6E53
 
 | | Structure of TERT in complex with a novel telomerase inhibitor | | 分子名称: | MAGNESIUM ION, RNA/DNA hairpin, Telomerase reverse transcriptase, ... | | 著者 | Hernandez-Sanchez, W, Huang, W, Plucinsky, B, Garcia-Vazquez, N, Berdis, A.J, Skordalakes, E, Taylor, D.J. | | 登録日 | 2018-07-19 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol., 17, 2019
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3RSR
 | | Crystal Structure of 5-NITP Inhibition of Yeast Ribonucleotide Reductase | | 分子名称: | 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO-1H-INDOLE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 | | 著者 | Wan, Q, Mohammed, F, Jha, S, Motea, E, Berdis, A, Dealwis, C.G. | | 登録日 | 2011-05-02 | | 公開日 | 2012-11-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase.
Mol.Cancer Ther., 11, 2012
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