3O6Z
| Structure of the D152A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++ | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Amzel, L.M, Gabelli, S.B, Boto, A.N. | 登録日 | 2010-07-29 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition. Proteins, 79, 2011
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3O69
| Structure of the E100A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++ | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GDP-mannose pyrophosphatase nudK, ... | 著者 | Amzel, L.M, Gabelli, S.B, Boto, A.N. | 登録日 | 2010-07-28 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition. Proteins, 79, 2011
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3Q1P
| Crystal structure of CDP-Chase | 分子名称: | Phosphohydrolase (MutT/nudix family protein), SULFATE ION | 著者 | Duong-Ly, K.C, Gabelli, S.B, Amzel, L.M. | 登録日 | 2010-12-17 | 公開日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Nudix Hydrolase CDP-Chase, a CDP-Choline Pyrophosphatase, Is an Asymmetric Dimer with Two Distinct Enzymatic Activities. J.Bacteriol., 193, 2011
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3Q4I
| Crystal structure of CDP-Chase in complex with Gd3+ | 分子名称: | GADOLINIUM ION, Phosphohydrolase (MutT/nudix family protein) | 著者 | Duong-Ly, K.C, Gabelli, S.B, Amzel, L.M. | 登録日 | 2010-12-23 | 公開日 | 2011-07-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Nudix Hydrolase CDP-Chase, a CDP-Choline Pyrophosphatase, Is an Asymmetric Dimer with Two Distinct Enzymatic Activities. J.Bacteriol., 193, 2011
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4DEH
| Crystal structure of c-Met in complex with triazolopyridinone inhibitor 3 | 分子名称: | 5-phenyl-3-(quinolin-6-ylmethyl)-3,5,6,7-tetrahydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one, Hepatocyte growth factor receptor | 著者 | Whittington, D.A, Bellon, S.F, Long, A.M. | 登録日 | 2012-01-20 | 公開日 | 2012-05-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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1PV3
| NMR Solution Structure of the Avian FAT-domain of Focal Adhesion Kinase | 分子名称: | Focal adhesion kinase 1 | 著者 | Prutzman, K.C, Gao, G, King, M.L, Iyer, V.V, Mueller, G.A, Schaller, M.D, Campbell, S.L. | 登録日 | 2003-06-26 | 公開日 | 2004-05-25 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The Focal Adhesion Targeting Domain of Focal Adhesion Kinase Contains a Hinge Region that Modulates Tyrosine 926 Phosphorylation. STRUCTURE, 12, 2004
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3HIZ
| Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. | 登録日 | 2009-05-20 | 公開日 | 2009-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
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3HHM
| Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin | 分子名称: | (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | 著者 | Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. | 登録日 | 2009-05-15 | 公開日 | 2009-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
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3ICZ
| Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 1-(2,2-Bis-phosphono-ethyl)-3-butyl-pyridinium and isopentenyl pyrophosphate | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 3-[(1E)-but-1-en-1-yl]-1-(2,2-diphosphonoethyl)pyridinium, Farnesyl pyrophosphate synthase, ... | 著者 | Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. | 登録日 | 2009-07-19 | 公開日 | 2010-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins, 78, 2010
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1NQZ
| The structure of a CoA pyrophosphatase from D. Radiodurans complexed with a magnesium ion | 分子名称: | CoA pyrophosphatase (MutT/nudix family protein), MAGNESIUM ION | 著者 | Kang, L.W, Gabelli, S.B, Bianchet, M.A, Xu, W.L, Bessman, M.J, Amzel, L.M. | 登録日 | 2003-01-23 | 公開日 | 2003-05-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of a coenzyme A pyrophosphatase from Deinococcus radiodurans: a member of the Nudix family. J.Bacteriol., 185, 2003
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1NQY
| The structure of a CoA pyrophosphatase from D. Radiodurans | 分子名称: | CoA pyrophosphatase (MutT/nudix family protein) | 著者 | Kang, L.W, Gabelli, S.B, Bianchet, M.A, Xu, W.L, Bessman, M.J, Amzel, L.M. | 登録日 | 2003-01-23 | 公開日 | 2003-05-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structure of a coenzyme A pyrophosphatase from Deinococcus radiodurans: a member of the Nudix family. J.Bacteriol., 185, 2003
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2RD0
| Structure of a human p110alpha/p85alpha complex | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Huang, C, Gabelli, S.B, Amzel, L.M. | 登録日 | 2007-09-20 | 公開日 | 2007-12-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science, 318, 2007
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1QVX
| SOLUTION STRUCTURE OF THE FAT DOMAIN OF FOCAL ADHESION KINASE | 分子名称: | Focal adhesion kinase 1 | 著者 | Gao, G, Prutzman, K.C, King, M.L, DeRose, E.F, London, R.E, Schaller, M.D, Campbell, S.L. | 登録日 | 2003-08-29 | 公開日 | 2004-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Solution Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase in Complex with a Paxillin LD Peptide: EVIDENCE FOR A TWO-SITE BINDING MODEL. J.Biol.Chem., 279, 2004
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