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PDB: 65 results

8CUD
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BU of 8cud by Molmil
Human excitatory amino acid transporter 3 (EAAT3) protomer in an outward facing apo state in 300 mM KCl
Descriptor: Excitatory amino acid transporter 3
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
8CUJ
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BU of 8cuj by Molmil
Human excitatory amino acid transporter 3 (EAAT3) protomer in an outward facing apo state in 150 mM NMDG-Cl
Descriptor: Excitatory amino acid transporter 3
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
8CUA
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BU of 8cua by Molmil
Human excitatory amino acid transporter 3 (EAAT3) with bound potassium in an intermediate outward facing state
Descriptor: Excitatory amino acid transporter 3, MERCURY (II) ION, POTASSIUM ION
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
7RCP
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BU of 7rcp by Molmil
GltPh mutant (S279E/D405N) in complex with aspartate and sodium ions
Descriptor: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Reddy, K.D, Boudker, O.
Deposit date:2021-07-07
Release date:2022-04-20
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:The archaeal glutamate transporter homologue GltPh shows heterogeneous substrate binding.
J.Gen.Physiol., 154, 2022
7UGX
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BU of 7ugx by Molmil
Asp-bound GltPh RSMR mutant in IFS-B1 state
Descriptor: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Huang, Y, Boudker, O.
Deposit date:2022-03-25
Release date:2023-03-29
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19 F NMR and Cryo-EM.
J.Am.Chem.Soc., 145, 2023
7UH6
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BU of 7uh6 by Molmil
Asp-bound GltPh RSMR mutant in IFS-B2 state
Descriptor: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Huang, Y, Boudker, O.
Deposit date:2022-03-25
Release date:2023-03-29
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM
J.Am.Chem.Soc., 145, 2023
7UGJ
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BU of 7ugj by Molmil
TBOA-bound GltPh RSMR mutant in OFS state
Descriptor: (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Huang, Y, Boudker, O.
Deposit date:2022-03-24
Release date:2023-03-29
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM
J.Am.Chem.Soc., 145, 2023
7UGV
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BU of 7ugv by Molmil
Asp-bound GltPh RSMR mutant in IFS-A2 state
Descriptor: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Huang, Y, Boudker, O.
Deposit date:2022-03-25
Release date:2023-03-29
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19 F NMR and Cryo-EM.
J.Am.Chem.Soc., 145, 2023
7UH3
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BU of 7uh3 by Molmil
Asp-bound GltPh RSMR mutant in iOFS state
Descriptor: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Huang, Y, Boudker, O.
Deposit date:2022-03-25
Release date:2023-03-29
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM
J.Am.Chem.Soc., 145, 2023
7UGD
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BU of 7ugd by Molmil
Asp-bound GltPh RSMR mutant in IFS-A1 state
Descriptor: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Huang, Y, Boudker, O.
Deposit date:2022-03-24
Release date:2023-03-29
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM
J.Am.Chem.Soc., 145, 2023
6X15
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BU of 6x15 by Molmil
Inward-facing state of the glutamate transporter homologue GltPh in complex with L-aspartate and sodium ions
Descriptor: ASPARTIC ACID, Glutamate transporter homologue GltPh, MERCURY (II) ION, ...
Authors:Wang, X, Boudker, O.
Deposit date:2020-05-18
Release date:2020-11-18
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters.
Elife, 9, 2020
8CV3
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BU of 8cv3 by Molmil
Human Excitatory excitatory amino acid transporter 3 (EAAT3) protomer at in an intermediate outward facing sodium-bound state
Descriptor: Excitatory amino acid transporter 3, SODIUM ION
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
8CTD
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BU of 8ctd by Molmil
Human excitatory amino acid transporter 3 (EAAT3) protomer with bound glutamate in an outward facing state
Descriptor: Excitatory amino acid transporter 3, GLUTAMIC ACID, MERCURY (II) ION, ...
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-14
Release date:2023-05-10
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
8CV2
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BU of 8cv2 by Molmil
Human excitatory amino acid transporter 3 (EAAT3) in an outward facing sodium-bound state
Descriptor: Excitatory amino acid transporter 3, SODIUM ION
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
8CUI
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BU of 8cui by Molmil
Human excitatory amino acid transporter 3 (EAAT3) in an intermediate outward facing apo state
Descriptor: Excitatory amino acid transporter 3
Authors:Qiu, B, Boudker, O.
Deposit date:2022-05-17
Release date:2023-05-10
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Symport and antiport mechanisms of human glutamate transporters.
Nat Commun, 14, 2023
6X17
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BU of 6x17 by Molmil
Outward-facing state of the glutamate transporter homologue GltPh in complex with TBOA
Descriptor: Glutamate transporter homologue GltPh, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
Authors:Wang, X, Boudker, O.
Deposit date:2020-05-18
Release date:2020-11-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters.
Elife, 9, 2020
6X3F
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BU of 6x3f by Molmil
hEAAT3-IFS-Apo
Descriptor: CHOLINE ION, Excitatory amino acid transporter 3
Authors:Qiu, B, Matthies, D, Boudker, O.
Deposit date:2020-05-21
Release date:2021-03-17
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport.
Sci Adv, 7, 2021
7RNX
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BU of 7rnx by Molmil
CLC-ec1 at pH 7.5 100mM Cl Swap
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-07-30
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RP6
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BU of 7rp6 by Molmil
CLC-ec1 at pH 4.5 100 mM NaGluconate Swap
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-03
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RO0
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BU of 7ro0 by Molmil
CLC-ec1 at pH 7.5 100 mM NaGluconate Swap
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-07-30
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RSB
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BU of 7rsb by Molmil
CLC-ec1 at pH 4.5 100 mM NaGluconate Turn
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-11
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RP5
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BU of 7rp5 by Molmil
CLC-ec1 at pH 4.5 100mM Cl Turn
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-03
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7RQ7
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BU of 7rq7 by Molmil
CLC-ec1 at pH 4.5 100mM Cl TWIST2
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-08-05
Release date:2022-11-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
6BYM
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BU of 6bym by Molmil
Crystal structure of the sterol-bound second StART domain of yeast Lam4
Descriptor: 25-HYDROXYCHOLESTEROL, Sterol-binding protein
Authors:Jentsch, J.A, Kiburu, I.N, Wu, J, Pandey, K, Boudker, O, Menon, A.K.
Deposit date:2017-12-20
Release date:2018-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of sterol binding and transport by a yeast StARkin domain.
J. Biol. Chem., 293, 2018
6BYD
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BU of 6byd by Molmil
Crystal structure of the second StART domain of yeast Lam4
Descriptor: Membrane-anchored lipid-binding protein LAM4
Authors:Jentsch, J.A, Kiburu, I.N, Wu, J, Pandey, K, Boudker, O, Menon, A.K.
Deposit date:2017-12-20
Release date:2018-01-31
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Structural basis of sterol binding and transport by a yeast StARkin domain.
J. Biol. Chem., 293, 2018

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