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PDB: 23 件

3LXG
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Crystal structure of rat phosphodiesterase 10A in complex with ligand WEB-3
分子名称: 2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazine, MAGNESIUM ION, ZINC ION, ...
著者Mosbacher, T, Jestel, A, Steinbacher, S.
登録日2010-02-25
公開日2010-05-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of imidazo[1,5-a]pyrido[3,2-e]pyrazines as a new class of phosphodiesterase 10A inhibitiors.
J.Med.Chem., 53, 2010
6GVB
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Crystal structure of Cutibacterium acnes exo-beta-1,4-mannosidase
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, exo-beta-1,4-mannosidase
著者Reichenbach, T, Divne, C.
登録日2018-06-20
公開日2019-07-03
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and biochemical characterization of the Cutibacterium acnes exo-beta-1,4-mannosidase that targets the N-glycan core of host glycoproteins.
Plos One, 13, 2018
3FWO
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The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin
分子名称: (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA
著者Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A.
登録日2009-01-19
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin
Biotechnologia, 1, 2009
2AG0
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Crystal structure of Benzaldehyde lyase (BAL)- native
分子名称: MAGNESIUM ION, THIAMINE DIPHOSPHATE, benzaldehyde lyase
著者Mosbacher, T.G, Mueller, M, Schulz, G.E.
登録日2005-07-26
公開日2006-01-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens
Febs J., 272, 2005
2AG1
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Crystal structure of Benzaldehyde lyase (BAL)- SeMet
分子名称: MAGNESIUM ION, THIAMINE DIPHOSPHATE, benzaldehyde lyase
著者Mosbacher, T.G, Mueller, M, Schulz, G.E.
登録日2005-07-26
公開日2006-01-24
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens
Febs J., 272, 2005
1O9G
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rRNA methyltransferase aviRa from Streptomyces viridochromogenes at 1.5A
分子名称: RRNA METHYLTRANSFERASE
著者Mosbacher, T.G, Schulz, G.E.
登録日2002-12-13
公開日2003-05-16
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of the Avilamycin Resistance-Conferring Methyltransferase Avira from Streptomyces Viridochromogenes
J.Mol.Biol., 329, 2003
1O9H
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rRNA methyltransferase aviRa from Streptomyces viridochromogenes at 2.4A
分子名称: RRNA METHYLTRANSFERASE
著者Mosbacher, T.G, Schulz, G.E.
登録日2002-12-13
公開日2003-05-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Avilamycin Resistance-Conferring Methyltransferase Avira from Streptomyces Viridochromogenes
J.Mol.Biol., 329, 2003
1X7O
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Crystal structure of the SpoU Methyltransferase AviRb from Streptomyces viridochromogenes
分子名称: rRNA methyltransferase
著者Mosbacher, T.G, Bechthold, A, Schulz, G.E.
登録日2004-08-16
公開日2005-01-25
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes
J.Mol.Biol., 345, 2005
1X7P
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Crystal structure of the SpoU Methyltransferase AviRb from Streptomyces viridochromogenes in complex with the cofactor AdoMet
分子名称: S-ADENOSYLMETHIONINE, rRNA methyltransferase
著者Mosbacher, T.G, Bechthold, A, Schulz, G.E.
登録日2004-08-16
公開日2005-01-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes
J.Mol.Biol., 345, 2005
6SLO
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Crystal structure of PUF60 UHM domain in complex with 7,8 dimethoxyperphenazine
分子名称: 2-[4-[3-(8-chloranyl-2,3-dimethoxy-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol, MAGNESIUM ION, Thioredoxin,Poly(U)-binding-splicing factor PUF60
著者Jagtap, P.K.A, Kubelka, T, Bach, T, Sattler, M.
登録日2019-08-20
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
Nat Commun, 11, 2020
6ZB9
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Exo-beta-1,3-glucanase from moose rumen microbiome, wild type
分子名称: Exo-beta-1,3-glucanase
著者Kalyani, D.C, Reichenbach, T, Aspeborg, H, Divne, C.
登録日2020-06-08
公開日2021-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A homodimeric bacterial exo-beta-1,3-glucanase derived from moose rumen microbiome shows a structural framework similar to yeast exo-beta-1,3-glucanases.
Enzyme.Microb.Technol., 143, 2021
6ZB8
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Exo-beta-1,3-glucanase from moose rumen microbiome, active site mutant E167Q/E295Q
分子名称: Exo-beta-1,3-glucanase variant E167Q/E295Q, POLYETHYLENE GLYCOL (N=34)
著者Kalyani, D.C, Reichenbach, T, Aspeborg, H, Divne, C.
登録日2020-06-08
公開日2021-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A homodimeric bacterial exo-beta-1,3-glucanase derived from moose rumen microbiome shows a structural framework similar to yeast exo-beta-1,3-glucanases.
Enzyme.Microb.Technol., 143, 2021
5MM0
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Dolichyl phosphate mannose synthase in complex with GDP-mannose and Mn2+ (donor complex)
分子名称: CHLORIDE ION, Dolichol monophosphate mannose synthase, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ...
