5OPY
 
 | | Crystal structure of anti-alphaVbeta3 integrin Fab LM609 | | 分子名称: | Heavy chain of LM609 Fab (antigen-binding fragment), Light chain of LM609 Fab (antigen-binding fragment) | | 著者 | Backovic, M, Veesler, D, Borst, A.J, James, Z.M, Zagotta, W, Ginsberg, M, Rey, F.A, DiMaio, F. | | 登録日 | 2017-08-10 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
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2XQY
 | | CRYSTAL STRUCTURE OF PSEUDORABIES CORE FRAGMENT OF GLYCOPROTEIN H IN COMPLEX WITH FAB D6.3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A13-D6.3 MONOCLONAL ANTIBODY, ... | | 著者 | Backovic, M, Dubois, R, Cockburn, J, Sharff, A, Vaney, M, Granzow, H, Klupp, B, Bricogne, G, Mettenleiter, T, Rey, F. | | 登録日 | 2010-09-08 | | 公開日 | 2010-12-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of a Core Fragment of Glycoprotein H from Pseudorabies Virus in Complex with Antibody.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6ESC
 | | Crystal structure of Pseudorabies virus glycoprotein B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, GLYCEROL | | 著者 | Backovic, M, Vaney, M.C, Rey, F.A, Haouz, A. | | 登録日 | 2017-10-20 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-Function Dissection of Pseudorabies Virus Glycoprotein B Fusion Loops.
J.Virol., 92, 2018
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3FVC
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8AEZ
 | | X-ray structure of the deglycosylated receptor binding domain of Env glycoprotein of Simian Foamy virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp130, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Backovic, M. | | 登録日 | 2022-07-14 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-03-15 | | 実験手法 | X-RAY DIFFRACTION (2.574 Å) | | 主引用文献 | The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells.
Nat Commun, 14, 2023
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8AIC
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6Z9M
 | | Pseudoatomic model of the pre-fusion conformation of glycoprotein B of Herpes simplex virus 1 | | 分子名称: | Envelope glycoprotein B | | 著者 | Vollmer, B, Prazak, V, Vasishtan, D, Jefferys, E.E, Hernandez-Duran, A, Vallbracht, M, Klupp, B, Mettenleiter, T.C, Backovic, M, Rey, F.A, Topf, M, Gruenewald, K. | | 登録日 | 2020-06-04 | | 公開日 | 2020-10-07 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | The prefusion structure of herpes simplex virus glycoprotein B.
Sci Adv, 6, 2020
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6RX1
 | | Crystal structure of human syncytin 1 in post-fusion conformation | | 分子名称: | CHLORIDE ION, GLYCEROL, Syncytin-1 | | 著者 | Ruigrok, K, Backovic, M, Vaney, M.C, Rey, F.A. | | 登録日 | 2019-06-07 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
J.Mol.Biol., 431, 2019
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6RX3
 | | Crystal structure of human syncytin 2 in post-fusion conformation | | 分子名称: | CHLORIDE ION, Syncytin-2 | | 著者 | Ruigrok, K, Backovic, M, Vaney, M.C, Rey, F.A. | | 登録日 | 2019-06-07 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
J.Mol.Biol., 431, 2019
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6AVQ
 | | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha-V beta-3 Integrin via Steric Hindrance | | 分子名称: | Integrin alpha-V, Integrin beta-3, LM609 Fab heavy chain, ... | | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | | 登録日 | 2017-09-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (35 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
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6AVR
 | | Human alpha-V beta-3 Integrin (intermediate conformation) in complex with the therapeutic antibody LM609 | | 分子名称: | Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ... | | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | | 登録日 | 2017-09-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (35 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
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6AVU
 | | Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609 | | 分子名称: | Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ... | | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | | 登録日 | 2017-09-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (35 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
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7B7N
 | | Human herpesvirus-8 gH/gL in complex with EphA2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Pederzoli, R, Guardado-Calvo, P, Rey, F.A, Backovic, M. | | 登録日 | 2020-12-11 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.
Plos Biol., 19, 2021
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