2I6R
 
 | | Crystal structure of E. coli HypE, a hydrogenase maturation protein | | 分子名称: | HypE protein | | 著者 | Rangarajan, E.S, Proteau, A, Iannuzzi, P, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2006-08-29 | | 公開日 | 2007-10-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of [NiFe] hydrogenase maturation protein HypE from Escherichia coli and its interaction with HypF.
J.Bacteriol., 190, 2008
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2W3I
 | | Crystal Structure of FXa in complex with 4,4-disubstituted pyrrolidine-1,2-dicarboxamide inhibitor 2 | | 分子名称: | (2R,4S)-N^1^-(4-chlorophenyl)-4-(2,4-difluorophenyl)-4-hydroxy-N^2^-(2-oxo-2H-1,3'-bipyridin-6'-yl)pyrrolidine-1,2-dicarboxamide, CALCIUM ION, COAGULATION FACTOR X, ... | | 著者 | Zhang, E, Mochalkin, I, Casimiro-Garcia, A, Van Huis, C.A. | | 登録日 | 2008-11-12 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Exploration of 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamides as Potent, Orally Active Factor Xa Inhibitors with Extended Duration of Action.
Bioorg.Med.Chem., 17, 2009
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7UUW
 | | Cryogenic electron microscopy 3D map of F-actin bound by the Actin Binding Domain of alpha-catenin ortholog, HMP1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Rangarajan, E.S, Smith, E.W, Izard, T. | | 登録日 | 2022-04-29 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | The nematode alpha-catenin ortholog, HMP1, has an extended alpha-helix when bound to actin filaments.
J.Biol.Chem., 299, 2022
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7UXF
 | | Cryogenic electron microscopy 3D map of F-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Rangarajan, E.S, Smith, E.W, Izard, T. | | 登録日 | 2022-05-05 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Distinct inter-domain interactions of dimeric versus monomeric alpha-catenin link cell junctions to filaments.
Commun Biol, 6, 2023
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7UTJ
 | | Cryogenic electron microscopy 3D map of F-actin bound by human dimeric alpha-catenin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Rangarajan, E.S, Smith, E.W, Izard, T. | | 登録日 | 2022-04-27 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Distinct inter-domain interactions of dimeric versus monomeric alpha-catenin link cell junctions to filaments.
Commun Biol, 6, 2023
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4W4Q
 | | Glucose isomerase structure determined by serial femtosecond crystallography at SACLA | | 分子名称: | CALCIUM ION, Xylose isomerase | | 著者 | Nango, E, Tanaka, T, Sugahara, M, Suzuki, M, Iwata, S. | | 登録日 | 2014-08-15 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Grease matrix as a versatile carrier of proteins for serial crystallography
Nat.Methods, 12, 2015
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5VED
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8BWK
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5VEF
 | | PAK4 kinase domain in complex with fasudil | | 分子名称: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, ACETATE ION, Serine/threonine-protein kinase PAK 4 | | 著者 | Zhang, E.Y, Ha, B.H, Boggon, T.J. | | 登録日 | 2017-04-04 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | | 主引用文献 | PAK4 crystal structures suggest unusual kinase conformational movements.
Biochim. Biophys. Acta, 1866, 2018
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5VEE
 | | PAK4 kinase domain in complex with FRAX486 | | 分子名称: | 6-(2,4-dichlorophenyl)-8-ethyl-2-{[3-fluoro-4-(piperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Serine/threonine-protein kinase PAK 4 | | 著者 | Zhang, E.Y, Ha, B.H, Boggon, T.J. | | 登録日 | 2017-04-04 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | PAK4 crystal structures suggest unusual kinase conformational movements.
Biochim. Biophys. Acta, 1866, 2018
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4YWU
 | | Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes | | 分子名称: | 4-oxobutanoic acid, SULFATE ION, Succinic semialdehyde dehydrogenase | | 著者 | Jang, E.H, Park, S.A, Chi, Y.M, Lee, K.S. | | 登録日 | 2015-03-21 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes.
Biochem.Biophys.Res.Commun., 461, 2015
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2IUC
 | | Structure of alkaline phosphatase from the Antarctic bacterium TAB5 | | 分子名称: | ALKALINE PHOSPHATASE, CACODYLATE ION, MAGNESIUM ION, ... | | 著者 | Wang, E, Koutsioulis, D, Leiros, H.K.S, Andersen, O.A, Bouriotis, V, Hough, E, Heikinheimo, P. | | 登録日 | 2006-06-01 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
J.Mol.Biol., 366, 2007
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3HBN
 | | Crystal structure PseG-UDP complex from Campylobacter jejuni | | 分子名称: | CHLORIDE ION, GLYCEROL, UDP-sugar hydrolase, ... | | 著者 | Rangarajan, E.S, Proteau, A, Cygler, M, Matte, A, Sulea, T, Schoenhofen, I.C. | | 登録日 | 2009-05-04 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
J.Biol.Chem., 284, 2009
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5XGA
 | | Crystal structure of the EnvZ periplasmic domain with CHAPS | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETIC ACID, Osmolarity sensor protein EnvZ | | 著者 | Hwang, E, Cheong, H.K, Jeon, Y.H, Cheong, C. | | 登録日 | 2017-04-13 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | Crystal structure of the EnvZ periplasmic domain with CHAPS.
