6Z3O
 
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6Z3N
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1VQB
 | | GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN) | | Descriptor: | GENE V PROTEIN | | Authors: | Skinner, M.M, Zhang, H, Leschnitzer, D.H, Guan, Y, Bellamy, H, Sweet, R.M, Gray, C.W, Konings, R.N.H, Wang, A.H.-J, Terwilliger, T.C. | | Deposit date: | 1996-08-14 | | Release date: | 1997-02-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein.
Proc.Natl.Acad.Sci.USA, 91, 1994
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5LS8
 | | Light-activated ruthenium complex bound to a DNA quadruplex | | Descriptor: | DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*A)-3'), POTASSIUM ION, delta-[Ru(tap2-dppz-CN)]2+, ... | | Authors: | McQuaid, K.T, Abell, H, Hall, J.P, Cardin, C.J. | | Deposit date: | 2016-08-22 | | Release date: | 2018-01-17 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structural Studies Reveal Enantiospecific Recognition of a DNA G-Quadruplex by a Ruthenium Polypyridyl Complex.
Angew.Chem.Int.Ed.Engl., 58, 2019
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5ACC
 | | A Novel Oral Selective Estrogen Receptor Down-regulator, AZD9496, drives Tumour Growth Inhibition in Estrogen Receptor positive and ESR1 Mutant Models | | Descriptor: | (E)-3-(3,5-DIFLUORO-4-((1R,3R)-2-(2-FLUORO-2- METHYLPROPYL)-3-METHYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOL-1-YL)PHENYL)ACRYLIC ACID, ESTROGEN RECEPTOR | | Authors: | Norman, R.A, Weir, H.M, Bradbury, R.H, Lawson, M, Rabow, A.A, Buttar, D, Callis, R.J, Curwen, J.O, de Almeida, C, Ballard, P, Hulse, M, Donald, C.S, Feron, L.J.L, Gingell, H, Karoutchi, G, MacFaul, P, Moss, T, Pearson, S.E, Tonge, M, Davies, G, Walker, G.E, Wilson, Z, Rowlinson, R, Powell, S, Hemsley, P, Linney, E, Campbell, H, Ghazoui, Z, Sadler, C, Richmond, G, Pazolli, E, Mazzola, A.M, DCruz, C, De Savi, C. | | Deposit date: | 2015-08-15 | | Release date: | 2015-12-16 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2, 3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.
J.Med.Chem., 58, 2015
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3KVT
 | | TETRAMERIZATION DOMAIN FROM AKV3.1 (SHAW-SUBFAMILY) VOLTAGE-GATED POTASSIUM CHANNEL | | Descriptor: | POTASSIUM CHANNEL PROTEIN SHAW, ZINC ION | | Authors: | Bixby, K.A, Nanao, M.H, Shen, N.V, Kreusch, A, Bellamy, H, Pfaffinger, P.J, Choe, S. | | Deposit date: | 1998-09-25 | | Release date: | 1999-01-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels.
Nat.Struct.Biol., 6, 1999
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4H9K
 | | Crystal structure of cleavage site mutant of Npro of classical swine fever virus. | | Descriptor: | Hog cholera virus, SULFATE ION, ZINC ION | | Authors: | Gottipati, K, Ruggli, N, Gerber, M, Tratschin, J.-D, Benning, M, Bellamy, H, Choi, K.H. | | Deposit date: | 2012-09-24 | | Release date: | 2013-10-30 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.599 Å) | | Cite: | The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction.
Plos Pathog., 9, 2013
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4H9J
 | | Crystal structure of N-terminal protease (Npro) of classical swine fever virus. | | Descriptor: | Hog cholera virus | | Authors: | Gottipati, K, Ruggli, N, Gerber, M, Tratschin, J.-D, Benning, M, Bellamy, H, Choi, K.H. | | Deposit date: | 2012-09-24 | | Release date: | 2013-10-30 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction.
Plos Pathog., 9, 2013
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1DVP
 | | CRYSTAL STRUCTURE OF THE VHS AND FYVE TANDEM DOMAINS OF HRS, A PROTEIN INVOLVED IN MEMBRANE TRAFFICKING AND SIGNAL TRANSDUCTION | | Descriptor: | CITRIC ACID, HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE, ZINC ION | | Authors: | Mao, Y, Nickitenko, A, Duan, X, Lloyd, T.E, Wu, M.N, Bellen, H, Quiocho, F.A. | | Deposit date: | 2000-01-21 | | Release date: | 2000-03-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction.
Cell(Cambridge,Mass.), 100, 2000
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2CUA
 | | THE CUA DOMAIN OF CYTOCHROME BA3 FROM THERMUS THERMOPHILUS | | Descriptor: | DINUCLEAR COPPER ION, PROTEIN (CUA), ZINC ION | | Authors: | Williams, P.A, Blackburn, N.J, Sanders, D, Bellamy, H, Stura, E.A, Fee, J.A, Mcree, D.E. | | Deposit date: | 1999-02-18 | | Release date: | 1999-05-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution.
Nat.Struct.Biol., 6, 1999
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3FAY
 | | Crystal structure of the GAP-related domain of IQGAP1 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ras GTPase-activating-like protein IQGAP1 | | Authors: | Kurella, V.B, Richard, J.M, Parke, C.L, Bellamy, H, Worthylake, D.K. | | Deposit date: | 2008-11-18 | | Release date: | 2009-03-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the GTPase-activating protein-related domain from IQGAP1.
J.Biol.Chem., 284, 2009
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2B3R
 | | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2 | | Descriptor: | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide, SULFATE ION | | Authors: | Liu, L, Song, X, He, D, Komma, C, Kita, A, Verbasius, J.V, Bellamy, H, Miki, K, Czech, M.P, Zhou, G.W. | | Deposit date: | 2005-09-20 | | Release date: | 2005-12-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2alpha.
J.Biol.Chem., 281, 2006
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