2QAF
| Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-iodo-UMP | Descriptor: | Orotidine 5' monophosphate decarboxylase, SULFATE ION, URIDINE-5'-MONOPHOSPHATE | Authors: | Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F. | Deposit date: | 2007-06-15 | Release date: | 2008-04-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase J.Med.Chem., 51, 2008
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2E6Y
| Covalent complex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP | Descriptor: | GLYCEROL, Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | Authors: | Fujihashi, M, Bello, A.M, Kotra, L.P, Pai, E.F. | Deposit date: | 2007-01-05 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Potent, Covalent Inhibitor of Orotidine 5'-Monophosphate Decarboxylase with Antimalarial Activity. J.Med.Chem., 50, 2007
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2Q8Z
| Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase complexed with 6-amino-UMP | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 6-AMINOURIDINE 5'-MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F. | Deposit date: | 2007-06-12 | Release date: | 2008-01-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase. J.Med.Chem., 51, 2008
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1X1Z
| Orotidine 5'-monophosphate decarboxylase (odcase) complexed with BMP (produced from 6-cyanoump) | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | Authors: | Fujihashi, M, Bello, A.M, Poduch, E, Wei, L, Annedi, S.C, Pai, E.F, Kotra, L.P. | Deposit date: | 2005-04-15 | Release date: | 2005-12-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | An unprecedented twist to ODCase catalytic activity J.Am.Chem.Soc., 127, 2005
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3G3D
| Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 5-fluoro-6-azido-UMP | Descriptor: | 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | Authors: | Liu, Y, Tang, H.L, Bello, A, Poduch, E, Kotra, L, Pai, E. | Deposit date: | 2009-02-02 | Release date: | 2009-03-03 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents. J.Med.Chem., 52, 2009
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7TNG
| Kringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) | Descriptor: | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | Authors: | Guarino, S.R, Di Bello, A, Palamini, M, Forneris, F. | Deposit date: | 2022-01-21 | Release date: | 2022-05-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1) Acta Crystallogr.,Sect.F, 78, 2022
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3G3M
| Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 5-fluoro-6-iodo-UMP | Descriptor: | 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase | Authors: | Liu, Y, Tang, H.L, Bello, A.M, Poduch, E, Kotra, L.P, Pai, E.F. | Deposit date: | 2009-02-02 | Release date: | 2009-03-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents. J.Med.Chem., 52, 2009
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3DBP
| Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP | Descriptor: | 6-AMINOURIDINE 5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase, SULFATE ION | Authors: | Liu, Y, To, T, Bello, A.M, Kotra, L.P, Pai, E.F. | Deposit date: | 2008-06-02 | Release date: | 2009-06-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP To be Published
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3BAR
| Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-azido-UMP | Descriptor: | Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | Authors: | Liu, Y, Bello, A.M, Poduch, E, Lau, W, Kotra, L.P, Pai, E.F. | Deposit date: | 2007-11-08 | Release date: | 2008-01-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase. J.Med.Chem., 51, 2008
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3BGJ
| Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP | Descriptor: | GLYCEROL, URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase | Authors: | Liu, Y, Tang, H.L, Bello, A.M, Devalla, S, Kotra, L.P, Pai, E.F. | Deposit date: | 2007-11-26 | Release date: | 2008-11-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP To be Published
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3LIM
| Crystal structure of the pore forming toxin frac from sea anemone actinia fragacea | Descriptor: | Fragaceatoxin C, LAURYL DIMETHYLAMINE-N-OXIDE | Authors: | Mechaly, A.E, Bellomio, A, Morante, K, Gonzalez-Manas, J.M, Guerin, D.M.A. | Deposit date: | 2010-01-25 | Release date: | 2010-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the oligomerization and architecture of eukaryotic membrane pore-forming toxins. Structure, 19, 2011
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4LDT
| The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ... | Authors: | Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C. | Deposit date: | 2013-06-25 | Release date: | 2013-08-14 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nat.Struct.Mol.Biol., 20, 2013
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3ZWJ
| CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (Form 3) | Descriptor: | FRAGACEATOXIN C | Authors: | Mechaly, A.E, Bellomioa, A, Morantea, K, Gonzalez-Manas, J.M, Guerin, D.M.A. | Deposit date: | 2011-08-01 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Pores of the Toxin Frac Assemble Into 2D Hexagonal Clusters in Both Crystal Structures and Model Membranes. J.Struct.Biol., 180, 2012
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3ZWG
| Crystal structure of the pore-forming toxin FraC from Actinia fragacea (form 2) | Descriptor: | FRAGACEATOXIN C | Authors: | Mechaly, A.E, Bellomio, A, Morante, K, Gonzalez-Manas, J.M, Guerin, D.M.A. | Deposit date: | 2011-07-29 | Release date: | 2012-07-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Pores of the Toxin Frac Assemble Into 2D Hexagonal Clusters in Both Crystal Structures and Model Membranes. J.Struct.Biol., 180, 2012
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