7AA5
| Human TRPV4 structure in presence of 4a-PDD | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily V member 4,Green fluorescent protein | 著者 | Botte, M, Ulrich, A.K.G, Adaixo, R, Gnutt, D, Brockmann, A, Bucher, D, Chami, M, Bocquet, M, Ebbinghaus-Kintscher, U, Puetter, V, Becker, A, Egner, U, Stahlberg, H, Hennig, M, Holton, S.J. | 登録日 | 2020-09-03 | 公開日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation To Be Published
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7OMM
| Cryo-EM structure of N. gonorhoeae LptDE in complex with ProMacrobodies (MBPs have not been built de novo) | 分子名称: | LPS-assembly lipoprotein LptE, LPS-assembly protein LptD, ProMacrobody 21,Maltodextrin-binding protein, ... | 著者 | Botte, M, Ni, D, Schenck, S, Zimmermann, I, Chami, M, Bocquet, N, Egloff, P, Bucher, D, Trabuco, M, Cheng, R.K.Y, Brunner, J.D, Seeger, M.A, Stahlberg, H, Hennig, M. | 登録日 | 2021-05-24 | 公開日 | 2022-05-04 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation. Nat Commun, 13, 2022
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7OMT
| Crystal structure of ProMacrobody 21 with bound maltose | 分子名称: | HEXAETHYLENE GLYCOL, MAGNESIUM ION, ProMacrobody 21, ... | 著者 | Botte, M, Ni, D, Schenck, S, Zimmermann, I, Chami, M, Bocquet, N, Egloff, P, Bucher, D, Trabuco, M, Cheng, R.K.Y, Brunner, J.D, Seeger, M.A, Stahlberg, H, Hennig, M. | 登録日 | 2021-05-24 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation. Nat Commun, 13, 2022
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7PQT
| Apo human Kv3.1 cryo-EM structure | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 | 著者 | Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. | 登録日 | 2021-09-20 | 公開日 | 2022-08-17 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
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7PQU
| Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563) | 分子名称: | 1-(4-methylphenyl)sulfonyl-N-(1,3-oxazol-2-ylmethyl)pyrrole-3-carboxamide, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 | 著者 | Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. | 登録日 | 2021-09-20 | 公開日 | 2022-08-17 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
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2J80
| Structure of Citrate-bound Periplasmic Domain of Sensor Histidine Kinase CitA | 分子名称: | CITRATE ANION, GLYCEROL, SENSOR KINASE CITA, ... | 著者 | Sevvana, M, Vijayan, V, Zweckstetter, M, Reinelt, S, Madden, D.R, Sheldrick, G.M, Bott, M, Griesinger, C, Becker, S. | 登録日 | 2006-10-18 | 公開日 | 2007-10-23 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita. J.Mol.Biol., 377, 2008
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5MG3
| EM fitted model of bacterial holo-translocon | 分子名称: | Membrane protein insertase YidC, Protein translocase subunit SecD, Protein translocase subunit SecE, ... | 著者 | Schaffitzel, C, Botte, M. | 登録日 | 2016-11-20 | 公開日 | 2016-12-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion. Sci Rep, 6, 2016
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4QCJ
| Crystal Structure of OdhI from Corynebacterium glutamicum | 分子名称: | Oxoglutarate dehydrogenase inhibitor | 著者 | Labahn, J, Raasch, K, Eggeling, L, Bocola, M, Leitner, A, Bott, M. | 登録日 | 2014-05-12 | 公開日 | 2014-07-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model. J.Biotechnol., 191, 2014
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3PCQ
| Femtosecond X-ray protein Nanocrystallography | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Chapman, H.N, Fromme, P, Barty, A, White, T.A, Kirian, R.A, Aquila, A, Hunter, M.S, Schulz, J, Deponte, D.P, Weierstall, U, Doak, R.B, Maia, F.R.N.C, Martin, A.V, Schlichting, I, Lomb, L, Coppola, N, Shoeman, R.L, Epp, S.W, Hartmann, R, Rolles, D, Rudenko, A, Foucar, L, Kimmel, N, Weidenspointner, G, Holl, P, Liang, M, Barthelmess, M, Caleman, C, Boutet, S, Bogan, M.J, Krzywinski, J, Bostedt, C, Bajt, S, Gumprecht, L, Rudek, B, Erk, B, Schmidt, C, Homke, A, Reich, C, Pietschner, D, Struder, L, Hauser, G, Gorke, H, Ullrich, J, Herrmann, S, Schaller, G, Schopper, F, Soltau, H, Kuhnel, K.-U, Messerschmidt, M, Bozek, J.D, Hau-Riege, S.P, Frank, M, Hampton, C.Y, Sierra, R, Starodub, D, Williams, G.J, Hajdu, J, Timneanu, N, Seibert, M.M, Andreasson, J, Rocker, A, Jonsson, O, Svenda, M, Stern, S, Nass, K, Andritschke, R, Schroter, C.-D, Krasniqi, F, Bott, M, Schmidt, K.E, Wang, X, Grotjohann, I, Holton, J.M, Barends, T.R.M, Neutze, R, Marchesini, S, Fromme, R, Schorb, S, Rupp, D, Adolph, M, Gorkhover, T, Andersson, I, Hirsemann, H, Potdevin, G, Graafsma, H, Nilsson, B, Spence, J.C.H. | 登録日 | 2010-10-21 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (8.984 Å) | 主引用文献 | Femtosecond X-ray protein nanocrystallography. Nature, 470, 2011
