1UJL
 
 | | Solution Structure of the HERG K+ channel S5-P extracellular linker | | Descriptor: | Potassium voltage-gated channel subfamily H member 2 | | Authors: | Torres, A.M, Bansal, P.S, Sunde, M, Clarke, C.E, Bursill, J.A, Smith, D.J, Bauskin, A, Breit, S.N, Campbell, T.J, Alewood, P.F, Kuchel, P.W, Vandenberg, J.I. | | Deposit date: | 2003-08-05 | | Release date: | 2003-11-04 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix
in C-type inactivation.
J.Biol.Chem., 278, 2003
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2EW4
 | | Solution structure of MrIA | | Descriptor: | MrIA | | Authors: | Nilsson, K.P, Lovelace, E.S, Caesar, C.E, Tynngard, N, Alewood, P.F, Johansson, H.M, Sharpe, I.A, Lewis, R.J, Daly, N.L, Craik, D.J. | | Deposit date: | 2005-11-02 | | Release date: | 2005-11-15 | | Last modified: | 2020-06-24 | | Method: | SOLUTION NMR | | Cite: | Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter
Biopolymers, 80, 2005
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2J15
 | | Cyclic MrIA: An exceptionally stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. | | Descriptor: | MAI126P | | Authors: | Lovelace, E.S, Armishaw, C.J, Colgrave, M.L, Walstrom, M.E, Alewood, P.F, Daly, N.L, Craik, D.J. | | Deposit date: | 2006-08-09 | | Release date: | 2006-11-01 | | Last modified: | 2018-05-09 | | Method: | SOLUTION NMR | | Cite: | Cyclic MrIA: a stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter.
J. Med. Chem., 49, 2006
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2JM2
 | | Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs | | Descriptor: | Insulin-like growth factor-binding protein 6 | | Authors: | Chandrashekaran, I.R, Yao, S, Wang, C.C, Bansal, P.S, Alewood, P.F, Forbes, B.E, Wallace, J.C, Bach, L.A, Norton, R.S. | | Deposit date: | 2006-09-18 | | Release date: | 2007-03-27 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | The N-Terminal Subdomain of Insulin-like Growth Factor (IGF) Binding Protein 6. Structure and Interaction with IGFs
Biochemistry, 46, 2007
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1IEN
 | | SOLUTION STRUCTURE OF TIA | | Descriptor: | PROTEIN TIA | | Authors: | Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J. | | Deposit date: | 2001-04-10 | | Release date: | 2002-04-03 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
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1IEO
 | | SOLUTION STRUCTURE OF MRIB-NH2 | | Descriptor: | PROTEIN MRIB-NH2 | | Authors: | Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J. | | Deposit date: | 2001-04-10 | | Release date: | 2002-04-03 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
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1KQH
 | | NMR Solution Structure of the cis Pro30 Isomer of ACTX-Hi:OB4219 | | Descriptor: | ACTX-Hi:OB4219 | | Authors: | Rosengren, K.J, Wilson, D, Daly, N.L, Alewood, P.F, Craik, D.J. | | Deposit date: | 2002-01-05 | | Release date: | 2002-02-06 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin
from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within
its four disulfide bonds
Biochemistry, 41, 2002
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1KQI
 | | NMR Solution Structure of the trans Pro30 Isomer of ACTX-Hi:OB4219 | | Descriptor: | ACTX-Hi:OB4219 | | Authors: | Rosengren, K.J, Wilson, D, Daly, N.L, Alewood, P.F, Craik, D.J. | | Deposit date: | 2002-01-06 | | Release date: | 2002-02-06 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin
from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within
its four disulfide bonds
Biochemistry, 41, 2002
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1GIB
 | | MU-CONOTOXIN GIIIB, NMR | | Descriptor: | MU-CONOTOXIN GIIIB | | Authors: | Hill, J.M, Alewood, P.F, Craik, D.J. | | Deposit date: | 1996-04-17 | | Release date: | 1996-11-08 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels.
Biochemistry, 35, 1996
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1XGB
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1XGC
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1XGA
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1ZUE
 | | Revised Solution Structure of DLP-2 | | Descriptor: | Defensin-like peptide 2/4 | | Authors: | Torres, A.M, Tsampazi, C, Geraghty, D.P, Bansal, P.S, Alewood, P.F, Kuchel, P.W. | | Deposit date: | 2005-05-30 | | Release date: | 2005-08-02 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties.
