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PDB: 388 件

1RYA
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BU of 1rya by Molmil
Crystal Structure of the E. coli GDP-mannose mannosyl hydrolase in complex with GDP and MG
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GDP-mannose mannosyl hydrolase, ...
著者Gabelli, S.B, Bianchet, M.A, Legler, P.M, Mildvan, A.S, Amzel, L.M.
登録日2003-12-20
公開日2004-06-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure and mechanism of GDP-mannose glycosyl hydrolase, a Nudix enzyme that cleaves at carbon instead of phosphorus.
Structure, 12, 2004
2RFS
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BU of 2rfs by Molmil
X-ray structure of SU11274 bound to c-Met
分子名称: Hepatocyte growth factor receptor, N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide
著者Bellon, S.F, Kaplan-Lefko, P, Yang, Y, Zhang, Y, Moriguchi, J, Dussault, I.
登録日2007-10-01
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations.
J.Biol.Chem., 283, 2008
2O5W
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BU of 2o5w by Molmil
Structure of the E. coli dihydroneopterin triphosphate pyrophosphohydrolase in complex with Sm+3 and pyrophosphate
分子名称: PYROPHOSPHATE, SAMARIUM (III) ION, SODIUM ION, ...
著者Gabelli, S.B, Bianchet, M.A, Amzel, L.M.
登録日2006-12-06
公開日2007-08-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis.
Structure, 15, 2007
2O1C
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Structure of the E. coli dihydroneopterin triphosphate pyrophosphohydrolase
分子名称: PYROPHOSPHATE, SULFATE ION, dATP pyrophosphohydrolase
著者Gabelli, S.B, Bianchet, M.A, Amzel, L.M.
登録日2006-11-28
公開日2007-08-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis.
Structure, 15, 2007
2RFN
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BU of 2rfn by Molmil
x-ray structure of c-Met with inhibitor.
分子名称: 2-benzyl-5-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-3-methylpyrimidin-4(3H)-one, Hepatocyte growth factor receptor
著者Bellon, S.F, Kaplan-Lefko, P, Yang, Y, Zhang, Y, Moriguchi, J, Dussault, I.
登録日2007-10-01
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations.
J.Biol.Chem., 283, 2008
1GA7
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BU of 1ga7 by Molmil
CRYSTAL STRUCTURE OF THE ADP-RIBOSE PYROPHOSPHATASE IN COMPLEX WITH GD+3
分子名称: GADOLINIUM ION, HYPOTHETICAL 23.7 KDA PROTEIN IN ICC-TOLC INTERGENIC REGION
著者Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M.
登録日2000-11-29
公開日2001-05-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family.
Nat.Struct.Biol., 8, 2001
1CM8
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BU of 1cm8 by Molmil
PHOSPHORYLATED MAP KINASE P38-GAMMA
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PHOSPHORYLATED MAP KINASE P38-GAMMA
著者Bellon, S, Fitzgibbon, M.J, Fox, T, Hsiao, H.M, Wilson, K.P.
登録日1999-05-17
公開日2000-05-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.
Structure Fold.Des., 7, 1999
2GT4
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BU of 2gt4 by Molmil
Crystal Structure of the Y103F mutant of the GDP-mannose mannosyl hydrolase in complex with GDP-mannose and MG+2
分子名称: GDP-mannose mannosyl hydrolase, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, ...
著者Gabelli, S.B, Bianchet, M.A, Azurmendi, H.F, Mildvan, A.S, Amzel, L.A.
登録日2006-04-27
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction.
Biochemistry, 45, 2006
2GT2
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Structure of the E. coli GDP-mannose mannosyl hydrolase
分子名称: GDP-mannose mannosyl hydrolase
著者Gabelli, S.B, Bianchet, M.A, Azurmendi, H.F, MIldvan, A.S, Amzel, L.M.
登録日2006-04-27
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction.
Biochemistry, 45, 2006
5T3Q
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BU of 5t3q by Molmil
Crystal structure of the c-Met kinase domain in complex with a pyrazolone inhibitor
分子名称: Hepatocyte growth factor receptor, N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
著者Bellon, S.F, Whittington, D.A, Long, A.M.
登録日2016-08-26
公開日2016-09-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of AMG337: Using structure guided scaffold hydridization to optimize physicochemical properties and target coverage of a MET kinase inhibitor
to be published
1KHZ
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BU of 1khz by Molmil
Structure of the ADPR-ase in complex with AMPCPR and Mg
分子名称: ADP-ribose pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, CHLORIDE ION, ...
著者Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M.
登録日2001-12-01
公開日2002-10-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase.
Biochemistry, 41, 2002
1RMD
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BU of 1rmd by Molmil
RAG1 DIMERIZATION DOMAIN
分子名称: RAG1, ZINC ION
著者Bellon, S.F, Rodgers, K.K, Schatz, D.G, Coleman, J.E, Steitz, T.A.
登録日1997-01-10
公開日1997-07-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster.
Nat.Struct.Biol., 4, 1997
1G9Q
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BU of 1g9q by Molmil
COMPLEX STRUCTURE OF THE ADPR-ASE AND ITS SUBSTRATE ADP-RIBOSE
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, HYPOTHETICAL 23.7 KDA PROTEIN IN ICC-TOLC INTERGENIC REGION
著者Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M.
登録日2000-11-27
公開日2001-05-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family.