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7Q21
| III2-IV2 respiratory supercomplex from Corynebacterium glutamicum | 分子名称: | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | 著者 | Kovalova, T, Moe, A, Krol, S, Yanofsky, D.J, Bott, M, Sjostrand, D, Rubinstein, J.L, Hogbom, M, Brzezinski, P. | 登録日 | 2021-10-22 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The respiratory supercomplex from C. glutamicum. Structure, 30, 2022
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4CYD
| GlxR bound to cAMP | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, PROBABLE EXPRESSION TAG, ... | 著者 | Townsend, P.D, Bott, M, Cann, M.J, Pohl, E. | 登録日 | 2014-04-10 | 公開日 | 2014-12-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors. Plos One, 9, 2014
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2V9A
| Structure of Citrate-free Periplasmic Domain of Sensor Histidine Kinase CitA | 分子名称: | SENSOR KINASE CITA | 著者 | Sevvana, M, Vijayan, V, Zweckstetter, M, Reinelt, S, Madden, D.R, Sheldrick, G.M, Bott, M, Griesinger, C, Becker, S. | 登録日 | 2007-08-23 | 公開日 | 2008-03-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita. J.Mol.Biol., 377, 2008
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4AF5
| Structure of the C. glutamicum AcnR Crystal Form I | 分子名称: | CITRIC ACID, HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR COMPND 2, MAGNESIUM ION | 著者 | Garcia-Nafria, J, Baumgart, M, Turkenburg, J.P, Wilkinson, A.J, Bott, M, Wilson, K.S. | 登録日 | 2012-01-17 | 公開日 | 2013-01-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket. J.Biol.Chem., 288, 2013
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4ACI
| Structure of the C. glutamicum AcnR Crystal Form II | 分子名称: | CITRIC ACID, GLYCEROL, HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR, ... | 著者 | Garcia-Nafria, J, Baumgart, M, Turkenburg, J.P, Wilkinson, A.J, Bott, M, Wilson, K.S. | 登録日 | 2011-12-15 | 公開日 | 2012-12-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket. J.Biol.Chem., 288, 2013
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3F52
| Crystal structure of the clp gene regulator ClgR from C. glutamicum | 分子名称: | GLYCEROL, clp gene regulator (ClgR) | 著者 | Russo, S, Schweitzer, J.E, Polen, T, Bott, M, Pohl, E. | 登録日 | 2008-11-03 | 公開日 | 2008-11-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes J.Biol.Chem., 284, 2009
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3F51
| Crystal Structure of the clp gene regulator ClgR from Corynebacterium glutamicum | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Clp gene regulator (ClgR) | 著者 | Russo, S, Schweitzer, J.E, Polen, T, Bott, M, Pohl, E. | 登録日 | 2008-11-03 | 公開日 | 2008-11-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes J.Biol.Chem., 284, 2009
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4AC6
| Corynebacterium glutamicum AcnR AU derivative structure | 分子名称: | GOLD ION, HTH-TYPE TRANSCRIPTIONAL REPRESSOR ACNR | 著者 | Garcia-Nafria, J, Baumgart, M, Turkenburg, J.P, Wilkinson, A.J, Bott, M, Wilson, K.S. | 登録日 | 2011-12-14 | 公開日 | 2012-12-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Crystal and Solution Studies Reveal that the Transcriptional Regulator Acnr of Corynebacterium Glutamicum is Regulated by Citrate:Mg2+ Binding to a Non-Canonical Pocket. J.Biol.Chem., 288, 2013
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1P0Z
| Sensor Kinase CitA binding domain | 分子名称: | CITRATE ANION, MO(VI)(=O)(OH)2 CLUSTER, SODIUM ION, ... | 著者 | Reinelt, S, Hofmann, E, Gerharz, T, Bott, M, Madden, D.R. | 登録日 | 2003-04-11 | 公開日 | 2003-08-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain. J.Biol.Chem., 278, 2003
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