Biochem.J., 391, 2005
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1ZUF
 | | Solution Structure of DLP-4 | | Descriptor: | Defensin-like peptide 2/4 | | Authors: | Torres, A.M, Tsampazi, C, Geraghty, D.P, Bansal, P.S, Alewood, P.F, Kuchel, P.W. | | Deposit date: | 2005-05-31 | | Release date: | 2005-08-02 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties.
Biochem.J., 391, 2005
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2NS3
 | | Solution structure of ribbon BuIA | | Descriptor: | Alpha-conotoxin BuIA | | Authors: | Jin, A.H, Brandstaetter, H, Nevin, S.T, Tan, C.C, Clark, R.J, Adams, D.J, Alewood, P.F, Craik, D.J, Daly, N.L. | | Deposit date: | 2006-11-03 | | Release date: | 2007-09-25 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics
Bmc Struct.Biol., 7, 2007
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2MFA
 | | Mambalgin-2 | | Descriptor: | Mambalgin-2 | | Authors: | Schroeder, C.I, Rash, L.D, Vila-Farres, X, Rosengren, K.J, Mobli, M, King, G.F, Alewood, P.F, Craik, D.J, Durek, T. | | Deposit date: | 2013-10-08 | | Release date: | 2014-01-01 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.
Angew.Chem.Int.Ed.Engl., 53, 2014
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2KYJ
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1MXP
 | | Solution structure of the ribbon disulfide bond isomer of alpha-conotoxin AuIB | | Descriptor: | alpha-conotoxin AuIB | | Authors: | Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J. | | Deposit date: | 2002-10-03 | | Release date: | 2002-12-30 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
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1PEN
 | | ALPHA-CONOTOXIN PNI1 | | Descriptor: | ALPHA-CONOTOXIN PNIA | | Authors: | Hu, S.-H, Gehrmann, J, Guddat, L.W, Alewood, P.F, Craik, D.J, Martin, J.L. | | Deposit date: | 1996-01-29 | | Release date: | 1997-04-21 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus.
Structure, 4, 1996
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1MII
 | | SOLUTION STRUCTURE OF ALPHA-CONOTOXIN MII | | Descriptor: | PROTEIN (ALPHA CONOTOXIN MII) | | Authors: | Hill, J.M, Oomen, C.J, Miranda, L.P, Bingham, J.P, Alewood, P.F, Craik, D.J. | | Deposit date: | 1998-10-05 | | Release date: | 1998-10-21 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity.
Biochemistry, 37, 1998
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1MXN
 | | Solution structure of alpha-conotoxin AuIB | | Descriptor: | alpha-conotoxin AuIB | | Authors: | Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J. | | Deposit date: | 2002-10-02 | | Release date: | 2002-12-30 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
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1MTQ
 | | THREE-DIMENSIONAL SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID BY NMR SPECTROSCOPY | | Descriptor: | alpha-conotoxin GID | | Authors: | Nicke, A, Loughnan, M.L, Millard, E.L, Alewood, P.F, Adams, D.J, Daly, N.L, Craik, D.J, Lewis, R.J. | | Deposit date: | 2002-09-22 | | Release date: | 2003-02-11 | | Last modified: | 2020-06-24 | | Method: | SOLUTION NMR | | Cite: | Isolation, Structure, and Activity of GID, a Novel alpha 4/7-Conotoxin with an Extended N-terminal Sequence
J.BIOL.CHEM., 278, 2003
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1MVI
 | | N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA, NMR, 15 STRUCTURES | | Descriptor: | MVIIA | | Authors: | Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J. | | Deposit date: | 1996-08-02 | | Release date: | 1997-08-12 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
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1MVJ
 | | N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES | | Descriptor: | SVIB | | Authors: | Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J. | | Deposit date: | 1996-08-02 | | Release date: | 1997-08-12 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
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1A0M
 | | 1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI | | Descriptor: | ALPHA-CONOTOXIN [TYR15]-EPI | | Authors: | Hu, S.-H, Loughnan, M, Miller, R, Weeks, C.M, Blessing, R.H, Alewood, P.F, Lewis, R.J, Martin, J.L. | | Deposit date: | 1997-12-03 | | Release date: | 1999-01-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods.
Biochemistry, 37, 1998
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