2FMN
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![BU of 2fmn by Molmil](/molmil-images/mine/2fmn) | Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase complex with LY309887 | Descriptor: | 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, N-[(5-{2-[(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-6-YL]ETHYL}-2-THIENYL)CARBONYL]-L-GLUTAMIC ACID | Authors: | Pejchal, R, Campbell, E, Guenther, B.D, Lennon, B.W, Matthews, R.G, Ludwig, M.L. | Deposit date: | 2006-01-09 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation Biochemistry, 45, 2006
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2FMO
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![BU of 2fmo by Molmil](/molmil-images/mine/2fmo) | Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Pejchal, R, Campbell, E, Guenther, B.D, Lennon, B.W, Matthews, R.G, Ludwig, M.L. | Deposit date: | 2006-01-09 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation Biochemistry, 45, 2006
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1KPL
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![BU of 1kpl by Molmil](/molmil-images/mine/1kpl) | Crystal Structure of the ClC Chloride Channel from S. typhimurium | Descriptor: | CHLORIDE ION, N-OCTANE, PENTADECANE, ... | Authors: | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | Deposit date: | 2001-12-31 | Release date: | 2002-01-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity. Nature, 415, 2002
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1OTS
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![BU of 1ots by Molmil](/molmil-images/mine/1ots) | Structure of the Escherichia coli ClC Chloride channel and Fab Complex | Descriptor: | CHLORIDE ION, Fab fragment (heavy chain), Fab fragment (light chain), ... | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | Deposit date: | 2003-03-22 | Release date: | 2003-04-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
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3NRX
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![BU of 3nrx by Molmil](/molmil-images/mine/3nrx) | Insights into anti-parallel microtubule crosslinking by PRC1, a conserved non-motor microtubule binding protein | Descriptor: | Protein regulator of cytokinesis 1 | Authors: | Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A. | Deposit date: | 2010-06-30 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein. Cell(Cambridge,Mass.), 142, 2010
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4JTD
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![BU of 4jtd by Molmil](/molmil-images/mine/4jtd) | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | Authors: | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | Deposit date: | 2013-03-23 | Release date: | 2013-06-12 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
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4JTC
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![BU of 4jtc by Molmil](/molmil-images/mine/4jtc) | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | Deposit date: | 2013-03-23 | Release date: | 2013-06-12 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
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3NRY
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![BU of 3nry by Molmil](/molmil-images/mine/3nry) | Insights into anti-parallel microtubule crosslinking by PRC1, a conserved microtubule binding protein | Descriptor: | Protein regulator of cytokinesis 1 | Authors: | Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A. | Deposit date: | 2010-07-01 | Release date: | 2010-08-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein. Cell(Cambridge,Mass.), 142, 2010
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1L9Z
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![BU of 1l9z by Molmil](/molmil-images/mine/1l9z) | Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution | Descriptor: | MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... | Authors: | Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A. | Deposit date: | 2002-03-27 | Release date: | 2002-05-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (6.5 Å) | Cite: | Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science, 296, 2002
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4JTA
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![BU of 4jta by Molmil](/molmil-images/mine/4jta) | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | Authors: | MacKinnon, R, Banerjee, A, Lee, A, Campbell, E. | Deposit date: | 2013-03-23 | Release date: | 2013-06-12 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
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4PCN
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![BU of 4pcn by Molmil](/molmil-images/mine/4pcn) | Phosphotriesterase variant R22 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase variant PTE-R22, ZINC ION | Authors: | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | Deposit date: | 2014-04-16 | Release date: | 2015-05-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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5AF0
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![BU of 5af0 by Molmil](/molmil-images/mine/5af0) | MAEL domain from Bombyx mori Maelstrom | Descriptor: | MAELSTROM, ZINC ION | Authors: | Chen, K, Campbell, E, Pandey, R.R, Yang, Z, McCarthy, A.A, Pillai, R.S. | Deposit date: | 2015-01-13 | Release date: | 2015-04-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Metazoan Maelstrom is an RNA-Binding Protein that Has Evolved from an Ancient Nuclease Active in Protists. RNA, 21, 2015
