6TRZ
 
 | | Crystal structure of horse L ferritin (HoLf) Fe(III)-loaded for 15 minutes | | 分子名称: | CADMIUM ION, CHLORIDE ION, FE (III) ION, ... | | 著者 | Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S. | | 登録日 | 2019-12-19 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
|
|
6TSA
 | | Crystal structure of human L ferritin (HuLf) Fe(III)-loaded for 30 minutes | | 分子名称: | CADMIUM ION, FE (III) ION, Ferritin light chain, ... | | 著者 | Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S. | | 登録日 | 2019-12-20 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
|
|
6TSF
 | | Crystal structure of human L ferritin (HuLf) Fe(III)-loaded for 60 minutes | | 分子名称: | CADMIUM ION, FE (III) ION, Ferritin light chain, ... | | 著者 | Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S. | | 登録日 | 2019-12-20 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
|
|
6BUU
 | | Crystal structure of AKT1 (aa 144-480) with a bisubstrate | | 分子名称: | GLY-ARG-PRO-ARG-THR-THR-ZXW-PHE-ALA-GLU, MANGANESE (II) ION, RAC-alpha serine/threonine-protein kinase, ... | | 著者 | Chu, N, Gabelli, S.B, Cole, P.A. | | 登録日 | 2017-12-11 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Cell, 174, 2018
|
|
5I89
 | | Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02857790 | | 分子名称: | (4R)-6-(3-cyclopropyl-1-methyl-1H-indazol-5-yl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, ACETATE ION, CALCIUM ION, ... | | 著者 | Setser, J.W, Poy, F, Bellon, S.F. | | 登録日 | 2016-02-18 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).
Acs Med.Chem.Lett., 7, 2016
|
|
5KTU
 | | Crystal structure of the bromodomain of human CREBBP bound to pyrazolopiperidine scaffold | | 分子名称: | 1-(3-phenylazanyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl)ethanone, CREB-binding protein, DIMETHYL SULFOXIDE | | 著者 | Jayaram, H, Poy, F, Setser, J.W, Bellon, S.F. | | 登録日 | 2016-07-12 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.
J. Med. Chem., 59, 2016
|
|
5I29
 | | TAF1(2) bound to a pyrrolopyridone compound | | 分子名称: | CALCIUM ION, N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide, Transcription initiation factor TFIID subunit 1 | | 著者 | Tang, Y, Poy, F, Bellon, S.F. | | 登録日 | 2016-02-08 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.
J.Med.Chem., 59, 2016
|
|
5I86
 | | Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02778174 | | 分子名称: | (4R)-N-benzyl-4-methyl-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-6-carboxamide, 1,2-ETHANEDIOL, CREB-binding protein, ... | | 著者 | Jayaram, H, Poy, F, Setser, J.W, Bellon, S.F. | | 登録日 | 2016-02-18 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).
Acs Med.Chem.Lett., 7, 2016
|
|
6ALA
 | | Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) in complex with citrate | | 分子名称: | CITRATE ANION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-08-07 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
7UZR
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | | 分子名称: | Cyclic GMP-AMP synthase, MANGANESE (II) ION, Palindromic DNA18, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-09 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS
Nat Commun, 15, 2024
|
|
7V0C
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | | 分子名称: | Cyclic GMP-AMP synthase, MANGANESE (II) ION, Palindromic DNA18, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-10 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG
To Be Published
|
|
7V0R
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -ppcpG(2 ,5 )pA | | 分子名称: | Cyclic GMP-AMP synthase, MAGNESIUM ION, Palindromic DNA18, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-10 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -ppcpG(2 ,5 )pA
To Be Published
|
|
7UTT
 | |
6WBH
 | | Crystal structure of mRECK(CC4) in fusion with engineered MBP at medium resolution | | 分子名称: | CHLORIDE ION, Maltodextrin-binding protein,Reversion-inducing cysteine-rich protein with Kazal motifs fusion, ZINC ION, ... | | 著者 | Chang, T.H, Hsieh, F.L, Gabelli, S.B, Nathans, J. | | 登録日 | 2020-03-26 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.455 Å) | | 主引用文献 | Structure of the RECK CC domain, an evolutionary anomaly.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
5DBM
 | | Crystal structure of the CBP bromodomain in complex with CPI703 | | 分子名称: | (4R)-6-(1-tert-butyl-1H-pyrazol-4-yl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, CREB-binding protein | | 著者 | Setser, J.W, Poy, F, Bellon, S.F. | | 登録日 | 2015-08-21 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition.
J.Biol.Chem., 291, 2016
|
|
6TS0
 | | Crystal structure of human L ferritin (HuLf) triple variant E60A-E61A-E64A Fe(III)-loaded for 30 minutes | | 分子名称: | CADMIUM ION, FE (III) ION, Ferritin light chain, ... | | 著者 | Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S. | | 登録日 | 2019-12-19 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
|
|
5V84
 | | CECR2 in complex with Cpd6 (6-allyl-N,2-dimethyl-7-oxo-N-(1-(1-phenylethyl)piperidin-4-yl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-4-carboxamide) | | 分子名称: | Cat eye syndrome critical region protein 2, N,2-dimethyl-7-oxo-N-{1-[(1S)-1-phenylethyl]piperidin-4-yl}-6-(prop-2-en-1-yl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-4- carboxamide, SULFATE ION | | 著者 | Murray, J.M, Kiefer, J.R, Jayaran, H, Bellon, S, Boy, F. | | 登録日 | 2017-03-21 | | 公開日 | 2017-06-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).
ACS Med Chem Lett, 8, 2017
|
|
4HFQ
 | | Crystal structure of UDP-X diphosphatase | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Duong-Ly, K.C, Amzel, L.M, Gabelli, S.B. | | 登録日 | 2012-10-05 | | 公開日 | 2013-08-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | A UDP-X diphosphatase from Streptococcus pneumoniae hydrolyzes precursors of peptidoglycan biosynthesis.
Plos One, 8, 2013
|
|
3NPE
 | | Structure of VP14 in complex with oxygen | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 9-cis-epoxycarotenoid dioxygenase 1, chloroplastic, ... | | 著者 | Messing, S.A, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2010-06-28 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid.
Plant Cell, 22, 2010
|
|
6TS1
 | | Crystal structure of human L ferritin (HuLf) triple variant E60A-E61A-E64A Fe(III)-loaded for 60 minutes | | 分子名称: | CADMIUM ION, FE (III) ION, Ferritin light chain, ... | | 著者 | Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S. | | 登録日 | 2019-12-19 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
|
|
6TR9
 | | Crystal structure of human L ferritin (HuLf) triple variant E60A-E61A-E64A | | 分子名称: | CADMIUM ION, Ferritin light chain | | 著者 | Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S. | | 登録日 | 2019-12-18 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
|
|
6TSJ
 | | Crystal structure of human L ferritin (HuLf) Fe(III)-loaded for 15 minutes | | 分子名称: | CADMIUM ION, FE (III) ION, Ferritin light chain, ... | | 著者 | Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S. | | 登録日 | 2019-12-20 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
|
|
7UYQ
 | | Structure of GTP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination | | 分子名称: | Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-07 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS
Nat Commun, 15, 2024
|
|
7UYZ
 | | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | | 分子名称: | Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Wu, S, Gabelli, S.B, Sohn, J. | | 登録日 | 2022-05-07 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS
Nat Commun, 15, 2024
|
|
6ALV
 | | Crystal structure of H107A-peptidylglycine alpha-hydroxylating monooxygenase (PHM) mutant (no CuH bound) | | 分子名称: | AZIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-08-08 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
