Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 150 件
2I2C
DownloadVisualize
BU of 2i2c by Molmil
Crystal structure of LmNADK1
分子名称: (2S,3S,4R,5R,2'S,3'S,4'R,5'R)-2,2'-[DITHIOBIS(METHYLENE)]BIS[5-(6-AMINO-9H-PURIN-9-YL)TETRAHYDROFURAN-3,4-DIOL], Probable inorganic polyphosphate/ATP-NAD kinase 1, TETRAETHYLENE GLYCOL
著者Poncet-Montange, G, Labesse, G.
登録日2006-08-16
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2I29
DownloadVisualize
BU of 2i29 by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes
分子名称: CITRIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable inorganic polyphosphate/ATP-NAD kinase 1
著者Poncet-Montange, G, Assairi, L, Arold, S, Pochet, S, Labesse, G.
登録日2006-08-16
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
3GIN
DownloadVisualize
BU of 3gin by Molmil
Crystal structure of E454K-CBD1
分子名称: CALCIUM ION, Sodium/calcium exchanger 1
著者Chaptal, V, Mercado-Besserer, G, Abramson, J.
登録日2009-03-05
公開日2009-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and functional analysis of a Ca2+ sensor mutant of the na+/ca2+ exchanger
J.Biol.Chem., 284, 2009
7ZZ9
DownloadVisualize
BU of 7zz9 by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: 3-[[(2~{R},3~{S},4~{R},5~{R})-5-[8-[3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(2-azanylethyl)amino]prop-1-ynyl]-6-azanyl-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-3-oxidanylidene-propanoic acid, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZA
DownloadVisualize
BU of 7zza by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: 2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[6-azanyl-9-[(2~{R},3~{R},4~{S},5~{R})-5-[(3-azanylpropylcarbamoylamino)methyl]-3,4-bis(oxidanyl)oxolan-2-yl]purin-8-yl]prop-2-ynyl]amino]ethanoic acid, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZG
DownloadVisualize
BU of 7zzg by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: (1~{R},24~{R},25~{S},26~{R})-14-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-7-azanyl-25,26-bis(oxidanyl)-27-oxa-2,4,6,9,14,17,20,22-octazatetracyclo[22.2.1.0^{2,10}.0^{3,8}]heptacosa-3(8),4,6,9-tetraen-11-yne-16,21-dione, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZC
DownloadVisualize
BU of 7zzc by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: 2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[6-azanyl-9-[(2~{R},3~{R},4~{S},5~{R})-5-[(2-azanylethylsulfonylamino)methyl]-3,4-bis(oxidanyl)oxolan-2-yl]purin-8-yl]prop-2-ynyl]amino]ethanoic acid, CITRIC ACID, GLYCEROL, ...
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZF
DownloadVisualize
BU of 7zzf by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: (1~{R},23~{R},24~{S},25~{R})-14-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-7-azanyl-24,25-bis(oxidanyl)-26-oxa-2,4,6,9,14,17,21-heptazatetracyclo[21.2.1.0^{2,10}.0^{3,8}]hexacosa-3(8),4,6,9-tetraen-11-yne-18,20-dione, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZH
DownloadVisualize
BU of 7zzh by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: (1~{R},22~{R},23~{S},24~{R})-14-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-7-azanyl-23,24-bis(oxidanyl)-25-oxa-2,4,6,9,14,17,20-heptazatetracyclo[20.2.1.0^{2,10}.0^{3,8}]pentacosa-3(8),4,6,9-tetraen-11-yne-16,19-dione, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZJ
DownloadVisualize
BU of 7zzj by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: (1~{R},23~{R},24~{S},25~{R})-14-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-7-azanyl-24,25-bis(oxidanyl)-26-oxa-2,4,6,9,14,17,21-heptazatetracyclo[21.2.1.0^{2,10}.0^{3,8}]hexacosa-3(8),4,6,9-tetraen-11-yne-16,20-dione, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
8A9V
DownloadVisualize
BU of 8a9v by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: CITRIC ACID, NAD kinase 1, ~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-[8-[3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy]prop-1-ynyl]-6-azanyl-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-2-azanyl-ethanesulfonamide
著者Gelin, M, Labesse, G.
登録日2022-06-29
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.984 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZD
DownloadVisualize
BU of 7zzd by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: 2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[6-azanyl-9-[(2~{R},3~{R},4~{S},5~{R})-5-[(3-azanylpropanoylamino)methyl]-3,4-bis(oxidanyl)oxolan-2-yl]purin-8-yl]prop-2-ynyl]amino]ethanoic acid, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZ7
DownloadVisualize
BU of 7zz7 by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: 2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[6-azanyl-9-[(2~{R},3~{R},4~{S},5~{R})-5-[(2-azanylethanoylamino)methyl]-3,4-bis(oxidanyl)oxolan-2-yl]purin-8-yl]prop-2-ynyl]amino]ethanoic acid, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZB
DownloadVisualize
BU of 7zzb by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: 2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[6-azanyl-9-[(2~{R},3~{R},4~{S},5~{R})-5-[(2-azanylethylcarbamoylamino)methyl]-3,4-bis(oxidanyl)oxolan-2-yl]purin-8-yl]prop-2-ynyl]amino]ethanoic acid, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7ZZE
DownloadVisualize
BU of 7zze by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a linear di-adenosine derivative
分子名称: (1~{R},25~{R},26~{S},27~{R})-14-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-7-azanyl-26,27-bis(oxidanyl)-28-oxa-2,4,6,9,14,17,21,23-octazatetracyclo[23.2.1.0^{2,10}.0^{3,8}]octacosa-3(8),4,6,9-tetraen-11-yne-16,22-dione, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2022-05-25
公開日2023-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
7P3V
DownloadVisualize
BU of 7p3v by Molmil
B-Raf V600E structure bound to a new inhibitor
分子名称: Serine/threonine-protein kinase B-raf, ~{N}-[3-[5-(2-azanylpyrimidin-4-yl)-2-[(3~{S})-morpholin-3-yl]-1,3-thiazol-4-yl]-2-fluoranyl-phenyl]-2,5-bis(fluoranyl)benzenesulfonamide
著者Schneider, M, Gelin, M, Cohen-Gonsaud, M, Labesse, G.
