PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure of the Fab fragment of necitumumab (Fab11F8) in complex with domain III from a cetuximab resistant variant of EGFR (sEGFRd3-S468R)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:	Ferguson, K.M, Bagchi, A.
Deposit date:	2017-09-23
Release date:	2017-12-06
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance. Mol. Cancer Ther., 17, 2018

Crystal structure of nanobody/VHH domain of 34E5 in complex with the extracellular region of the epidermal growth factor variant III (EGFRvIII)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:	Stayrook, S.E, Ferguson, K.M, Bagchi, A.
Deposit date:	2023-10-15
Release date:	2024-06-19
Method:	X-RAY DIFFRACTION (2.94 Å)
Cite:	Structural insights into the role and targeting of EGFRvIII Structure, 2024