helix W22-L24H, coiled coil helix Y15-L24D | | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | | Deposit date: | 2011-03-17 | | Release date: | 2011-11-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.0011 Å) | | Cite: | A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
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3R4H
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3RA3
 | | Crystal structure of a section of a de novo design gigaDalton protein fibre | | Descriptor: | SODIUM ION, p1c, p2f | | Authors: | Zaccai, N.R, Sharp, T.H, Bruning, M, Woolfson, D.N, Brady, R.L. | | Deposit date: | 2011-03-27 | | Release date: | 2012-08-08 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design
Proc.Natl.Acad.Sci.USA, 109, 2012
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3R8Q
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3R9B
 | | Crystal structure of Mycobacterium smegmatis CYP164A2 in ligand free state | | Descriptor: | 1,2-ETHANEDIOL, CYTOCHROME P450 164A2, DODECANE, ... | | Authors: | Agnew, C.R.J, Warrilow, A.G.S, Kelly, S.L, Brady, R.L. | | Deposit date: | 2011-03-25 | | Release date: | 2012-04-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | An enlarged, adaptable active site in CYP164 family P450 enzymes, the sole P450 in Mycobacterium leprae.
Antimicrob.Agents Chemother., 56, 2012
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3R47
 | | Crystal structure of a 6-helix coiled coil CC-hex-H24 | | Descriptor: | BROMIDE ION, coiled coil helix L24H | | Authors: | Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L. | | Deposit date: | 2011-03-17 | | Release date: | 2011-11-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5002 Å) | | Cite: | A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
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3R9C
 | | Crystal structure of Mycobacterium smegmatis CYP164A2 with Econazole bound | | Descriptor: | 1,2-ETHANEDIOL, 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Cytochrome P450 164A2, ... | | Authors: | Agnew, C.R.J, Kelly, S.L, Brady, R.L. | | Deposit date: | 2011-03-25 | | Release date: | 2012-03-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | An enlarged, adaptable active site in CYP164 family P450 enzymes, the sole P450 in Mycobacterium leprae.
Antimicrob.Agents Chemother., 56, 2012
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1SFI
 | | High resolution structure of a potent, cyclic protease inhibitor from sunflower seeds | | Descriptor: | CALCIUM ION, SULFATE ION, TRYPSIN, ... | | Authors: | Luckett, S, Garcia, R.S, Barker, J.J, Konarev, A.V, Shewry, P, Clarke, A.R, Brady, R.L. | | Deposit date: | 1998-12-16 | | Release date: | 1999-07-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds.
J.Mol.Biol., 290, 1999
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