著者Gandini, R, Reichenbach, T, Tan, T.C, Divne, C.
登録日2016-12-08
公開日2017-08-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for dolichylphosphate mannose biosynthesis.
Nat Commun, 8, 2017
5MM1
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Dolichyl phosphate mannose synthase in complex with GDP and dolichyl phosphate mannose
分子名称: Dolichol monophosphate mannose synthase, GUANOSINE-5'-DIPHOSPHATE, dolichyl phosphate mannose
著者Gandini, R, Reichenbach, T, Tan, T.C, Divne, C.
登録日2016-12-08
公開日2017-08-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for dolichylphosphate mannose biosynthesis.
Nat Commun, 8, 2017
5MLZ
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Dolichyl phosphate mannose synthase in complex with GDP and Mg2+
分子名称: CHLORIDE ION, Dolichol monophosphate mannose synthase, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gandini, R, Reichenbach, T, Tan, T.C, Divne, C.
登録日2016-12-08
公開日2017-08-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for dolichylphosphate mannose biosynthesis.
Nat Commun, 8, 2017
7BOB
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Exo-beta-1,4-mannosidase Op5Man5 from Opitutaceae bacterium strain TAV5
分子名称: Endo-beta-mannanase
著者Kalyani, D.C, Reichenbach, T, Keskitalo, M.M, Conrad, J, Aspeborg, H, Divne, C.
登録日2021-01-24
公開日2021-07-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a homotrimeric verrucomicrobial exo - beta -1,4-mannosidase active in the hindgut of the wood-feeding termite Reticulitermes flavipes .
J Struct Biol X, 5, 2021
7Z2X
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Wild-type ferulic acid esterase from Lactobacillus buchneri
分子名称: Ferulic acid esterase
著者Mogodiniyai, K.K, Reichenbach, T, Kalyani, D.C, Keskitalo, M.M, Divne, C.
登録日2022-03-01
公開日2022-11-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state.
Front Microbiol, 13, 2022
7Z2U
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Wild-type ferulic acid esterase from Lactobacillus buchneri in complex with ferulate
分子名称: 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, CALCIUM ION, Ferulic acid esterase
著者Mogodiniyai, K.K, Reichenbach, T, Kalyani, D.C, Keskitalo, M.M, Divne, C.
登録日2022-02-28
公開日2022-11-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state.
Front Microbiol, 13, 2022
7Z2V
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Ferulic acid esterase variant S114A from Lactobacillus buchneri
分子名称: ACETATE ION, CALCIUM ION, Ferulic acid esterase
著者Mogodiniyai, K.K, Reichenbach, T, Kalyani, D.C, Keskitalo, M.M, Divne, C.
登録日2022-02-28
公開日2022-11-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state.
Front Microbiol, 13, 2022
1EPU
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X-RAY crystal structure of neuronal SEC1 from squid
分子名称: S-SEC1
著者Bracher, A, Perrakis, A, Dresbach, T, Betz, H, Weissenhorn, W.
登録日2000-03-29
公開日2000-08-09
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.
Structure Fold.Des., 8, 2000
3SNL
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Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors
分子名称: 6-chloro-3,4-dimethyl-1-(3-methylpyridin-4-yl)-8-(trifluoromethyl)imidazo[1,5-a]quinoxaline, MAGNESIUM ION, ZINC ION, ...
著者Malamas, M.S, Ni, Y, Erdei, J, Stange, H, Schindler, R, Lankau, H.-J, Grunwald, C, Fan, K.Y, Parris, K.D, Langen, B, Egerland, U, Hage, T, Marquis, K.L, Grauer, S, Brennan, J, Navarra, R, Graf, R, Harrison, B.L, Robichaud, A, Kronbach, T, Pangalos, M, Hofgen, N, Brandon, N.J.
登録日2011-06-29
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors.
J.Med.Chem., 54, 2011
3SNI
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Highly Potent, Selective, and Orally Active Phosphodiestarase 10A Inhibitors
分子名称: 2-methoxy-6,7-dimethyl-9-(4-methylpyridin-3-yl)imidazo[1,5-a]pyrido[3,2-e]pyrazine, CHLORIDE ION, MAGNESIUM ION, ...
著者Malamas, M.S, Ni, Y, Erdei, J, Stange, H, Schindler, R, Lankau, H.-J, Grunwald, C, Fan, K.Y, Parris, K.D, Langen, B, Egerland, U, Hage, T, Marquis, K.L, Grauer, S, Brennan, J, Navarra, R, Graf, R, Harrison, B.L, Robichaud, A, Kronbach, T, Pangalos, M, Hofgen, N, Brandon, N.J.
登録日2011-06-29
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors.
J.Med.Chem., 54, 2011
1OND
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TROLEANDOMYCIN MACROLIDE ANTIBIOTIC
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L22, 50S ribosomal protein L32, ...
著者Berisio, R, Schluenzen, F, Harms, J, Bashan, A, Auerbach, T, Baram, D, Yonath, A.
登録日2003-02-27
公開日2003-04-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural insight into the role of the ribosomal tunnel in cellular regulation
Nat.Struct.Biol., 10, 2003

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