1JQZ
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![BU of 1jqz by Molmil](/molmil-images/mine/1jqz) | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag. | Descriptor: | FORMIC ACID, acidic fibroblast growth factor | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | Deposit date: | 2001-08-09 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil. Protein Sci., 10, 2001
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1JT3
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![BU of 1jt3 by Molmil](/molmil-images/mine/1jt3) | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V) | Descriptor: | SULFATE ION, acidic fibroblast growth factor | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | Deposit date: | 2001-08-20 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil. Protein Sci., 10, 2001
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2HZ9
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![BU of 2hz9 by Molmil](/molmil-images/mine/2hz9) | Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution. | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-08 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions J.Mol.Biol., 371, 2007
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2NTD
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![BU of 2ntd by Molmil](/molmil-images/mine/2ntd) | |
4YOL
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![BU of 4yol by Molmil](/molmil-images/mine/4yol) | Human fibroblast growth factor-1 C16S/A66C/C117A/P134A | Descriptor: | CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE | Authors: | Xia, X, Blaber, M. | Deposit date: | 2015-03-11 | Release date: | 2016-03-16 | Last modified: | 2019-02-13 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application. J.Pharm.Sci., 105, 2016
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9ILB
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![BU of 9ilb by Molmil](/molmil-images/mine/9ilb) | HUMAN INTERLEUKIN-1 BETA | Descriptor: | PROTEIN (HUMAN INTERLEUKIN-1 BETA) | Authors: | Yu, B, Blaber, M, Gronenborn, A.M, Clore, G.M, Caspar, D.L.D. | Deposit date: | 1998-10-22 | Release date: | 1999-01-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography. Proc.Natl.Acad.Sci.USA, 96, 1999
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1JT5
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![BU of 1jt5 by Molmil](/molmil-images/mine/1jt5) | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L) | Descriptor: | SULFATE ION, acidic fibroblast growth factor | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | Deposit date: | 2001-08-20 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil. Protein Sci., 10, 2001
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1JT4
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![BU of 1jt4 by Molmil](/molmil-images/mine/1jt4) | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L) | Descriptor: | FORMIC ACID, acidic fibroblast growth factor | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | Deposit date: | 2001-08-20 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil. Protein Sci., 10, 2001
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1JT7
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![BU of 1jt7 by Molmil](/molmil-images/mine/1jt7) | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L) | Descriptor: | FORMIC ACID, SULFATE ION, acidic fibroblast growth factor | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | Deposit date: | 2001-08-20 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil. Protein Sci., 10, 2001
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1SPJ
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![BU of 1spj by Molmil](/molmil-images/mine/1spj) | STRUCTURE OF MATURE HUMAN TISSUE KALLIKREIN (HUMAN KALLIKREIN 1 OR KLK1) AT 1.70 ANGSTROM RESOLUTION WITH VACANT ACTIVE SITE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ... | Authors: | Laxmikanthan, G, Blaber, S.I, Bernett, M.J, Blaber, M. | Deposit date: | 2004-03-16 | Release date: | 2005-01-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | 1.70 A X-ray structure of human apo kallikrein 1: Structural changes upon peptide inhibitor/substrate binding Proteins, 58, 2005
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1K5V
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![BU of 1k5v by Molmil](/molmil-images/mine/1k5v) | |
1L2E
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![BU of 1l2e by Molmil](/molmil-images/mine/1l2e) | Human Kallikrein 6 (hK6) Active Form with benzamidine inhibitor | Descriptor: | BENZAMIDINE, Kallikrein 6, MAGNESIUM ION | Authors: | Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Blaber, M. | Deposit date: | 2002-02-20 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J.Biol.Chem., 277, 2002
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1LO6
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![BU of 1lo6 by Molmil](/molmil-images/mine/1lo6) | Human Kallikrein 6 (hK6) active form with benzamidine inhibitor at 1.56 A resolution | Descriptor: | BENZAMIDINE, Kallikrein 6, MAGNESIUM ION | Authors: | Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Dhanarajan, P, Thompson, S.M, Blaber, M. | Deposit date: | 2002-05-06 | Release date: | 2002-05-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal structure and biochemical characterization of human kallikrein 6 reveals a
trypsin-like kallikrein is expressed in the central nervous system To be Published
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1K5U
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![BU of 1k5u by Molmil](/molmil-images/mine/1k5u) | |
2HWA
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![BU of 2hwa by Molmil](/molmil-images/mine/2hwa) | Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution. | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-01 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
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2HW9
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![BU of 2hw9 by Molmil](/molmil-images/mine/2hw9) | Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution. | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-01 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
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2HWM
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![BU of 2hwm by Molmil](/molmil-images/mine/2hwm) | Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | Authors: | Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M. | Deposit date: | 2006-08-01 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. J.Mol.Biol., 371, 2007
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1A80
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![BU of 1a80 by Molmil](/molmil-images/mine/1a80) | Native 2,5-DIKETO-D-GLUCONIC acid reductase a from CORYNBACTERIUM SP. complexed with nadph | Descriptor: | 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Khurana, S, Powers, D.B, Anderson, S, Blaber, M. | Deposit date: | 1998-03-31 | Release date: | 1999-03-30 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolution. Proc.Natl.Acad.Sci.USA, 95, 1998
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1HW6
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![BU of 1hw6 by Molmil](/molmil-images/mine/1hw6) | |
1JY0
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![BU of 1jy0 by Molmil](/molmil-images/mine/1jy0) | |
3O3Q
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![BU of 3o3q by Molmil](/molmil-images/mine/3o3q) | |
1P63
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![BU of 1p63 by Molmil](/molmil-images/mine/1p63) | Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I) | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION | Authors: | Brych, S.R, Kim, J, Logan, T.M, Blaber, M. | Deposit date: | 2003-04-28 | Release date: | 2004-05-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Accommodation of a highly symmetric core within a symmetric protein
superfold Protein Sci., 12, 2003
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1RG8
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![BU of 1rg8 by Molmil](/molmil-images/mine/1rg8) | |
1Q04
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![BU of 1q04 by Molmil](/molmil-images/mine/1q04) | Crystal structure of FGF-1, S50E/V51N | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1 | Authors: | Kim, J, Blaber, M. | Deposit date: | 2003-07-15 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor Protein Sci., 14, 2005
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1Q03
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![BU of 1q03 by Molmil](/molmil-images/mine/1q03) | Crystal structure of FGF-1, S50G/V51G mutant | Descriptor: | Heparin-binding growth factor 1 | Authors: | Kim, J, Blaber, M. | Deposit date: | 2003-07-15 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor Protein Sci., 14, 2005
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