1CLP
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![BU of 1clp by Molmil](/molmil-images/mine/1clp) | CRYSTAL STRUCTURE OF A CALCIUM-INDEPENDENT PHOSPHOLIPASELIKE MYOTOXIC PROTEIN FROM BOTHROPS ASPER VENOM | Descriptor: | MYOTOXIN II | Authors: | Arni, R.K, Ward, R.J, Gutierrez, J.M, Tulinsky, A. | Deposit date: | 1994-09-12 | Release date: | 1994-11-30 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom. Acta Crystallogr.,Sect.D, 51, 1995
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1GOD
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![BU of 1god by Molmil](/molmil-images/mine/1god) | MONOMERIC LYS-49 PHOSPHOLIPASE A2 HOMOLOGUE ISOLATED FROM THE VENOM OF CERROPHIDION (BOTHROPS) GODMANI | Descriptor: | PROTEIN (PHOSPHOLIPASE A2) | Authors: | Arni, R.K, Fontes, M.R.M, Barberato, C, Gutierrez, J.M, Diaz-Oreiro, C, Ward, R.J. | Deposit date: | 1999-04-16 | Release date: | 1999-04-23 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of myotoxin II, a monomeric Lys49-phospholipase A2 homologue isolated from the venom of Cerrophidion (Bothrops) godmani. Arch.Biochem.Biophys., 366, 1999
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1B2M
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![BU of 1b2m by Molmil](/molmil-images/mine/1b2m) | THREE-DIMENSIONAL STRUCTURE OF RIBONULCEASE T1 COMPLEXED WITH AN ISOSTERIC PHOSPHONATE ANALOGUE OF GPU: ALTERNATE SUBSTRATE BINDING MODES AND CATALYSIS. | Descriptor: | 5'-R(*GP*(U34))-3', RIBONUCLEASE T1 | Authors: | Arni, R.K, Watanabe, L, Ward, R.J, Kreitman, R.J, Kumar, K, Walz Jr, F.G. | Deposit date: | 1998-11-27 | Release date: | 1999-03-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis. Biochemistry, 38, 1999
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1RN1
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![BU of 1rn1 by Molmil](/molmil-images/mine/1rn1) | THREE-DIMENSIONAL STRUCTURE OF GLN 25-RIBONUCLEASE T1 AT 1.84 ANGSTROMS RESOLUTION: STRUCTURAL VARIATIONS AT THE BASE RECOGNITION AND CATALYTIC SITES | Descriptor: | RIBONUCLEASE T1 ISOZYME, SULFATE ION | Authors: | Arni, R.K, Pal, G.P, Ravichandran, K.G, Tulinsky, A, Walz Junior, F.G, Metcalf, P. | Deposit date: | 1991-11-22 | Release date: | 1994-01-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Three-dimensional structure of Gln25-ribonuclease T1 at 1.84-A resolution: structural variations at the base recognition and catalytic sites. Biochemistry, 31, 1992
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5DOM
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![BU of 5dom by Molmil](/molmil-images/mine/5dom) | Crystal structure, maturation and flocculating properties of a 2S albumin from Moringa oleifera seeds | Descriptor: | 1,2-ETHANEDIOL, 2S albumin, ACETATE ION | Authors: | Ullah, A, Murakami, M.T, Arni, R.K. | Deposit date: | 2015-09-11 | Release date: | 2015-11-11 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structure of mature 2S albumin from Moringa oleifera seeds. Biochem.Biophys.Res.Commun., 468, 2015
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3KVE
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![BU of 3kve by Molmil](/molmil-images/mine/3kve) | Structure of native L-amino acid oxidase from Vipera ammodytes ammodytes: stabilization of the quaternary structure by divalent ions and structural changes in the dynamic active site | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase, ... | Authors: | Gergiova, D, Murakami, M.T, Perbandt, M, Arni, R.K, Betzel, C. | Deposit date: | 2009-11-30 | Release date: | 2010-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structure of native L-amino acid oxidase from Vipera ammodytes ammodytes: stabilization of the quaternary structure by divalent ions and structural changes in the dynamic active site To be Published
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8DAX
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![BU of 8dax by Molmil](/molmil-images/mine/8dax) | New insights into the P186 flip and oligomeric state of Staphylococcus aureus exfoliative toxin E: implications for the exfoliative mechanism | Descriptor: | Exfoliative toxin E | Authors: | Gismene, C, Nascimento, A.F.Z, Hernandez-Gonzalez, J.E, Santisteban, A.R.N, de Moraes, F.R, Arni, R.K, Mariutti, R.B. | Deposit date: | 2022-06-14 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Staphylococcus aureus Exfoliative Toxin E, Oligomeric State and Flip of P186: Implications for Its Action Mechanism. Int J Mol Sci, 23, 2022
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8T3J
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![BU of 8t3j by Molmil](/molmil-images/mine/8t3j) | Crystal structure of native exfoliative toxin C (ExhC) from Mammaliicoccus sciuri | Descriptor: | Exfoliative toxin C | Authors: | Calil, F.A, Gismene, C, Hernandez Gonzalez, J.E, Ziem Nascimento, A.F, Santisteban, A.R.N, Arni, R.K, Barros Mariutti, R. | Deposit date: | 2023-06-07 | Release date: | 2023-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | Necrotic activity of ExhC from Mammaliicoccus sciuri is mediated by specific amino acid residues. Int.J.Biol.Macromol., 254, 2024
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8T3I