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5UI5
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![BU of 5ui5 by Molmil](/molmil-images/mine/5ui5) | |
2P7V
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![BU of 2p7v by Molmil](/molmil-images/mine/2p7v) | Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4 | Descriptor: | MAGNESIUM ION, RNA polymerase sigma factor rpoD, Regulator of sigma D | Authors: | Patikoglou, G.A, Westblade, L.F, Campbell, E.A, Lamour, V, Lane, W.J, Darst, S.A. | Deposit date: | 2007-03-20 | Release date: | 2007-08-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4. J.Mol.Biol., 372, 2007
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7JKA
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![BU of 7jka by Molmil](/molmil-images/mine/7jka) | |
7JIZ
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![BU of 7jiz by Molmil](/molmil-images/mine/7jiz) | |
2A79
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![BU of 2a79 by Molmil](/molmil-images/mine/2a79) | Mammalian Shaker Kv1.2 potassium channel- beta subunit complex | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ... | Authors: | Long, S.B, Campbell, E.B, MacKinnon, R. | Deposit date: | 2005-07-05 | Release date: | 2005-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science, 309, 2005
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1HQM
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![BU of 1hqm by Molmil](/molmil-images/mine/1hqm) | CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K. | Deposit date: | 2000-12-18 | Release date: | 2001-02-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. Proc.Natl.Acad.Sci.USA, 98, 2001
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2MKJ
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![BU of 2mkj by Molmil](/molmil-images/mine/2mkj) | Solution structure of tandem RRM domains of cytoplasmic polyadenylation element binding protein 4 (CPEB4) in free state | Descriptor: | Cytoplasmic polyadenylation element-binding protein 4 | Authors: | Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T. | Deposit date: | 2014-02-07 | Release date: | 2014-07-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins Genes Dev., 28, 2014
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2MKK
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![BU of 2mkk by Molmil](/molmil-images/mine/2mkk) | Structural model of tandem RRM domains of cytoplasmic polyadenylation element binding protein 1 (CPEB1) in complex with RNA | Descriptor: | Cytoplasmic polyadenylation element-binding protein 1, RNA (5'-R(*UP*UP*UP*UP*A)-3') | Authors: | Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T. | Deposit date: | 2014-02-07 | Release date: | 2014-07-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins Genes Dev., 28, 2014
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2MKI
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![BU of 2mki by Molmil](/molmil-images/mine/2mki) | Solution structure of tandem RRM domains of cytoplasmic polyadenylation element binding protein 4 (CPEB4) in complex with RNA | Descriptor: | Cytoplasmic polyadenylation element-binding protein 4, RNA (5'-R(*CP*UP*UP*UP*A)-3') | Authors: | Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T. | Deposit date: | 2014-02-07 | Release date: | 2014-07-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins Genes Dev., 28, 2014
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2MKH
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![BU of 2mkh by Molmil](/molmil-images/mine/2mkh) | Solution structure of tandem RRM domains of cytoplasmic polyadenylation element binding protein 1 (CPEB1) in free state | Descriptor: | Cytoplasmic polyadenylation element-binding protein 1 | Authors: | Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T. | Deposit date: | 2014-02-07 | Release date: | 2014-07-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins Genes Dev., 28, 2014
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2MKE
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![BU of 2mke by Molmil](/molmil-images/mine/2mke) | Solution structure of CPEB1 ZZ domain in the free state | Descriptor: | Cytoplasmic polyadenylation element-binding protein 1, ZINC ION | Authors: | Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T. | Deposit date: | 2014-02-06 | Release date: | 2014-07-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins Genes Dev., 28, 2014
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4L5G
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![BU of 4l5g by Molmil](/molmil-images/mine/4l5g) | Crystal structure of Thermus thermophilus CarD | Descriptor: | CarD | Authors: | Srivastava, D.B, Westblade, L.F, Campbell, E.A, Darst, S.A. | Deposit date: | 2013-06-11 | Release date: | 2013-07-31 | Last modified: | 2013-08-21 | Method: | X-RAY DIFFRACTION (2.3902 Å) | Cite: | Structure and function of CarD, an essential mycobacterial transcription factor. Proc.Natl.Acad.Sci.USA, 110, 2013
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6PSS
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![BU of 6pss by Molmil](/molmil-images/mine/6pss) | Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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