4ZC7
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![BU of 4zc7 by Molmil](/molmil-images/mine/4zc7) | Paromomycin bound to a leishmanial ribosomal A-site | 分子名称: | PAROMOMYCIN, RNA duplex | 著者 | Shalev, M, Rozenberg, H, Jaffe, C.L, Adir, N, Baasov, T. | 登録日 | 2015-04-15 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.041 Å) | 主引用文献 | Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics. Nucleic Acids Res., 43, 2015
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1MQR
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![BU of 1mqr by Molmil](/molmil-images/mine/1mqr) | THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE (E386Q) FROM BACILLUS STEAROTHERMOPHILUS T-6 | 分子名称: | ALPHA-D-GLUCURONIDASE, GLYCEROL | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | 登録日 | 2002-09-17 | 公開日 | 2003-09-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
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1MQQ
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![BU of 1mqq by Molmil](/molmil-images/mine/1mqq) | THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE FROM BACILLUS STEAROTHERMOPHILUS T-1 COMPLEXED WITH GLUCURONIC ACID | 分子名称: | ALPHA-D-GLUCURONIDASE, GLYCEROL, alpha-D-glucopyranuronic acid | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | 登録日 | 2002-09-17 | 公開日 | 2003-09-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structures of Geobacillus stearothermophilus alpha-glucuronidase complexed with its substrate and products: mechanistic implications. J.Biol.Chem., 279, 2004
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1MQP
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![BU of 1mqp by Molmil](/molmil-images/mine/1mqp) | THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE FROM BACILLUS STEAROTHERMOPHILUS T-6 | 分子名称: | GLYCEROL, alpha-D-glucuronidase | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | 登録日 | 2002-09-17 | 公開日 | 2003-09-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of Geobacillus stearothermophilus alpha-glucuronidase complexed with its substrate and products: mechanistic implications. J.Biol.Chem., 279, 2004
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4RHH
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![BU of 4rhh by Molmil](/molmil-images/mine/4rhh) | Crystal structure of the catalytic mutant Xyn52B2-E335G, a GH52 Beta-D-xylosidase from Geobacillus stearothermophilus T6 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-xylosidase, CALCIUM ION | 著者 | Dann, R, Lansky, S, Lavid, N, Zehavi, A, Belakhov, V, Baasov, T, Manjasetty, B, Belrhali, H, Shoham, Y, Shoham, G. | 登録日 | 2014-10-02 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | To be published To be Published
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1G7V
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![BU of 1g7v by Molmil](/molmil-images/mine/1g7v) | CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, {[(2,2-DIHYDROXY-ETHYL)-(2,3,4,5-TETRAHYDROXY-6-PHOSPHONOOXY-HEXYL)-AMINO]-METHYL}-PHOSPHONIC ACID | 著者 | Asojo, O.A, Friedman, J.M, Belakhov, V, Shoham, Y, Adir, N, Baasov, T. | 登録日 | 2000-11-14 | 公開日 | 2001-05-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor. Biochemistry, 40, 2001
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1G7U
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![BU of 1g7u by Molmil](/molmil-images/mine/1g7u) | CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEX WITH SUBSTRATE PHOSPHOENOL PYRUVATE | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, PHOSPHOENOLPYRUVATE | 著者 | Asojo, O.A, Friedman, J.M, Belakhov, V, Shoham, Y, Adir, N, Baasov, T. | 登録日 | 2000-11-14 | 公開日 | 2001-05-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor. Biochemistry, 40, 2001
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4K31
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![BU of 4k31 by Molmil](/molmil-images/mine/4k31) | Crystal structure of apramycin bound to the leishmanial rRNA A-site | 分子名称: | APRAMYCIN, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*UP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | 著者 | Shalev, M, Kondo, J, Adir, N, Baasov, T. | 登録日 | 2013-04-10 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.415 Å) | 主引用文献 | Identification of the molecular attributes required for aminoglycoside activity against Leishmania. Proc.Natl.Acad.Sci.USA, 110, 2013
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4K32
