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PDB: 4 件

4CKJ
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BU of 4ckj by Molmil
Crystal structure of RET tyrosine kinase domain bound to adenosine
分子名称: ADENOSINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者Plaza-Menacho, I, Barnouin, K, Goodman, K, Martinez-Torres, R.J, Borg, A, Murray-Rust, J, Mouilleron, S, Knowles, P, McDonald, N.Q.
登録日2014-01-06
公開日2014-03-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Oncogenic RET kinase domain mutations perturb the autophosphorylation trajectory by enhancing substrate presentation in trans.
Mol. Cell, 53, 2014
4CKI
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BU of 4cki by Molmil
Crystal Structure of oncogenic RET tyrosine kinase M918T bound to adenosine
分子名称: ADENOSINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者Plaza-Menacho, I, Barnouin, K, Goodman, K, Martinez-Torres, R.J, Borg, A, Murray-Rust, J, Mouilleron, S, Knowles, P, McDonald, N.Q.
登録日2014-01-06
公開日2014-03-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.116 Å)
主引用文献Oncogenic RET kinase domain mutations perturb the autophosphorylation trajectory by enhancing substrate presentation in trans.
Mol. Cell, 53, 2014
5FM2
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BU of 5fm2 by Molmil
Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment
分子名称: 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者Plaza-Menacho, I, Barnouin, K, Barry, R, Borg, A, Orme, M, Mouilleron, S, Martinez-Torres, R.J, Meier, P, McDonald, N.Q.
登録日2015-10-30
公開日2016-12-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.
Cell Rep, 17, 2016
5FM3
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BU of 5fm3 by Molmil
Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment
分子名称: 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者Plaza-Menacho, I, Barnouin, K, Barry, R, Borg, A, Orme, M, Mouilleron, S, Martinez-Torres, R.J, Meier, P, McDonald, N.Q.
登録日2015-10-30
公開日2016-12-28
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.
Cell Rep, 17, 2016

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件を2024-11-06に公開中

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