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PDB: 105 件

3BSH
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Barley alpha-amylase isozyme 1 (AMY1) double mutant Y105A/Y380A in complex with inhibitor acarbose
分子名称: Alpha-amylase type A isozyme, CALCIUM ION, beta-D-glucopyranose
著者Aghajari, N, Robert, X, Haser, R.
登録日2007-12-24
公開日2008-08-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Multi-site substrate binding and interplay in barley alpha-amylase 1
Febs Lett., 582, 2008
1AQH
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ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS
分子名称: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
著者Aghajari, N, Haser, R.
登録日1997-07-30
公開日1999-02-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
1AQM
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ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS COMPLEXED WITH TRIS
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-AMYLASE, CALCIUM ION, ...
著者Aghajari, N, Haser, R.
登録日1997-07-31
公開日1999-03-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
1G94
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CRYSTAL STRUCTURE ANALYSIS OF THE TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA AMYLASE FROM PSEUDOALTEROMONAS HALOPLANCTIS IN COMPLEX WITH A HEPTA-SACCHARIDE AND A TRIS MOLECULE
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Aghajari, N, Roth, M, Haser, R.
登録日2000-11-22
公開日2001-12-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase.
Biochemistry, 41, 2002
8ORP
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Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose
分子名称: 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Aghajari, N, Haser, R.
登録日2023-04-16
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.
Molecules, 28, 2023
8OR6
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Crystal structure of Drosophila melanogaster alpha-amylase
分子名称: Alpha-amylase A, CHLORIDE ION, STRONTIUM ION
著者Aghajari, N, Haser, R.
登録日2023-04-13
公開日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.
Molecules, 28, 2023
1G9H
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TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA-AMYLASE, COMII (PSEUDO TRI-SACCHARIDE FROM BAYER) AND TRIS (2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose, ALPHA-AMYLASE, ...
著者Aghajari, N, Roth, M, Haser, R.
登録日2000-11-23
公開日2002-06-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase.
Biochemistry, 41, 2002
5CR7
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Human cytosolic 5'-nucleotidase II in complex with N-(9H-Purin-6-yl)-3-(3-pyrrol-1-ylphenyl)benzamide
分子名称: ACETATE ION, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
著者Aghajari, N, Preeti, P.
登録日2015-07-22
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach.
J.Med.Chem., 58, 2015
2QPU
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Sugar tongs mutant S378P in complex with acarbose
分子名称: 1,2-ETHANEDIOL, 1,5-anhydro-4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-methylcyclohexyl]amino}-alpha-D-glucopyranosyl)-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
登録日2007-07-25
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
2QPS
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"Sugar tongs" mutant Y380A in complex with acarbose
分子名称: Alpha-amylase type A isozyme, CALCIUM ION
著者Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
登録日2007-07-25
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
1B0I
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ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS
分子名称: CALCIUM ION, CHLORIDE ION, PROTEIN (ALPHA-AMYLASE)
著者Aghajari, N, Haser, R.
登録日1998-11-10
公開日1999-11-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of the psychrophilic Alteromonas haloplanctis alpha-amylase give insights into cold adaptation at a molecular level.
Structure, 6, 1998
3BSG
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Barley alpha-amylase isozyme 1 (AMY1) H395A mutant
分子名称: Alpha-amylase type A isozyme, CALCIUM ION
著者Aghajari, N, Robert, X, Haser, R.
登録日2007-12-24
公開日2008-08-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Multi-site substrate binding and interplay in barley alpha-amylase 1
Febs Lett., 582, 2008
1JD9
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CRYSTAL STRUCTURE ANALYSIS OF THE MUTANT K300Q OF PSEUDOALTEROMONAS HALOPLANCTIS ALPHA-AMYLASE
分子名称: ALPHA-AMYLASE, CALCIUM ION
著者Aghajari, N, Haser, R.