FEBS Lett., 591, 2017
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3LGE
 | | Crystal structure of rabbit muscle aldolase-SNX9 LC4 complex | | 分子名称: | Fructose-bisphosphate aldolase A, Sorting nexin-9 | | 著者 | Rangarajan, E.S, Park, H, Fortin, E, Sygusch, J, Izard, T. | | 登録日 | 2010-01-20 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mechanism of aldolase control of sorting nexin 9 function in endocytosis.
J.Biol.Chem., 285, 2010
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5GM0
 | | Tl-gal with lactose | | 分子名称: | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, galectin | | 著者 | Hwang, E.Y. | | 登録日 | 2016-07-12 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Basis for Carbohydrate Recognition and Anti-inflammatory Modulation by Gastrointestinal Nematode Parasite Toxascaris leonina Galectin
J. Biol. Chem., 291, 2016
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6JZI
 | | Structure of hen egg-white lysozyme obtained from SFX experiments under atmospheric pressure | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Nango, E, Sugahara, M, Nakane, T, Tanaka, T, Iwata, S. | | 登録日 | 2019-05-02 | | 公開日 | 2019-10-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure.
J.Appl.Crystallogr., 52, 2019
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5B6V
 | | A three dimensional movie of structural changes in bacteriorhodopsin: resting state structure | | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | | 著者 | Nango, E, Royant, A, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S. | | 登録日 | 2016-06-02 | | 公開日 | 2016-12-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
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3HBM
 | | Crystal Structure of PseG from Campylobacter jejuni | | 分子名称: | SULFATE ION, UDP-sugar hydrolase | | 著者 | Rangarajan, E.S, Proteau, A, Cygler, M, Matte, A, Sulea, T, Schoenhofen, I.C. | | 登録日 | 2009-05-04 | | 公開日 | 2009-05-26 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
J.Biol.Chem., 284, 2009
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6JZH
 | | Structure of human A2A adenosine receptor in complex with ZM241385 obtained from SFX experiments under atmospheric pressure | | 分子名称: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, CHOLESTEROL, ... | | 著者 | Nango, E, Shimamura, T, Nakane, T, Yamanaka, Y, Mori, C, Kimura, K.T, Fujiwara, T, Tanaka, T, Iwata, S. | | 登録日 | 2019-05-02 | | 公開日 | 2019-10-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure.
J.Appl.Crystallogr., 52, 2019
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4OH8
 | | Crystal Structure of the human MST1-RASSF5 SARAH heterodimer | | 分子名称: | Ras association domain-containing protein 5, Serine/threonine-protein kinase 4 | | 著者 | Hwang, E, Cheong, H.-K, Ul Mushtaq, A, Kim, H.-Y, Yeo, K.J, Kim, E, Lee, W.C, Hwang, K.Y, Cheong, C, Jeon, Y.H. | | 登録日 | 2014-01-17 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.281 Å) | | 主引用文献 | Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway.
Acta Crystallogr.,Sect.D, 70, 2014
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2JO8
 | | Solution structure of C-terminal domain of human mammalian sterile 20-like kinase 1 (MST1) | | 分子名称: | Serine/threonine-protein kinase 4 | | 著者 | Hwang, E, Ryu, K.-S, Paakkonen, K, Guntert, P, Cheong, H.-K, Lim, D.-S, Lee, J.O, Jeon, Y.H, Cheong, C. | | 登録日 | 2007-02-26 | | 公開日 | 2007-05-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2PHB
 | | An Orally Efficacious Factor Xa Inhibitor | | 分子名称: | (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE, CALCIUM ION, Coagulation factor X, ... | | 著者 | Zhang, E, Kohrt, J.T, Bigge, C.F, Finzel, B.C. | | 登録日 | 2007-04-10 | | 公開日 | 2008-03-25 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitor
Chem.Biol.Drug Des., 70, 2007
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2VT2
 | | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | | 著者 | Wang, E, Bauer, M.C, Rogstam, A, Linse, S, Logan, D.T, von Wachenfeldt, C. | | 登録日 | 2008-05-08 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
Mol. Microbiol., 69, 2008
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2VT3
 | | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | | 著者 | Wang, E, Bauer, M.C, Rogstam, A, Linse, S, Logan, D, von Wachenfeldt, C. | | 登録日 | 2008-05-08 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
Mol. Microbiol., 69, 2008
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