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PDB: 18 件

4AOF
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Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma
分子名称: N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM
著者Bergamini, G, Bell, K, Shimamura, S, Werner, T, Cansfield, A, Muller, K, Perrin, J, Rau, C, Ellard, K, Hopf, C, Doce, C, Leggate, D, Mangano, R, Mathieson, T, OMahony, A, Plavec, I, Rharbaoui, F, Reinhard, F, Savitski, M.M, Ramsden, N, Hirsch, E, Drewes, G, Rausch, O, Bantscheff, M, Neubauer, G.
登録日2012-03-26
公開日2012-05-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A Selective Inhibitor Reveals Pi3Kgamma Dependence of T(H)17 Cell Differentiation.
Nat.Chem.Biol., 8, 2012
2O7K
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S. aureus thioredoxin
分子名称: Thioredoxin
著者Roos, G, Garcia-Pino, A, Van Belle, K, Brosens, E, Wahni, K, Vandenbussche, G, Wyns, L, Loris, R, Messens, J.
登録日2006-12-11
公開日2007-07-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin
J.Mol.Biol., 368, 2007
1RXI
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pI258 arsenate reductase (ArsC) triple mutant C10S/C15A/C82S
分子名称: Arsenate reductase, CHLORIDE ION, PERCHLORATE ION, ...
著者Messens, J, Van Molle, I, Vanhaesebrouck, P, Limbourg, M, Van Belle, K, Wahni, K, Martins, J.C, Loris, R, Wyns, L.
登録日2003-12-18
公開日2004-06-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.
Acta Crystallogr.,Sect.D, 60, 2004
1RXE
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ArsC complexed with MNB
分子名称: 5-MERCAPTO-2-NITRO-BENZOIC ACID, Arsenate reductase, PERCHLORATE ION, ...
著者Messens, J, Van Molle, I, Vanhaesebrouck, P, Limbourg, M, Van Belle, K, Wahni, K, Martins, J.C, Loris, R, Wyns, L.
登録日2003-12-18
公開日2004-06-01
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.
Acta Crystallogr.,Sect.D, 60, 2004
2CD7
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Staphylococcus aureus pI258 arsenate reductase (ArsC) H62Q mutant
分子名称: PROTEIN ARSC, SODIUM ION
著者Buts, L, Roos, G, Van Belle, K, Brosens, E, Loris, R, Wyns, L, Messens, J.
登録日2006-01-23
公開日2006-06-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Interplay between Ion Binding and Catalysis in the Thioredoxin-Coupled Arsenate Reductase Family.
J.Mol.Biol., 360, 2006
1LK0
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Disulfide intermediate of C89L Arsenate reductase from pI258
分子名称: CHLORIDE ION, POTASSIUM ION, arsenate reductase
著者Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I.
登録日2002-04-23
公開日2002-08-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
Proc.Natl.Acad.Sci.USA, 99, 2002
1LJL
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Wild Type pI258 S. aureus arsenate reductase
分子名称: POTASSIUM ION, arsenate reductase
著者Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I.
登録日2002-04-21
公開日2002-08-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
Proc.Natl.Acad.Sci.USA, 99, 2002
1T3S
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Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core
分子名称: Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, MERCURY (II) ION
著者Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A.
登録日2004-04-27
公開日2004-05-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain.
Neuron, 42, 2004
1T3L
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Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core in Complex with Alpha1 Interaction Domain
分子名称: Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, Voltage-dependent L-type calcium channel alpha-1S subunit
著者Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A.
登録日2004-04-27
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain
NEURON, 42, 2004
5IK7
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Laminin A2LG45 I-form, Apo.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK5
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Laminin A2LG45 C-form, G6/7 bound.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, CALCIUM ION, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK8
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Laminin A2LG45 I-form, G6/7 bound.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
3VRE
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BU of 3vre by Molmil
The crystal structure of hemoglobin from woolly mammoth in the deoxy form
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE
著者Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H.
登録日2012-04-09
公開日2012-11-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
5IK4
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Laminin A2LG45 C-form, Apo.
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Briggs, D.C, Hohenester, E, Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
7UI6
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CryoEM structure of LARGE1 from C1 reconstruction
分子名称: MANGANESE (II) ION, Xylosyl- and glucuronyltransferase LARGE1
著者Joseph, S, Schnicker, N.J, Campbell, K.P.
登録日2022-03-28
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献CryoEM structure of LARGE1 from C1 reconstruction
To Be Published
7UI7
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CryoEM structure of LARGE1 from C2 reconstruction
分子名称: MANGANESE (II) ION, Xylosyl- and glucuronyltransferase LARGE1
著者Schnicker, N.J, Joseph, S, Campbell, K.P.
登録日2022-03-28
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献CryoEM structure of LARGE1 from C2 reconstruction
To Be Published
3VRF
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The crystal structure of hemoglobin from woolly mammoth in the carbonmonoxy forms
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, ...
著者Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H.
登録日2012-04-09
公開日2012-11-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
3VRG
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The crystal structure of hemoglobin from woolly mammoth in the met form
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H.
登録日2012-04-09
公開日2012-11-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012

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件を2024-07-24に公開中

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