登録日2001-06-13
公開日2002-09-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of alpha-amylase activation by chloride
PROTEIN SCI., 11, 2002
1JD7
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CRYSTAL STRUCTURE ANALYSIS OF THE MUTANT K300R OF PSEUDOALTEROMONAS HALOPLANCTIS ALPHA-AMYLASE
分子名称: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
著者Aghajari, N, Haser, R.
登録日2001-06-13
公開日2002-09-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of alpha-amylase activation by chloride
PROTEIN SCI., 11, 2002
8QZK
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Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4 Hexagonal form
分子名称: ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE
著者Aghajari, N, Hansen, A.L, Thiesen, F.F, Crehuet, R, Marcos, E, Willemoes, M.
登録日2023-10-27
公開日2024-03-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination.
Acs Synth Biol, 13, 2024
8QYE
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Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4
分子名称: 1,2-ETHANEDIOL, ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE
著者Aghajari, N.
登録日2023-10-25
公開日2024-03-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination.
Acs Synth Biol, 13, 2024
1L0P
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CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX BETWEEN PSYCHROPHILIC ALPHA AMYLASE FROM PSEUDOALTEROMONAS HALOPLANCTIS AND NITRATE
分子名称: ALPHA-AMYLASE, CALCIUM ION, NITRATE ION
著者Aghajari, N, Haser, R.
登録日2002-02-12
公開日2002-06-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of alpha-amylase activation by chloride.
Protein Sci., 11, 2002
1G9K
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CRYSTAL STRUCTURE OF A PSYCHROPHILIC ALKALINE PROTEASE FROM PSEUDOMONAS TAC II 18
分子名称: CALCIUM ION, SERRALYSIN, SULFATE ION, ...
著者Aghajari, N, Haser, R.
登録日2000-11-24
公開日2003-02-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold-adapted proteases
Proteins, 50, 2003
6FIW
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Human cytosolic 5'-nucleotidase II co-crystallized with 10mM Sodium ((4-(3'-((7H-purin-6-yl)carbamoyl)-[1,1'-biphenyl]-3-yl)-1H-imidazol-1-yl) methyl) phosphonate
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
著者Aghajari, N, Preeti, P.
登録日2018-01-19
公開日2019-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FIS
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Human cytosolic 5'-nucleotidase II soaked with 10mM 7-Benzyloxymethyl-7H-adenine
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
著者Aghajari, N, Preeti, P.
登録日2018-01-19
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FIR
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Human cytosolic 5'-nucleotidase II soaked with 5mM3-Phenyl-N-(9H-purin-6-yl)benzamide
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
著者Aghajari, N, Preeti, P.
登録日2018-01-19
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FIU
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Human cytosolic 5'-nucleotidase II soaked with 10mM 2-(6-([1,1'-Biphenyl]-3-carboxamido)-9H-purin-9-yl)acetic acid
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
著者Aghajari, N, Preeti, P.
登録日2018-01-19
公開日2019-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FXH
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Human cytosolic 5'-nucleotidase II soaked with 10mM 3-Phenyl-N-(9H-purin-6-yl)benzamide
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
著者Aghajari, N, Preeti, P.
登録日2018-03-09
公開日2019-03-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
1KXH
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Crystal structure of the complex between an inactive mutant of psychrophilic alpha-amylase (D174N) and acarbose
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Aghajari, N, Haser, R.
登録日2002-01-31
公開日2002-06-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase.
Biochemistry, 41
1H71
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Psychrophilic Protease from Pseudoalteromonas 'TAC II 18'
分子名称: CALCIUM ION, SERRALYSIN, ZINC ION
著者Villeret, V, Van Petegem, F, Aghajari, N, Chessa, J.-P, Gerday, C, Haser, R, Van Beeumen, J.
登録日2001-07-02
公開日2003-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of a Psychrophilic Metalloprotease Reveal New Insights Into Catalysis by Cold-Adapted Proteases
Proteins: Struct.,Funct., Genet., 50, 2003

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