登録日2021-07-08
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding.
J.Med.Chem., 65, 2022
8B47
DownloadVisualize
BU of 8b47 by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a cyclic di-adenosine derivative
分子名称: (1~{R},23~{R},24~{S},25~{R})-14-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-7-azanyl-24,25-bis(oxidanyl)-20,20-bis(oxidanylidene)-26-oxa-20$l^{6}-thia-2,4,6,9,14,17,21-heptazatetracyclo[21.2.1.0^{2,10}.0^{3,8}]hexacosa-3,5,7,9-tetraen-11-yn-16-one, NAD kinase 1, PENTAETHYLENE GLYCOL, ...
著者Gelin, M, Labesse, G.
登録日2022-09-20
公開日2023-01-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
Eur.J.Med.Chem., 246, 2023
4U77
DownloadVisualize
BU of 4u77 by Molmil
BTB domain from Drosophila CP190
分子名称: Centrosome-associated zinc finger protein CP190, DIMETHYL SULFOXIDE, GLYCEROL
著者Allemand, F, Cohen-Gonsaud, M, Labesse, G, Nollmann, M.
登録日2014-07-30
公開日2014-08-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome.
Plos Genet., 10, 2014
7BL7
DownloadVisualize
BU of 7bl7 by Molmil
Crystal structure of UMPK from M. tuberculosis in complex with UDP and UTP (P21212 form)
分子名称: URIDINE 5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE, Uridylate kinase
著者Walter, P, Labesse, G, Haouz, A, Mechaly, A.E, Munier-Lehmann, H.
登録日2021-01-18
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Febs J., 289, 2022
5EJF
DownloadVisualize
BU of 5ejf by Molmil
Crystal structure of NAD kinase P101A mutant from Listeria monocytogenes
分子名称: NAD kinase 1
著者Poncet-Montange, G, Assairi, L, Gelin, M, Pochet, S, Labesse, G.
登録日2015-11-01
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structure of NAD kinase 1 from Listeria monocytogenes: P101A mutant
to be published
5EJG
DownloadVisualize
BU of 5ejg by Molmil
Crystal structure of NAD kinase P252D mutant from Listeria monocytogenes
分子名称: NAD kinase 1
著者Poncet-Montange, G, Assairi, L, Gelin, M, Pochet, S, Labesse, G.
登録日2015-11-01
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.877 Å)
主引用文献Crystal structure of NAD kinase 1 from Listeria monocytogenes: P252D mutant
to be published
4KXL
DownloadVisualize
BU of 4kxl by Molmil
Crystal structure of DNPH1 (RCL) with 6-CYCLOPENTYL-AMP
分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, N-cyclopentyladenosine 5'-(dihydrogen phosphate), SULFATE ION
著者Padilla, A, Labesse, G, Kaminski, P.A.
登録日2013-05-27
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1.
Plos One, 8, 2013
4KXN
DownloadVisualize
BU of 4kxn by Molmil
Crystal structure of DNPH1 (RCL) with kinetine riboside monophosphate
分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, N-(furan-2-ylmethyl)adenosine 5'-(dihydrogen phosphate)
著者Padilla, A, Labesse, G, Kaminski, P.A.
登録日2013-05-27
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1.
Plos One, 8, 2013
5EJI
DownloadVisualize
BU of 5eji by Molmil
Crystal structure of NAD kinase W78F mutant from Listeria monocytogenes in complex with NADP/Mn++/PPi
分子名称: CITRIC ACID, MANGANESE (II) ION, NAD kinase 1, ...
著者Poncet-Montange, G, Assairi, L, Gelin, M, Pochet, S, Labesse, G.
登録日2015-11-01
公開日2016-11-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献Crystal structure of NAD kinase W78F mutant from Listeria monocytogenes in complex with NADP/Mn++/PPi
to be published
5EJH
DownloadVisualize
BU of 5ejh by Molmil
Crystal structure of NAD kinase V98S mutant from Listeria monocytogenes
分子名称: CITRIC ACID, NAD kinase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Poncet-Montange, G, Assairi, L, Gelin, M, Pochet, S, Labesse, G.
登録日2015-11-01
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of NAD kinase 1 from Listeria monocytogenes: V98S mutant
to be published

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon