1YAK
 
 | | Complex of Bacillus subtilis TenA with 4-amino-2-methyl-5-hydroxymethylpyrimidine | | 分子名称: | 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, Transcriptional activator tenA | | 著者 | Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E. | | 登録日 | 2004-12-17 | | 公開日 | 2005-02-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
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1YFX
 | | Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and NO | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ... | | 著者 | Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E. | | 登録日 | 2005-01-04 | | 公開日 | 2005-05-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
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1XOB
 | | THIOREDOXIN (REDUCED DITHIO FORM), NMR, 20 STRUCTURES | | 分子名称: | THIOREDOXIN | | 著者 | Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J. | | 登録日 | 1995-11-28 | | 公開日 | 1996-06-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
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1YAD
 | | Structure of TenI from Bacillus subtilis | | 分子名称: | Regulatory protein tenI, SULFATE ION, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM | | 著者 | Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E. | | 登録日 | 2004-12-17 | | 公開日 | 2005-02-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
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1YFY
 | | Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 3-hydroxyanthranilic acid | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate-3,4-dioxygenase, ... | | 著者 | Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E. | | 登録日 | 2005-01-04 | | 公開日 | 2005-05-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
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1YAF
 | | Structure of TenA from Bacillus subtilis | | 分子名称: | Transcriptional activator tenA | | 著者 | Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E. | | 登録日 | 2004-12-17 | | 公開日 | 2005-02-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
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1EKK
 | | CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN THE R3 FORM WITH HYDROXYETHYLTHIAZOLE | | 分子名称: | 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, HYDROXYETHYLTHIAZOLE KINASE, SULFUR DIOXIDE | | 著者 | Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E. | | 登録日 | 2000-03-09 | | 公開日 | 2000-08-09 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
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1EKQ
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3DWM
 | | Crystal structure of Mycobacterium tuberculosis CysO, an antigen | | 分子名称: | 9.5 kDa culture filtrate antigen cfp10A | | 著者 | Jurgenson, C.T, Burns, K.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-07-22 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis.
Biochemistry, 47, 2008
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3EPM
 | | Crystal structure of Caulobacter crescentus ThiC | | 分子名称: | 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ... | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.793 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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4KYS
 | | Clostridium botulinum thiaminase I in complex with thiamin | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, CITRIC ACID, MAGNESIUM ION, ... | | 著者 | Sikowitz, M.D, Shome, B, Zhang, Y, Begley, T.P, Ealick, S.E. | | 登録日 | 2013-05-29 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structure of a Clostridium botulinum C143S Thiaminase I/Thiamin Complex Reveals Active Site Architecture.
Biochemistry, 52, 2013
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4JEL
 | | Structure of MilB Streptomyces rimofaciens CMP N-glycosidase | | 分子名称: | CMP/hydroxymethyl CMP hydrolase, SULFATE ION | | 著者 | Sikowitz, M.D, Cooper, L.E, Begley, T.P, Kaminski, P.A, Ealick, S.E. | | 登録日 | 2013-02-27 | | 公開日 | 2013-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Biochemistry, 52, 2013
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3EPO
 | | Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P | | 分子名称: | (4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL DIHYDROGEN PHOSPHATE, Thiamine biosynthesis protein thiC | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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4JEN
 | | Structure of Clostridium botulinum CMP N-glycosidase, BcmB | | 分子名称: | CMP N-GLYCOSIDASE, PHOSPHATE ION | | 著者 | Sikowitz, M.D, Cooper, L.E, Begley, T.P, Kaminski, P.A, Ealick, S.E. | | 登録日 | 2013-02-27 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Biochemistry, 52, 2013
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3DWG
 | | Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis | | 分子名称: | 9.5 kDa culture filtrate antigen cfp10A, Cysteine synthase B, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Jurgenson, C.T, Burns, K.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-07-22 | | 公開日 | 2008-09-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis.
Biochemistry, 47, 2008
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4JEM
 | | Crystal structure of MilB complexed with cytidine 5'-monophosphate | | 分子名称: | CMP/hydroxymethyl CMP hydrolase, CYTIDINE-5'-MONOPHOSPHATE | | 著者 | Sikowitz, M.D, Cooper, L.E, Begley, T.P, Kaminski, P.A, Ealick, S.E. | | 登録日 | 2013-02-27 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.553 Å) | | 主引用文献 | Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Biochemistry, 52, 2013
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3DWI
 | | Crystal structure of Mycobacterium tuberculosis CysM, the cysteine synthase B | | 分子名称: | Cysteine synthase B, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | 著者 | Jurgenson, C.T, Burns, K.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-07-22 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis.
Biochemistry, 47, 2008
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3EPN
 | | Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide | | 分子名称: | 1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole, Thiamine biosynthesis protein thiC | | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
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1F0Z
 | | SOLUTION STRUCTURE OF THIS, THE SULFUR CARRIER PROTEIN IN E.COLI THIAMIN BIOSYNTHESIS | | 分子名称: | THIS PROTEIN | | 著者 | Wang, C, Xi, J, Begley, T.P, Nicholson, L.K. | | 登録日 | 2000-05-17 | | 公開日 | 2001-01-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of ThiS and implications for the evolutionary roots of ubiquitin.
Nat.Struct.Biol., 8, 2001
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3KXP
 | | Crystal Structure of E-2-(Acetamidomethylene)succinate Hydrolase | | 分子名称: | Alpha-(N-acetylaminomethylene)succinic acid hydrolase, CHLORIDE ION | | 著者 | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-12-03 | | 公開日 | 2010-02-09 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structure determination and characterization of the vitamin B(6) degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase.
Biochemistry, 49, 2010
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3GMC
 | | Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase with substrate bound | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxy-6-methylpyridine-3-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-03-13 | | 公開日 | 2009-04-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
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3GMB
 | | Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-03-13 | | 公開日 | 2009-04-14 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
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3C9U
 | | AaThiL complexed with ADP and TPP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | | 著者 | McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-02-18 | | 公開日 | 2008-03-18 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
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3C9R
 | | AaThiL complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Thiamine monophosphate kinase | | 著者 | McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-02-18 | | 公開日 | 2008-03-18 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
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3KVV
 | | Trapping of an oxocarbenium ion intermediate in UP crystals | | 分子名称: | 1,4-anhydro-D-erythro-pent-1-enitol, 5-FLUOROURACIL, SULFATE ION, ... | | 著者 | Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-11-30 | | 公開日 | 2010-04-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
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