Nat.Struct.Biol., 8, 2001
1G0S
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BU of 1g0s by Molmil
THE CRYSTAL STRUCTURE OF THE E.COLI ADP-RIBOSE PYROPHOSPHATASE
分子名称: HYPOTHETICAL 23.7 KDA PROTEIN IN ICC-TOLC INTERGENIC REGION
著者Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M.
登録日2000-10-08
公開日2001-05-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family.
Nat.Struct.Biol., 8, 2001
4V8S
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BU of 4v8s by Molmil
Archaeal RNAP-DNA binary complex at 4.32Ang
分子名称: 5'-D(*AP*TP*AP*GP*AP*GP*TP*AP*TP*AP*AP*GP*AP*TP *AP*G)-3', 5'-D(*TP*CP*TP*TP*AP*TP*AP*CP*TP*CP*TP*AP*TP*CP)-3', DNA-DIRECTED RNA POLYMERASE, ...
著者Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A.
登録日2012-07-12
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.323 Å)
主引用文献Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA.
Nucleic Acids Res., 40, 2012
2W2U
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BU of 2w2u by Molmil
STRUCTURAL INSIGHT INTO THE INTERACTION BETWEEN ARCHAEAL ESCRT-III AND AAA-ATPASE
分子名称: CONSERVED ARCHAEAL PROTEIN, HYPOTHETICAL P60 KATANIN
著者Obita, T, Samson, R.Y, Perisic, O, Freund, S.M, Bell, S.D, Williams, R.L.
登録日2008-11-04
公開日2009-07-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Role for the Escrt System in Cell Division in Archaea.
Science, 322, 2008
2WAQ
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BU of 2waq by Molmil
The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase
分子名称: DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ...
著者Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A.
登録日2009-02-11
公開日2009-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure.
Plos Biol., 7, 2009
4LTU
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BU of 4ltu by Molmil
Crystal Structure of Ferredoxin from Rhodopseudomonas palustris HaA2
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin
著者Zhou, W.H, Zhang, T, Yang, H, Bell, S.G, Wong, L.-L.
登録日2013-07-24
公開日2014-10-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal Structure of Ferredoxin from Rhodopseudomonas palustris HaA2
To be Published
6CVC
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BU of 6cvc by Molmil
Mycobacterium marinum cytochrome P450 CYP124A1 in the substrate-free form
分子名称: Cytochrome P450 124A1, Cyp124A1, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Child, S.A, Bruning, J.B, Bell, S.G.
登録日2018-03-27
公開日2019-03-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A comparison of the steroid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis
To Be Published
6DCD
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BU of 6dcd by Molmil
Mycobacterium marinum cytochrome P450 CYP150A6 in the substrate-free form
分子名称: Cytochrome P450 150A6 Cyp150A6, PROTOPORPHYRIN IX CONTAINING FE
著者Child, S.A, Bruning, J.B, Bell, S.G.
登録日2018-05-05
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The characterisation of two members of the cytochrome P450 CYP150 family: CYP150A5 and CYP150A6 from Mycobacterium marinum.
Biochim Biophys Acta Gen Subj, 1863, 2019
7SMZ
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BU of 7smz by Molmil
X-ray crystal structure of CYP142A3 from Mycobacterium Marinum in complex with 4-cholesten-3-one
分子名称: (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, ACETATE ION, Cytochrome P450 142A3, ...
著者Ghith, A, Bruning, J.B, Bell, S.G.
登録日2021-10-27
公開日2022-09-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum.
Acs Infect Dis., 8, 2022
3NV6
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BU of 3nv6 by Molmil
Crystal Structure of Camphor-Bound CYP101D2
分子名称: CAMPHOR, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ...
著者Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z.
登録日2010-07-08
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of CYP101D2 unveils a potential path for substrate entry into the active site
Biochem.J., 433, 2011
5N41
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BU of 5n41 by Molmil
Archaeal DNA polymerase holoenzyme - SSO6202 at 1.35 Ang resolution
分子名称: 1,2-ETHANEDIOL, PolB1 Binding Protein 2
著者Yan, J, Beattie, T.R, Rojas, A.L, Schermerhorn, K, Gristwood, T, Trinidad, J.C, Albers, S.V, Roversi, P, Gardner, A.F, Abrescia, N.G.A, Bell, S.D.
登録日2017-02-09
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.351 Å)
主引用文献Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.
Nat Commun, 8, 2017
5N35
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Gadolinium phased PBP2 (SSO6202) at 2.2 Ang
分子名称: GADOLINIUM ATOM, GLYCEROL, NITRATE ION, ...
著者Yan, J, Beattie, T.R, Rojas, A.L, Schermerhorn, K, Gristwood, T, Trinidad, J.C, Albers, S.V, Roversi, P, Gardner, A.F, Abrescia, N.G.A, Bell, S.D.
登録日2017-02-08
公開日2017-05-17
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.
Nat Commun, 8, 2017
6WZP
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BU of 6wzp by Molmil
The crystal structure of 4-vinylbenzoate-bound T252A mutant CYP199A4
分子名称: 4-ethenylbenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Coleman, T, Bruning, J.B, Bell, S.G.
登録日2020-05-14
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Understanding the Mechanistic Requirements for Efficient and Stereoselective Alkene Epoxidation by a Cytochrome P450 Enzyme
Acs Catalysis, 11, 2021

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