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PDB: 3 results

3OZ5
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BU of 3oz5 by Molmil
S-Methyl Carbocyclic LNA
Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(UMX)P*AP*CP*GP*C)-3'), SPERMINE
Authors:Seth, P.R, Allerson, C.A, Berdeja, A, Siwkowski, A, Pallan, P.S, Gaus, H, Prakash, T.P, Watt, A.T, Egli, M, Swayze, E.E.
Deposit date:2010-09-24
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA.
J.Am.Chem.Soc., 132, 2010
3OZ3
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BU of 3oz3 by Molmil
Vinyl Carbocyclic LNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*(UVX)P*AP*CP*GP*C)-3')
Authors:Seth, P.R, Allerson, C.A, Berdeja, A, Siwkowski, A, Pallan, P.S, Gaus, H, Prakash, T.P, Watt, A.T, Egli, M, Swayze, E.E.
Deposit date:2010-09-24
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA.
J.Am.Chem.Soc., 132, 2010
3OZ4
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BU of 3oz4 by Molmil
R-Methyl Carbocyclic LNA
Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(URX)P*AP*CP*GP*C)-3')
Authors:Seth, P.R, Allerson, C.A, Berdeja, A, Siwkowski, A, Pallan, P.S, Gaus, H, Prakash, T.P, Watt, A.T, Egli, M, Swayze, E.E.
Deposit date:2010-09-24
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA.
J.Am.Chem.Soc., 132, 2010

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