7LFQ
 
 | | Pyrococcus RNA ligase | | 分子名称: | DNA (5'-D(*AP*TP*GP*TP*CP*C)-3'), POTASSIUM ION, RNA-splicing ligase RtcB, ... | | 著者 | Goldgur, Y, Shuman, S, Banerjee, A. | | 登録日 | 2021-01-18 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of 3'-PO 4 /5'-OH RNA ligase RtcB in complex with a 5'-OH oligonucleotide.
Rna, 27, 2021
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6BMM
 | | Structure of human DHHC20 palmitoyltransferase, space group P21 | | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,5S)-hexane-2,5-diol, PHOSPHATE ION, ... | | 著者 | Rana, M.S, Lee, C.-J, Banerjee, A. | | 登録日 | 2017-11-15 | | 公開日 | 2018-01-24 | | 最終更新日 | 2018-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Fatty acyl recognition and transfer by an integral membraneS-acyltransferase.
Science, 359, 2018
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8A9Z
 | | Tubulin-[1,2]oxazoloisoindole-2e complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7-[(3,5-dimethoxyphenyl)methyl]pyrrolo[3,4-g][1,2]benzoxazole, CALCIUM ION, ... | | 著者 | Prota, A.E, Abel, A.-C, Steinmetz, M.O, Barraja, P, Montalbano, A, Spano, V. | | 登録日 | 2022-06-29 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | | 主引用文献 | Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas.
Eur.J.Med.Chem., 243, 2022
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6U05
 | | Crystal Structure of Fungal RNA Kinase | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | | 登録日 | 2019-08-13 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor.
Nucleic Acids Res., 47, 2019
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6BK9
 | | Crystal Structure of Squid Arrestin | | 分子名称: | CHLORIDE ION, Visual arrestin | | 著者 | Eger, B.T, Bandyopadhyay, A, Yedidi, R.S, Ernst, O.P. | | 登録日 | 2017-11-08 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.00005579 Å) | | 主引用文献 | A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin.
J. Mol. Biol., 430, 2018
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2LS5
 | | Solution structure of a putative protein disulfide isomerase from Bacteroides thetaiotaomicron | | 分子名称: | Uncharacterized protein | | 著者 | Harris, R, Bandaranayake, A.D, Banu, R, Bonanno, J.B, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chaparro, R, Evans, B, Garforth, S, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Lim, S, Love, J, Matikainen, B, Patel, H, Seidel, R.D, Smith, B, Stead, M, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-04-20 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a putative protein disulfide isomerase from Bacteroides thetaiotaomicron
To be Published
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6E3A
 | | tRNA 2'-phosphotransferase | | 分子名称: | COENZYME A, Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | | 登録日 | 2018-07-13 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation.
Nat Commun, 10, 2019
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5CLM
 | | 1,4-Oxazine BACE1 inhibitors | | 分子名称: | Beta-secretase 1, CHLORIDE ION, IODIDE ION, ... | | 著者 | Rombouts, F, Tresadern, G, Delgado, O, Martinez Lamenca, C, Van Gool, M, Garcia-Molina, A, Alonso De Diego, S, Oehlrich, D, Prokopcova, H, Alonso, J.M, Austin, N, Borghys, H, Van Brandt, S, Surkyn, M, De Cleyn, M, Vos, A, Alexander, R, MacDonald, G, Moechars, D, Trabanco, A, Gijsen, H. | | 登録日 | 2015-07-16 | | 公開日 | 2015-09-30 | | 最終更新日 | 2015-11-04 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | 1,4-Oxazine beta-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads.
J.Med.Chem., 58, 2015
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1BE6
 | | TRANS-CINNAMOYL-SUBTILISIN IN ANHYDROUS ACETONITRILE | | 分子名称: | ACETONITRILE, CALCIUM ION, PHENYLETHYLENECARBOXYLIC ACID, ... | | 著者 | Schmitke, J.L, Stern, L.J, Klibanov, A.M. | | 登録日 | 1998-05-20 | | 公開日 | 1998-10-14 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water.
Proc.Natl.Acad.Sci.USA, 95, 1998
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6BMN
 | | Structure of human DHHC20 palmitoyltransferase, space group P63 | | 分子名称: | 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ZINC ION, ... | | 著者 | Rana, M.S, Lee, C.-J, Banerjee, A. | | 登録日 | 2017-11-15 | | 公開日 | 2018-01-24 | | 最終更新日 | 2018-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Fatty acyl recognition and transfer by an integral membraneS-acyltransferase.
