7WOX
| PPARgamma antagonist (MMT-160)- PPARgamma LBD complex | Descriptor: | N-[[5-(3-phenylprop-2-ynoylamino)-2-propoxy-phenyl]methyl]-4-pyrimidin-2-yl-benzamide, Peroxisome proliferator-activated receptor gamma | Authors: | Yoshizawa, M, Aoyama, T, Itoh, T, Miyachi, H. | Deposit date: | 2022-01-22 | Release date: | 2022-04-13 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Arylalkynyl amide-type peroxisome proliferator-activated receptor gamma (PPAR gamma )-selective antagonists covalently bind to the PPAR gamma ligand binding domain with a unique binding mode. Bioorg.Med.Chem.Lett., 64, 2022
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