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![BU of 8t3i by Molmil](/molmil-images/mine/8t3i) | Crystal structure of mutant exfoliative toxin C (ExhC) from Mammaliicoccus sciuri | Descriptor: | Exfoliative toxin C | Authors: | Gismene, C, Calil, F.A, Hernandez Gonzalez, J.E, Ziem Nascimento, A.F, Santisteban, A.R.N, Arni, R.K, Barros Mariutti, R. | Deposit date: | 2023-06-07 | Release date: | 2023-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Necrotic activity of ExhC from Mammaliicoccus sciuri is mediated by specific amino acid residues. Int.J.Biol.Macromol., 254, 2024
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5JVO
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![BU of 5jvo by Molmil](/molmil-images/mine/5jvo) | Crystal structure of the Arginine Repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis | Descriptor: | Arginine repressor, SULFATE ION, TYROSINE | Authors: | Mariutti, R.B, Ullah, A, Murakami, M.T, Arni, R.K. | Deposit date: | 2016-05-11 | Release date: | 2016-08-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tyrosine binding and promiscuity in the arginine repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis. Biochem.Biophys.Res.Commun., 475, 2016
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3UX7
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![BU of 3ux7 by Molmil](/molmil-images/mine/3ux7) | Crystal structure of a dimeric myotoxic component of the Vipera ammodytes meridionalis venom reveals determinants of myotoxicity and membrane damaging activity | Descriptor: | Ammodytin L(1) isoform, SULFATE ION | Authors: | Georgieva, D, Coronado, M, Oberthuer, D, Buck, F, Duhalov, D, Arni, R.K, Genov, N, Betzel, C. | Deposit date: | 2011-12-04 | Release date: | 2012-04-25 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Crystal structure of a dimeric Ser49 PLA(2)-like myotoxic component of the Vipera ammodytes meridionalis venomics reveals determinants of myotoxicity and membrane damaging activity. Mol Biosyst, 8, 2012
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5O6F
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![BU of 5o6f by Molmil](/molmil-images/mine/5o6f) | NMR structure of cold shock protein A from Corynebacterium pseudotuberculosis | Descriptor: | Cold-shock protein | Authors: | Caruso, I.P, Panwalkar, V, Coronado, M.A, Dingley, A.J, Cornelio, M.L, Willbold, D, Arni, R.K, Eberle, R.J. | Deposit date: | 2017-06-06 | Release date: | 2017-07-19 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure and interaction of Corynebacterium pseudotuberculosis cold shock protein A with Y-box single-stranded DNA fragment. FEBS J., 285, 2018
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6WJP
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![BU of 6wjp by Molmil](/molmil-images/mine/6wjp) | Crystal structure of Arginine Repressor P115Q mutant from the pathogenic bacterium Corynebacterium pseudotuberculosis bound to arginine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ARGININE, ... | Authors: | Nascimento, A.F.Z, Hernandez-Gonzalez, J.E, de Morais, M.A.B, Murakami, M.T, Carareto, C.M.A, Arni, R.K, Mariutti, R.B. | Deposit date: | 2020-04-14 | Release date: | 2020-04-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | A single P115Q mutation modulates specificity in the Corynebacterium pseudotuberculosis arginine repressor. Biochim Biophys Acta Gen Subj, 1864, 2020
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4GSO
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![BU of 4gso by Molmil](/molmil-images/mine/4gso) | structure of Jararacussin-I | Descriptor: | Thrombin-like enzyme BjussuSP-1 | Authors: | Ullah, A, Souza, T.C.A.B, Zanphorlin, L.M, Mariutti, R, Sanata, S.V, Murakami, M.T, Arni, R.K. | Deposit date: | 2012-08-28 | Release date: | 2012-12-12 | Last modified: | 2013-01-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of Jararacussin-I: The highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes. Protein Sci., 22, 2013
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6WJO
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![BU of 6wjo by Molmil](/molmil-images/mine/6wjo) | Crystal structure of wild-type Arginine Repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis bound to tyrosine | Descriptor: | Arginine repressor, SODIUM ION, SULFATE ION, ... | Authors: | Nascimento, A.F.Z, Hernandez-Gonzalez, J.E, de Morais, M.A.B, Murakami, M.T, Carareto, C.M.A, Arni, R.K, Mariutti, R.B. | Deposit date: | 2020-04-14 | Release date: | 2020-04-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.693 Å) | Cite: | A single P115Q mutation modulates specificity in the Corynebacterium pseudotuberculosis arginine repressor. Biochim Biophys Acta Gen Subj, 1864, 2020
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4RW3
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![BU of 4rw3 by Molmil](/molmil-images/mine/4rw3) | Structural insights into substrate binding of brown spider venom class II phospholipases D | Descriptor: | D-MYO-INOSITOL-1-PHOSPHATE, DECANOIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Coronado, M.A, Ullah, A, da Silva, L.S, Chaves-Moreira, D, Vuitika, L, Chaim, O.M, Veiga, S.S, Chahine, J, Murakami, M.T, Arni, R.K. | Deposit date: | 2014-12-01 | Release date: | 2015-06-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. Curr Protein Pept Sci, 16, 2015
