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PDB: 128 件

1EKQ
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CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN R3 SPACE GROUP
分子名称: HYDROXYETHYLTHIAZOLE KINASE
著者Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E.
登録日2000-03-09
公開日2000-08-09
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
1F0Z
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SOLUTION STRUCTURE OF THIS, THE SULFUR CARRIER PROTEIN IN E.COLI THIAMIN BIOSYNTHESIS
分子名称: THIS PROTEIN
著者Wang, C, Xi, J, Begley, T.P, Nicholson, L.K.
登録日2000-05-17
公開日2001-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of ThiS and implications for the evolutionary roots of ubiquitin.
Nat.Struct.Biol., 8, 2001
3RP6
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Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase
著者Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E.
登録日2011-04-26
公開日2012-05-16
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
3RM5
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Structure of Trifunctional THI20 from Yeast
分子名称: Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20, SULFATE ION
著者French, J.B, Begley, T.P, Ealick, S.E.
登録日2011-04-20
公開日2011-09-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structure of trifunctional THI20 from yeast.
Acta Crystallogr.,Sect.D, 67, 2011
3RP7
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Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD and uric acid
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, URIC ACID, flavoprotein monooxygenase
著者Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E.
登録日2011-04-26
公開日2012-05-16
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (2.042 Å)
主引用文献Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
3KVV
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Trapping of an oxocarbenium ion intermediate in UP crystals
分子名称: 1,4-anhydro-D-erythro-pent-1-enitol, 5-FLUOROURACIL, SULFATE ION, ...
著者Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E.
登録日2009-11-30
公開日2010-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3RP8
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Crystal Structure of Klebsiella pneumoniae R204Q HpxO complexed with FAD
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase
著者Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E.
登録日2011-04-26
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
3QH2
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Crystal structure of TenI from Bacillus subtilis complexed with product cThz-P
分子名称: 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, Regulatory protein tenI, SULFATE ION
著者Han, Y, Zhang, Y, Hazra, A, Chatterjee, A, Lai, R, Begley, T.P, Ealick, S.E.
登録日2011-01-25
公開日2011-05-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase.
J.Am.Chem.Soc., 133, 2011
3IX1
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Periplasmic N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein from Bacillus halodurans
分子名称: N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamide, N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein
著者Bale, S, Rajashankar, K.R, Perry, K, Begley, T.P, Ealick, S.E.
登録日2009-09-03
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献HMP Binding Protein ThiY and HMP-P Synthase THI5 Are Structural Homologues.
Biochemistry, 49, 2010
4ESX
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Crystal structure of C. albicans Thi5 complexed with PLP
分子名称: Pyrimidine biosynthesis enzyme THI13
著者Huang, S, Fenwick, M.K, Zhang, Y, Lai, R, Hazra, A, Rajashankar, K, Philmus, B, Kinsland, C, Sanders, J, Begley, T.P, Ealick, S.E.
登録日2012-04-23
公開日2012-09-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
1XOB
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THIOREDOXIN (REDUCED DITHIO FORM), NMR, 20 STRUCTURES
分子名称: THIOREDOXIN
著者Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
登録日1995-11-28
公開日1996-06-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
4ESW
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Crystal structure of C. albicans Thi5 H66G mutant
分子名称: CITRIC ACID, Pyrimidine biosynthesis enzyme THI13
著者Fenwick, M.K, Huang, S, Zhang, Y, Lai, R, Hazra, A, Rajashankar, K, Philmus, B, Kinsland, C, Sanders, J, Begley, T.P, Ealick, S.E.
登録日2012-04-23
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
1YAD
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Structure of TenI from Bacillus subtilis
分子名称: Regulatory protein tenI, SULFATE ION, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM
著者Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E.
登録日2004-12-17
公開日2005-02-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
1YFU
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, CHLORIDE ION, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
1YAK
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Complex of Bacillus subtilis TenA with 4-amino-2-methyl-5-hydroxymethylpyrimidine
分子名称: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, Transcriptional activator tenA
著者Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E.
登録日2004-12-17
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
1XOA
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THIOREDOXIN (OXIDIZED DISULFIDE FORM), NMR, 20 STRUCTURES
分子名称: THIOREDOXIN
著者Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
登録日1995-11-28
公開日1996-06-10
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
1YFW
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and O2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
1YFX
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and NO
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
1YFY
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 3-hydroxyanthranilic acid
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate-3,4-dioxygenase, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
1YAF
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Structure of TenA from Bacillus subtilis
分子名称: Transcriptional activator tenA
著者Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E.
登録日2004-12-17
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
2B5H
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1.5 A Resolution Crystal Structure of Recombinant R. Norvegicus Cysteine Dioxygenase
分子名称: Cysteine dioxygenase type I, FE (III) ION
著者Simmons, C.R, Liu, Q, Huang, Q, Hao, Q, Begley, T.P, Karplus, P.A, Stipanuk, M.H.
登録日2005-09-28
公開日2006-04-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Mammalian Cysteine Dioxygenase: A NOVEL MONONUCLEAR IRON CENTER FOR CYSTEINE THIOL OXIDATION.
J.Biol.Chem., 281, 2006
3GMC
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Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase with substrate bound
分子名称: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxy-6-methylpyridine-3-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE
著者McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E.
登録日2009-03-13
公開日2009-04-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
3GMB
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Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase
分子名称: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E.
登録日2009-03-13
公開日2009-04-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications.
Biochemistry, 48, 2009
3KUK
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Trapping of an oxocarbenium ion intermediate in UP crystals
分子名称: 2'-DEOXYURIDINE, SULFATE ION, Uridine phosphorylase
著者Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E.
登録日2009-11-27
公開日2010-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.783 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KVY
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Trapping of an oxocarbenium ion intermediate in UP crystals
分子名称: 1,4-anhydro-D-erythro-pent-1-enitol, SULFATE ION, URACIL, ...
著者Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E.
登録日2009-11-30
公開日2010-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010

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