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PDB: 38 件

5AIP
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Crystal structure of NadR in complex with 4-hydroxyphenylacetate
分子名称: 4-HYDROXYPHENYLACETATE, TRANSCRIPTIONAL REGULATOR, MARR FAMILY
著者Liguori, A, Malito, E, Bottomley, M.J.
登録日2015-02-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
Plos Pathog., 12, 2016
1OQJ
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BU of 1oqj by Molmil
Crystal structure of the SAND domain from glucocorticoid modulatory element binding protein-1 (GMEB1)
分子名称: Glucocorticoid Modulatory Element Binding protein-1, ZINC ION
著者Surdo, P.L, Bottomley, M.J, Sattler, M, Scheffzek, K.
登録日2003-03-10
公開日2003-11-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions
MOL.ENDOCRINOL., 17, 2003
3P5B
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BU of 3p5b by Molmil
The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation
分子名称: CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9
著者Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A.
登録日2010-10-08
公開日2011-10-26
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
3P5C
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BU of 3p5c by Molmil
The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation
分子名称: CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9
著者Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A.
登録日2010-10-08
公開日2011-10-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
4BIH
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BU of 4bih by Molmil
Crystal structure of the conserved staphylococcal antigen 1A, Csa1A
分子名称: CALCIUM ION, UNCHARACTERIZED LIPOPROTEIN SAOUHSC_00053
著者Malito, E, Bottomley, M.J, Spraggon, G, Schluepen, C, Liberatori, S.
登録日2013-04-10
公開日2013-08-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.459 Å)
主引用文献Mining the Bacterial Unknown Proteome: Identification and Characterization of a Novel Family of Highly Conserved Protective Antigens in Staphylococcus Aureus
Biochem.J., 455, 2013
4BIG
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BU of 4big by Molmil
Crystal structure of the conserved staphylococcal antigen 1B, Csa1B
分子名称: UNCHARACTERIZED LIPOPROTEIN SAOUHSC_00053
著者Malito, E, Bottomley, M.J, Schluepen, C, Liberatori, S.
登録日2013-04-10
公開日2013-08-07
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.274 Å)
主引用文献Mining the Bacterial Unknown Proteome: Identification and Characterization of a Novel Family of Highly Conserved Protective Antigens in Staphylococcus Aureus
Biochem.J., 455, 2013
4B8Y
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Ferrichrome-bound FhuD2
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, FE (III) ION, ...
著者Malito, E, Bottomley, M.J, Spraggon, G.
登録日2012-08-31
公開日2012-11-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Characterization of the Staphylococcus Aureus Virulence Factor and Vaccine Candidate Fhud2.
Biochem.J., 449, 2013
4CJD
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BU of 4cjd by Molmil
Crystal structure of Neisseria meningitidis trimeric autotransporter and vaccine antigen NadA
分子名称: IODIDE ION, NADA
著者Malito, E, Biancucci, M, Spraggon, G, Bottomley, M.J.
登録日2013-12-19
公開日2014-11-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.056 Å)
主引用文献Structure of the Meningococcal Vaccine Antigen Nada and Epitope Mapping of a Bactericidal Antibody.
Proc.Natl.Acad.Sci.USA, 111, 2014
4DMW
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BU of 4dmw by Molmil
Crystal structure of the GT domain of Clostridium difficile toxin A (TcdA) in complex with UDP and Manganese
分子名称: MANGANESE (II) ION, Toxin A, URIDINE-5'-DIPHOSPHATE
著者Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Scarselli, M, Maione, D, Martinelli, M.
登録日2012-02-08
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release.
Febs J., 279, 2012
4DMV
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BU of 4dmv by Molmil
Crystal structure of the GT domain of Clostridium difficile Toxin A
分子名称: Toxin A
著者Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Maione, D, Scarselli, M, Martinelli, M.
登録日2012-02-08
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release.
Febs J., 279, 2012
2YPV
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BU of 2ypv by Molmil
Crystal structure of the Meningococcal vaccine antigen factor H binding protein in complex with a bactericidal antibody
分子名称: 1,2-ETHANEDIOL, FAB 12C1, LIPOPROTEIN
著者Malito, E, Veggi, D, Bottomley, M.J.
登録日2012-11-01
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Defining a Protective Epitope on Factor H Binding Protein, a Key Meningococcal Virulence Factor and Vaccine Antigen.
Proc.Natl.Acad.Sci.USA, 110, 2013
2Y7S
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BU of 2y7s by Molmil
Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
分子名称: FACTOR H BINDING PROTEIN
著者Malito, E, Spraggon, G, Bottomley, M.J.
登録日2011-02-01
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011
4D7W
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BU of 4d7w by Molmil
Crystal structure of sortase C1 (SrtC1) from Streptococcus agalactiae
分子名称: 1,2-ETHANEDIOL, SORTASE FAMILY PROTEIN
著者Malito, E, Lazzarin, M, Cozzi, R, Bottomley, M.J.
登録日2014-11-28
公開日2015-08-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Noncanonical Sortase-Mediated Assembly of Pilus Type 2B in Group B Streptococcus.
Faseb J., 29, 2015
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