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PDB: 1 results

3Q61
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3'-Fluoro Hexitol Nucleic Acid DNA Structure
Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(F3H)P*AP*CP*GP*C)-3')
Authors:Seth, P.R, Allerson, C.R, Prakash, T.P, Siwkowski, A, Berdeja, A, Yu, J, Pallan, P.S, Watt, A.T, Gaus, H, Bhat, B, Egli, M, Swayze, E.E.
Deposit date:2010-12-30
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides.
J.Am.Chem.Soc., 133, 2011

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