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![BU of 4k32 by Molmil](/molmil-images/mine/4k32) | Crystal structure of geneticin bound to the leishmanial rRNA A-site | 分子名称: | GENETICIN, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*UP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | 著者 | Shalev, M, Kondo, J, Adir, N, Baasov, T. | 登録日 | 2013-04-10 | 公開日 | 2013-07-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification of the molecular attributes required for aminoglycoside activity against Leishmania. Proc.Natl.Acad.Sci.USA, 110, 2013
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1X8F
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![BU of 1x8f by Molmil](/molmil-images/mine/1x8f) | Crystal Structure Of apo-Kdo8P Synthase | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase | 著者 | Vainer, R, Belakhov, V, Rabkin, E, Baasov, T, Adir, N. | 登録日 | 2004-08-18 | 公開日 | 2005-07-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of Escherichia coli KDO8P Synthase Complexes Reveal the Source of Catalytic Irreversibility J.Mol.Biol., 351, 2005
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1X6U
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![BU of 1x6u by Molmil](/molmil-images/mine/1x6u) | KDO8P synthase in it's binary complex with the product KDO8P | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-8-O-phosphono-alpha-D-manno-oct-2-ulopyranosonic acid | 著者 | Vainer, R, Belakhov, V, Rabkin, E, Baasov, T, Adir, N. | 登録日 | 2004-08-12 | 公開日 | 2005-07-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Escherichia coli KDO8P Synthase Complexes Reveal the Source of Catalytic Irreversibility J.Mol.Biol., 351, 2005
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1K9D
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![BU of 1k9d by Molmil](/molmil-images/mine/1k9d) | The 1.7 A crystal structure of alpha-D-glucuronidase, a family-67 glycoside hydrolase from Bacillus stearothermophilus T-1 | 分子名称: | GLYCEROL, alpha-D-glucuronidase | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | 登録日 | 2001-10-29 | 公開日 | 2002-10-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
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2O3X
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![BU of 2o3x by Molmil](/molmil-images/mine/2o3x) | Crystal Structure of the Prokaryotic Ribosomal Decoding Site Complexed with Paromamine Derivative NB30 | 分子名称: | (1R,2R,3S,4R,6S)-4,6-DIAMINO-2-[(5-AMINO-5-DEOXY-BETA-D-RIBOFURANOSYL)OXY]-3-HYDROXYCYCLOHEXYL 2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3') | 著者 | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | 登録日 | 2006-12-02 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites. Chembiochem, 8, 2007
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2O3V
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![BU of 2o3v by Molmil](/molmil-images/mine/2o3v) | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with paromamine derivative NB33 | 分子名称: | (2S,3R,4R,5S,6R)-3-AMINO-4-({[(2S,3R,4R,5S,6R)-3-AMINO-2-{[(1R,2R,3S,4R,6S)-4,6-DIAMINO-2,3-DIHYDROXYCYCLOHEXYL]OXY}-5-HYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-4-YL]OXY}METHOXY)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIOL, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | 著者 | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | 登録日 | 2006-12-02 | 公開日 | 2007-11-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites. Chembiochem, 8, 2007
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1L8N
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![BU of 1l8n by Molmil](/molmil-images/mine/1l8n) | The 1.5A crystal structure of alpha-D-glucuronidase from Bacillus stearothermophilus T-1, complexed with 4-O-methyl-glucuronic acid and xylotriose | 分子名称: | 4-O-methyl-beta-D-glucopyranuronic acid, ALPHA-D-GLUCURONIDASE, GLYCEROL, ... | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | 登録日 | 2002-03-21 | 公開日 | 2003-03-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
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2O3W
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![BU of 2o3w by Molmil](/molmil-images/mine/2o3w) | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site in presence of paromomycin | 分子名称: | PAROMOMYCIN, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | 著者 | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | 登録日 | 2006-12-02 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites. Chembiochem, 8, 2007
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1K9F
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![BU of 1k9f by Molmil](/molmil-images/mine/1k9f) | Crystal structure of a mutated family-67 alpha-D-glucuronidase (E285N) from Bacillus stearothermophilus T-6, complexed with aldotetraouronic acid | 分子名称: | 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, GLYCEROL, alpha-D-glucuronidase | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | 登録日 | 2001-10-29 | 公開日 | 2002-10-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
