6LHM
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![BU of 6lhm by Molmil](/molmil-images/mine/6lhm) | Structure of human PYCR2 | Descriptor: | Pyrroline-5-carboxylate reductase 2 | Authors: | Baburajendran, N. | Deposit date: | 2019-12-09 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2. Neuron, 107, 2020
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3KMP
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![BU of 3kmp by Molmil](/molmil-images/mine/3kmp) | Crystal Structure of SMAD1-MH1/DNA complex | Descriptor: | 5'-D(P*AP*TP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*AP*TP*A)-3', 5'-D(P*GP*TP*AP*TP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*A)-3', GLYCEROL, ... | Authors: | Baburajendran, N, Palasingam, P, Narasimhan, K, Jauch, R, Kolatkar, P.R. | Deposit date: | 2009-11-11 | Release date: | 2010-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors. Nucleic Acids Res., 38, 2010
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3QSV
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![BU of 3qsv by Molmil](/molmil-images/mine/3qsv) | |
5ZJQ
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![BU of 5zjq by Molmil](/molmil-images/mine/5zjq) | Structure of AbdB/Exd complex bound to a 'Red14' DNA sequence | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... | Authors: | Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | Deposit date: | 2018-03-22 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.443 Å) | Cite: | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
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6ILZ
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![BU of 6ilz by Molmil](/molmil-images/mine/6ilz) | Crystal structure of PKCiota in complex with inhibitor | Descriptor: | 2-amino-5-[3-(piperazin-1-yl)phenyl]-N-(pyridin-4-yl)pyridine-3-carboxamide, Protein kinase C iota type | Authors: | Baburajendran, N, Hill, J. | Deposit date: | 2018-10-21 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.261 Å) | Cite: | Fragment-based Discovery of a Small-Molecule Protein Kinase C-iota Inhibitor Binding Post-kinase Domain Residues. Acs Med.Chem.Lett., 10, 2019
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6JLR
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![BU of 6jlr by Molmil](/molmil-images/mine/6jlr) | |
6IJL
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![BU of 6ijl by Molmil](/molmil-images/mine/6ijl) | |
5YJO
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![BU of 5yjo by Molmil](/molmil-images/mine/5yjo) | |
5XXD
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![BU of 5xxd by Molmil](/molmil-images/mine/5xxd) | |
5XXJ
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![BU of 5xxj by Molmil](/molmil-images/mine/5xxj) | |
5ZJS
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![BU of 5zjs by Molmil](/molmil-images/mine/5zjs) | Structure of AbdB/Exd complex bound to a 'Blue14' DNA sequence | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... | Authors: | Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | Deposit date: | 2018-03-22 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.896 Å) | Cite: | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
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5XXG
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![BU of 5xxg by Molmil](/molmil-images/mine/5xxg) | |
7CC2
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![BU of 7cc2 by Molmil](/molmil-images/mine/7cc2) | |
4E6S
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![BU of 4e6s by Molmil](/molmil-images/mine/4e6s) | Crystal structure of the SCAN domain from mouse Zfp206 | Descriptor: | Zinc finger and SCAN domain-containing protein 10 | Authors: | Liang, Y, Choo, S.H, Rossbach, M, Baburajendran, N, Palasingam, P, Kolatkar, P.R. | Deposit date: | 2012-03-15 | Release date: | 2012-05-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal optimization and preliminary diffraction data analysis of the SCAN domain of Zfp206. Acta Crystallogr.,Sect.F, 68, 2012
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8JVE
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![BU of 8jve by Molmil](/molmil-images/mine/8jve) | Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer | Descriptor: | 1,2-ETHANEDIOL, 1-(3-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T | Authors: | Anantharajan, J, Baburajendran, N. | Deposit date: | 2023-06-28 | Release date: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer. Biochem.Biophys.Res.Commun., 689, 2023
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8JVL
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![BU of 8jvl by Molmil](/molmil-images/mine/8jvl) | Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer | Descriptor: | 1,2-ETHANEDIOL, 1-(4-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T | Authors: | Anantharajan, J, Baburajendran, N. | Deposit date: | 2023-06-28 | Release date: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer. Biochem.Biophys.Res.Commun., 689, 2023
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8JVD
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![BU of 8jvd by Molmil](/molmil-images/mine/8jvd) | |
8JUC
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![BU of 8juc by Molmil](/molmil-images/mine/8juc) | Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening | Descriptor: | 1,2-ETHANEDIOL, 7-methyl-2-(trifluoromethyl)-3~{H}-[1,2,4]triazolo[1,5-a]pyridin-5-one, Ubiquitin-conjugating enzyme E2 T | Authors: | Anantharajan, J, Baburajendran, N. | Deposit date: | 2023-06-26 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening. Protein Sci., 33, 2024
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7F8G
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![BU of 7f8g by Molmil](/molmil-images/mine/7f8g) | |
7F8H
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![BU of 7f8h by Molmil](/molmil-images/mine/7f8h) | |
7DT2
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![BU of 7dt2 by Molmil](/molmil-images/mine/7dt2) | |
7DXL
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![BU of 7dxl by Molmil](/molmil-images/mine/7dxl) | |
5ZJT
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![BU of 5zjt by Molmil](/molmil-images/mine/5zjt) | Structure of AbdB/Exd complex bound to a 'Black14' DNA sequence | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*AP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*TP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... | Authors: | Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | Deposit date: | 2018-03-22 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
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5ZJR
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![BU of 5zjr by Molmil](/molmil-images/mine/5zjr) | Structure of AbdB/Exd complex bound to a 'Magenta14' DNA sequence | Descriptor: | DNA (5'-D(*GP*TP*CP*GP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*AP*C)-3'), Homeobox protein abdominal-B, ... | Authors: | Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. | Deposit date: | 2018-03-22 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
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