4WB0
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4EHM
| RabGGTase in complex with covalently bound Psoromic acid | Descriptor: | 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-6-carboxylic acid, CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, ... | Authors: | Guo, Z, Deraeve, C, Bon, R.S, Alexandrov, K, Waldmann, H, Wu, Y.W, Goody, R.S, Blankenfeldt, W. | Deposit date: | 2012-04-02 | Release date: | 2012-05-30 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase J.Am.Chem.Soc., 134, 2012
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8B4A
| Nativ complex of PqsE and RhlR with autoinducer C4-HSL | Descriptor: | 2-aminobenzoylacetyl-CoA thioesterase, FE (III) ION, N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, ... | Authors: | Borgert, S.R, Blankenfeldt, W. | Deposit date: | 2022-09-20 | Release date: | 2022-12-14 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
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6TV2
| Heme d1 biosynthesis associated Protein NirF | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, Protein NirF, ... | Authors: | Kluenemann, T, Layer, G, Blankenfeldt, W. | Deposit date: | 2020-01-08 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.561 Å) | Cite: | Crystal structure of NirF: insights into its role in heme d 1 biosynthesis. Febs J., 288, 2021
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6TV9
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4ZFK
| Ergothioneine-biosynthetic Ntn hydrolase EgtC with glutamine | Descriptor: | 1,2-ETHANEDIOL, Amidohydrolase EgtC, GLUTAMINE | Authors: | Vit, A, Seebeck, F.P, Blankenfeldt, W. | Deposit date: | 2015-04-21 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC. Chembiochem, 16, 2015
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4ZFJ
| Ergothioneine-biosynthetic Ntn hydrolase EgtC, apo form | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Amidohydrolase EgtC | Authors: | Vit, A, Seebeck, F.P, Blankenfeldt, W. | Deposit date: | 2015-04-21 | Release date: | 2015-07-01 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC. Chembiochem, 16, 2015
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2Q0I
| Structure of Pseudomonas Quinolone Signal Response Protein PqsE | Descriptor: | BENZOIC ACID, FE (III) ION, Quinolone signal response protein | Authors: | Yu, S, Jensen, V, Feldmann, I, Haussler, S, Blankenfeldt, W. | Deposit date: | 2007-05-22 | Release date: | 2008-06-03 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein. Biochemistry, 48, 2009
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8BCI
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8BCJ
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5HWP
| MvaS with acetylated Cys115 in complex with coenzyme A | Descriptor: | COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | Authors: | Bock, T, Kasten, J, Blankenfeldt, W. | Deposit date: | 2016-01-29 | Release date: | 2016-05-11 | Last modified: | 2016-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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5HWO
| MvaS in complex with 3-hydroxy-3-methylglutaryl coenzyme A | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | Authors: | Bock, T, Kasten, J, Blankenfeldt, W. | Deposit date: | 2016-01-29 | Release date: | 2016-05-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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5HWQ
| MvaS in complex with acetoacetyl coenzyme A | Descriptor: | ACETOACETYL-COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | Authors: | Bock, T, Kasten, J, Blankenfeldt, W. | Deposit date: | 2016-01-29 | Release date: | 2016-05-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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5HWR
| MvaS in complex with coenzyme A | Descriptor: | COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | Authors: | Bock, T, Kasten, J, Blankenfeldt, W. | Deposit date: | 2016-01-29 | Release date: | 2016-05-11 | Last modified: | 2016-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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6TUK
| Crystal structure of Fdr9 | Descriptor: | (R,R)-2,3-BUTANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, Putative oxidoreductase, ... | Authors: | Rodriguez, A, Kluenemann, T, Blankenfeldt, W, Schallmey, A. | Deposit date: | 2020-01-07 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Expression, purification and crystal structure determination of a ferredoxin reductase from the actinobacterium Thermobifida fusca. Acta Crystallogr.,Sect.F, 76, 2020
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6TJL
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6TSI
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3B4O
| Crystal structure of phenazine biosynthesis protein PhzA/B from Burkholderia cepacia R18194, apo form | Descriptor: | ACETATE ION, Phenazine biosynthesis protein A/B | Authors: | Ahuja, E.G, Janning, P, Mentel, M, Graebsch, A, Breinbauer, R, Blankenfeldt, W. | Deposit date: | 2007-10-24 | Release date: | 2008-12-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis. J.Am.Chem.Soc., 130, 2008
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6ZTH
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6ZTI
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7P4U
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6RTE
| Dihydro-heme d1 dehydrogenase NirN in complex with DHE | Descriptor: | (R,R)-2,3-BUTANEDIOL, Cytochrome c, HEME C | Authors: | Kluenemann, T, Preuss, A, Layer, G, Blankenfeldt, W. | Deposit date: | 2019-05-23 | Release date: | 2019-06-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal Structure of Dihydro-Heme d1Dehydrogenase NirN from Pseudomonas aeruginosa Reveals Amino Acid Residues Essential for Catalysis. J.Mol.Biol., 431, 2019
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7QY3
| Crystal structure of the halohydrin dehalogenase HheG D114C mutant cross-linked with BMOE | Descriptor: | 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), Putative oxidoreductase, SULFATE ION | Authors: | Henke, S, Blankenfeldt, W, Schallmey, A. | Deposit date: | 2022-01-27 | Release date: | 2022-03-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Biocatalytically active and stable cross-linked enzyme crystals of halohydrin dehalogenase HheG by protein engineering Chemcatchem, 2022
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5JGL
| Crystal structure of GtmA in complex with S-Adenosylmethionine | Descriptor: | S-ADENOSYLMETHIONINE, SODIUM ION, UbiE/COQ5 family methyltransferase, ... | Authors: | Dolan, S.K, Bock, T, Hering, V, Jones, G.W, Blankenfeldt, W, Doyle, S. | Deposit date: | 2016-04-20 | Release date: | 2017-03-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural, mechanistic and functional insight into gliotoxinbis-thiomethylation inAspergillus fumigatus. Open Biol, 7, 2017
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7QA0
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