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2O3Y
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![BU of 2o3y by Molmil](/molmil-images/mine/2o3y) | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site in Presence of Paromamine Derivative NB30 | 分子名称: | RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3'), SPERMINE | 著者 | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | 登録日 | 2006-12-02 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites. Chembiochem, 8, 2007
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1K9E
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![BU of 1k9e by Molmil](/molmil-images/mine/1k9e) | Crystal structure of a mutated family-67 alpha-D-glucuronidase (E285N) from Bacillus stearothermophilus T-6, complexed with 4-O-methyl-glucuronic acid | 分子名称: | 4-O-methyl-alpha-D-glucopyranuronic acid, GLYCEROL, alpha-D-glucuronidase | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | 登録日 | 2001-10-29 | 公開日 | 2002-10-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
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1PHW
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![BU of 1phw by Molmil](/molmil-images/mine/1phw) | Crystal structure of KDO8P synthase in its binary complex with substrate analog 1-deoxy-A5P | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, ANY 5'-MONOPHOSPHATE NUCLEOTIDE | 著者 | Vainer, R, Belakhov, V, Rabkin, E, Baasov, T, Adir, N. | 登録日 | 2003-05-29 | 公開日 | 2004-07-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Crystal structures of Escherichia coli KDO8P synthase complexes reveal the source of catalytic irreversibility. J.Mol.Biol., 351, 2005
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1PHQ
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![BU of 1phq by Molmil](/molmil-images/mine/1phq) | Crystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEP | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, 3-FLUORO-2-(PHOSPHONOOXY)PROPANOIC ACID | 著者 | Vainer, R, Adir, N, Baasov, T, Belakhov, V, Rabkin, E. | 登録日 | 2003-05-29 | 公開日 | 2004-07-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystallographic Analysis of the Phosphoenol Pyruvate Binding Site in E. Coli KDO8P Synthase To be Published
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1PL9
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![BU of 1pl9 by Molmil](/molmil-images/mine/1pl9) | Crystal structure of KDO8P synthase in its binary complex with substrate analog Z-FPEP | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, 3-FLUORO-2-(PHOSPHONOOXY)PROPANOIC ACID | 著者 | Vainer, R, Adir, N, Baasov, T, Belakhov, V, Rabkin, E. | 登録日 | 2003-06-08 | 公開日 | 2004-07-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of KDO8P synthase in its binary complex with substrate analog Z-FPEP To be Published
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1PZ3
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![BU of 1pz3 by Molmil](/molmil-images/mine/1pz3) | Crystal structure of a family 51 (GH51) alpha-L-arabinofuranosidase from Geobacillus stearothermophilus T6 | 分子名称: | Alpha-L-arabinofuranosidase, GLYCEROL | 著者 | Hoevel, K, Shallom, D, Niefind, K, Belakhov, V, Shoham, G, Baasov, T, Shoham, Y, Schomburg, D. | 登録日 | 2003-07-09 | 公開日 | 2003-10-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure and snapshots along the reaction pathway of a family 51 alpha-L-arabinofuranosidase Embo J., 22, 2003
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1Q3N
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![BU of 1q3n by Molmil](/molmil-images/mine/1q3n) | Crystal structure of KDO8P synthase in its binary complex with substrate PEP | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHOENOLPYRUVATE | 著者 | Vainer, R, Belakhov, V, Rabkin, E, Baasov, T, Adir, N. | 登録日 | 2003-07-31 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of Escherichia coli KDO8P synthase complexes reveal the source of catalytic irreversibility. J.Mol.Biol., 351, 2005
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1PZ2
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![BU of 1pz2 by Molmil](/molmil-images/mine/1pz2) | Crystal structure of a transient covalent reaction intermediate of a family 51 alpha-L-arabinofuranosidase | 分子名称: | Alpha-L-arabinofuranosidase, alpha-L-arabinofuranose | 著者 | Hoevel, K, Shallom, D, Niefind, K, Belakhov, V, Shoham, G, Baasov, T, Shoham, Y, Schomburg, D. | 登録日 | 2003-07-09 | 公開日 | 2003-10-07 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure and snapshots along the reaction pathway of a family 51 alpha-L-arabinofuranosidase Embo J., 22, 2003
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