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4GV5
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![BU of 4gv5 by Molmil](/molmil-images/mine/4gv5) | X-ray structure of crotamine, a cell-penetrating peptide from the Brazilian snake Crotalus durissus terrificus | Descriptor: | Crotamine Ile-19, GLYCEROL, SULFATE ION, ... | Authors: | Coronado, M.A, Gabdulkhakov, A, Georgieva, D, Sankaran, B, Murakami, M.T, Arni, R.K, Betzel, C. | Deposit date: | 2012-08-30 | Release date: | 2013-09-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the polypeptide crotamine from the Brazilian rattlesnake Crotalus durissus terrificus. Acta Crystallogr.,Sect.D, 69, 2013
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4RW5
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![BU of 4rw5 by Molmil](/molmil-images/mine/4rw5) | Structural insights into substrate binding of brown spider venom class II phospholipases D | Descriptor: | GLYCEROL, MAGNESIUM ION, N-TRIDECANOIC ACID, ... | Authors: | Coronado, M.A, Ullah, A, da Silva, L.S, Chaves-Moreira, D, Vuitika, L, Chaim, O.M, Veiga, S.S, Chahine, J, Murakami, M.T, Arni, R.K. | Deposit date: | 2014-12-01 | Release date: | 2015-06-03 | Last modified: | 2015-12-16 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. Curr Protein Pept Sci, 16, 2015
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2PH4
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![BU of 2ph4 by Molmil](/molmil-images/mine/2ph4) | Crystal structure of a novel Arg49 phospholipase A2 homologue from Zhaoermia mangshanensis venom | Descriptor: | DI(HYDROXYETHYL)ETHER, SULFATE ION, Zhaoermiatoxin | Authors: | Murakami, M.T, Kuch, U, Mebs, D, Arni, R.K. | Deposit date: | 2007-04-10 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of a novel myotoxic Arg49 phospholipase A(2) homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus. Toxicon, 51, 2008
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5C2Z
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![BU of 5c2z by Molmil](/molmil-images/mine/5c2z) | Molecular insights into the specificity of exfoliative toxins from Staphylococcus aureus | Descriptor: | Exfoliative toxin D2 | Authors: | Mariutti, R.B, Souza, T.A.C.B, Ullah, A, Zanphorlin, L.M, Murakami, M.T, Arni, R.K. | Deposit date: | 2015-06-16 | Release date: | 2016-04-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9553 Å) | Cite: | Crystal structure of Staphylococcus aureus exfoliative toxin D-like protein: Structural basis for the high specificity of exfoliative toxins. Biochem.Biophys.Res.Commun., 467, 2015
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3RLG
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![BU of 3rlg by Molmil](/molmil-images/mine/3rlg) | Crystal structure of Loxosceles intermedia phospholipase D isoform 1 H12A mutant | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Giuseppe, P.O, Ullah, A, Veiga, S.S, Murakami, M.T, Arni, R.K. | Deposit date: | 2011-04-19 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallization and preliminary X-ray diffraction analysis of a class II phospholipase D from Loxosceles intermedia venom. Acta Crystallogr.,Sect.F, 67, 2011
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2AIP
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![BU of 2aip by Molmil](/molmil-images/mine/2aip) | |
1XXS
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![BU of 1xxs by Molmil](/molmil-images/mine/1xxs) | Structural insights for fatty acid binding in a Lys49 phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid | Descriptor: | Phospholipase A2 homolog 2, STEARIC ACID, SULFATE ION | Authors: | Watanabe, L, Soares, A.M, Ward, R.J, Fontes, M.R, Arni, R.K. | Deposit date: | 2004-11-08 | Release date: | 2005-03-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights for fatty acid binding in a Lys49-phospholipase A(2): crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid Biochimie, 87, 2005
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2F9R
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![BU of 2f9r by Molmil](/molmil-images/mine/2f9r) | Crystal structure of the inactive state of the Smase I, a sphingomyelinase D from Loxosceles laeta venom | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Sphingomyelinase D 1 | Authors: | Murakami, M.T, Gabdoulkhakov, A, Fernandes-Pedrosa, M.F, Betzel, C, Tambourgi, D.V, Arni, R.K. | Deposit date: | 2005-12-06 | Release date: | 2006-06-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D. J.Biol.Chem., 280, 2005
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3RLH
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![BU of 3rlh by Molmil](/molmil-images/mine/3rlh) | Crystal structure of a class II phospholipase D from Loxosceles intermedia venom | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Giuseppe, P.O, Ullah, A, Veiga, S.S, Murakami, M.T, Arni, R.K. | Deposit date: | 2011-04-19 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structure of a novel class II phospholipase D: Catalytic cleft is modified by a disulphide bridge. Biochem.Biophys.Res.Commun., 409, 2011
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