Science, 359, 2018
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6BML
 | | Structure of human DHHC20 palmitoyltransferase, irreversibly inhibited by 2-bromopalmitate | | 分子名称: | 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, PALMITIC ACID, PHOSPHATE ION, ... | | 著者 | Rana, M.S, Lee, C.-J, Banerjee, A. | | 登録日 | 2017-11-15 | | 公開日 | 2018-01-24 | | 最終更新日 | 2018-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Fatty acyl recognition and transfer by an integral membraneS-acyltransferase.
Science, 359, 2018
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5KZE
 | | N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus | | 分子名称: | GLYCEROL, N-acetylneuraminate lyase, SULFATE ION | | 著者 | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | | 登録日 | 2016-07-25 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.
FEBS Lett., 590, 2016
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7KHM
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5KZD
 | | N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus with bound sialic acid alditol | | 分子名称: | (2~{S},4~{S},5~{R},6~{R},7~{S},8~{R})-5-acetamido-2,4,6,7,8,9-hexakis(oxidanyl)nonanoic acid, N-acetylneuraminate lyase | | 著者 | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | | 登録日 | 2016-07-25 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.334 Å) | | 主引用文献 | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.
FEBS Lett., 590, 2016
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6EDE
 | | tRNA 2'-phosphotransferase | | 分子名称: | Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | | 登録日 | 2018-08-09 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.553 Å) | | 主引用文献 | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation.
Nat Commun, 10, 2019
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1AF4
 | | CRYSTAL STRUCTURE OF SUBTILISIN CARLSBERG IN ANHYDROUS DIOXANE | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, CALCIUM ION, SUBTILISIN CARLSBERG | | 著者 | Schmitke, J.L, Stern, L.J, Klibanov, A.M. | | 登録日 | 1997-03-21 | | 公開日 | 1997-06-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of subtilisin Carlsberg in anhydrous dioxane and its comparison with those in water and acetonitrile.
Proc.Natl.Acad.Sci.USA, 94, 1997
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4JTA
 | | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | | 著者 | MacKinnon, R, Banerjee, A, Lee, A, Campbell, E. | | 登録日 | 2013-03-23 | | 公開日 | 2013-06-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
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1BFK
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5VJV
 | | Rhizobiales-like phosphatase 2 | | 分子名称: | PHOSPHATE ION, Rhizobiales-like phosphatase 2, ZINC ION | | 著者 | Ng, K.K.S, Labandera, A, Moorhead, G. | | 登録日 | 2017-04-20 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for the preference of the Arabidopsis thalianaphosphatase RLPH2 for tyrosine-phosphorylated substrates.
Sci Signal, 11, 2018
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2VTF
 | | X-ray crystal structure of the Endo-beta-N-acetylglucosaminidase from Arthrobacter protophormiae E173Q mutant reveals a TIM barrel catalytic domain and two ancillary domains | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ENDO-BETA-N-ACETYLGLUCOSAMINIDASE, TRIETHYLENE GLYCOL | | 著者 | Ling, Z, Bingham, R.J, Suits, M.D.L, Moir, J.W.B, Fairbanks, A.J, Taylor, E.J. | | 登録日 | 2008-05-14 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | The X-Ray Crystal Structure of an Arthrobacter Protophormiae Endo-Beta-N-Acetylglucosaminidase Reveals a (Beta/Alpha)(8) Catalytic Domain, Two Ancillary Domains and Active Site Residues Key for Transglycosylation Activity.
J.Mol.Biol., 389, 2009
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1BQB
 | | AUREOLYSIN, STAPHYLOCOCCUS AUREUS METALLOPROTEINASE | | 分子名称: | CALCIUM ION, PROTEIN (AUREOLYSIN), ZINC ION | | 著者 | Medrano, F.J, Banbula, A, Potempa, J, Travis, J, Bode, W. | | 登録日 | 1998-07-14 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution.
Structure, 6, 1998
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7KW9
 | | NMR Structure of a tRNA 2'-phosphotransferase from Runella slithyformis in complex with NAD+ | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, tRNA 2'-phosphotransferase | | 著者 | Alphonse, S, Dantuluri, S, Banerjee, A, Shuman, S, Ghose, R. | | 登録日 | 2020-11-30 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity.
Nucleic Acids Res., 49, 2021
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5VJW
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2YLL
 | | Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis | | 分子名称: | 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BETA-N-ACETYLHEXOSAMINIDASE, ... | | 著者 | Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. | | 登録日 | 2011-06-02 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
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1XFD
 | | Structure of a human A-type Potassium Channel Accelerating factor DPPX, a member of the dipeptidyl aminopeptidase family | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl aminopeptidase-like protein 6, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Strop, P, Bankovich, A.J, Hansen, K.C, Garcia, K.C, Brunger, A.T. | | 登録日 | 2004-09-14 | | 公開日 | 2004-10-26 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family
J.Mol.Biol., 343, 2004
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