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PDB: 4 件

7ZYI
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BU of 7zyi by Molmil
Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody
分子名称: CHOLESTEROL, GLYCOCHENODEOXYCHOLIC ACID, Nanobody, ...
著者Liu, H, Irobalieva, R.N, Bang-Sorensen, R, Nosol, K, Mukherjee, S, Agrawal, P, Stieger, B, Kossiakoff, A.A, Locher, K.P.
登録日2022-05-24
公開日2022-07-13
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
Cell Res., 32, 2022
8PM6
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BU of 8pm6 by Molmil
Human bile salt export pump (BSEP) in complex with inhibitor GBM in nanodiscs
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Bile salt export pump, CHOLESTEROL
著者Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P.
登録日2023-06-28
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023
8PMJ
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Vanadate-trapped BSEP in nanodiscs
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, ...
著者Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P.
登録日2023-06-28
公開日2023-11-29
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023
8PMD
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BU of 8pmd by Molmil
Nucleotide-bound BSEP in nanodiscs
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, MAGNESIUM ION
著者Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P.
登録日2023-06-28
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023

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件を2024-07-24に公開中

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