1ANR
 
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1ARJ
 | | ARG-BOUND TAR RNA, NMR | | Descriptor: | ARGININE, TAR RNA | | Authors: | Aboul-Ela, F, Varani, G, Karn, J. | | Deposit date: | 1995-08-30 | | Release date: | 1996-11-08 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein.
J.Mol.Biol., 253, 1995
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1FQZ
 | | NMR VALIDATED MODEL OF DOMAIN IIID OF HEPATITIS C VIRUS INTERNAL RIBOSOME ENTRY SITE | | Descriptor: | HEPATITIS C VIRUS IRES DOMAIN IIID | | Authors: | Klinck, R, Westhof, E, Walker, S, Afshar, M, Collier, A, Aboul-ela, F. | | Deposit date: | 2000-09-07 | | Release date: | 2001-01-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.
RNA, 6, 2000
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1KP7
 | | Conserved RNA Structure within the HCV IRES eIF3 Binding Site | | Descriptor: | Hepatitis C Virus Internal Ribosome Entry Site Fragment | | Authors: | Gallego, J, Klinck, R, Collier, A.J, Cole, P.T, Harris, S.J, Harrison, G.P, Aboul-ela, F, Walker, S, Varani, G. | | Deposit date: | 2001-12-29 | | Release date: | 2002-04-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A conserved RNA structure within the HCV IRES eIF3-binding site.
Nat.Struct.Biol., 9, 2002
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1UUI
 | | NMR structure of a synthetic small molecule, rbt158, bound to HIV-1 TAR RNA | | Descriptor: | 4-[AMINO(IMINO)METHYL]-1-[2-(3-AMMONIOPROPOXY)-5-METHOXYBENZYL]PIPERAZIN-1-IUM, 5'-R(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP* CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C)-3' | | Authors: | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | | Deposit date: | 2003-12-19 | | Release date: | 2004-02-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
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1UUD
 | | NMR structure of a synthetic small molecule, rbt203, bound to HIV-1 TAR RNA | | Descriptor: | N-[2-(2-{[(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)AMINO]METHYL}-4-METHOXYPHENOXY)ETHYL]GUANIDINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3') | | Authors: | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | | Deposit date: | 2003-12-18 | | Release date: | 2004-03-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
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1OLN
 | | Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA | | Descriptor: | 50S RIBOSOMAL PROTEIN L11, RNA, THIOSTREPTON | | Authors: | Lentzen, G, Klinck, R, Matassova, N, Aboul-Ela, F, Murchie, A.I.H. | | Deposit date: | 2003-08-08 | | Release date: | 2003-09-11 | | Last modified: | 2019-08-21 | | Method: | SOLUTION NMR, THEORETICAL MODEL | | Cite: | Structural Basis for Contrasting Activities of Ribosome Binding Thiazole Antibiotics
Chem.Biol., 10, 2003
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1UTS
 | | Designed HIV-1 TAR Binding Ligand | | Descriptor: | N-[2-(3-AMINOPROPOXY)-5-(1H-INDOL-5-YL)BENZYL]-N-(2-PIPERAZIN-1-YLETHYL)AMINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3') | | Authors: | Davis, B, Murchie, A.I.H, Aboul-Ela, F, Karn, J. | | Deposit date: | 2003-12-10 | | Release date: | 2004-02-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA.
J.Mol.Biol., 336, 2004
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