2F9R
Crystal structure of the inactive state of the Smase I, a sphingomyelinase D from Loxosceles laeta venom
Summary for 2F9R
Entry DOI | 10.2210/pdb2f9r/pdb |
Related | 1XX1 |
Descriptor | Sphingomyelinase D 1, MAGNESIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | sphingomyelinase d, catalytic activity, magnesium-binding site, inactive state, hydrolase |
Biological source | Loxosceles laeta |
Cellular location | Secreted: Q8I914 |
Total number of polymer chains | 4 |
Total formula weight | 129143.95 |
Authors | Murakami, M.T.,Gabdoulkhakov, A.,Fernandes-Pedrosa, M.F.,Betzel, C.,Tambourgi, D.V.,Arni, R.K. (deposition date: 2005-12-06, release date: 2006-06-27, Last modification date: 2023-08-30) |
Primary citation | Murakami, M.T.,Gabdoulkhakov, A.,Fernandes-Pedrosa, M.F.,Tambourgi, D.V.,Arni, R.K. Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D. J.Biol.Chem., 280:13658-13664, 2005 Cited by PubMed: 15654080DOI: 10.1074/jbc.M412437200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report