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PDB: 1209 件

2FRF
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Horse Heart Myoglobin, Nitrite Adduct, Crystal Soak
分子名称: Myoglobin, NITRITE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Copeland, D.M, Soares, A.S, West, A.H, Richter-Addo, G.B.
登録日2006-01-19
公開日2006-05-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin.
J.Inorg.Biochem., 100, 2006
2FRK
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Nitrosyl Horse Heart Myoglobin, Nitric Oxide Gas Method
分子名称: Myoglobin, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Copeland, D.M, Soares, A.S, West, A.H, Richter-Addo, G.B.
登録日2006-01-19
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin.
J.Inorg.Biochem., 100, 2006
2FUK
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Crystal structure of XC6422 from Xanthomonas campestris: a member of a/b serine hydrolase without lid at 1.6 resolution
分子名称: XC6422 protein
著者Yang, C.Y, Chin, K.H, Chou, C.C, Wang, A.H.J, Chou, S.H.
登録日2006-01-27
公開日2006-07-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of XC6422 from Xanthomonas campestris at 1.6 A resolution: a small serine alpha/beta-hydrolase
Acta Crystallogr.,Sect.F, 62, 2006
2FRJ
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Nitrosyl Horse Heart Myoglobin, Nitrite/Dithionite Method
分子名称: Myoglobin, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Copeland, D.M, Soares, A.S, West, A.H, Richter-Addo, G.B.
登録日2006-01-19
公開日2006-05-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin.
J.Inorg.Biochem., 100, 2006
2GBZ
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The Crystal Structure of XC847 from Xanthomonas campestris: a 3-5 Oligoribonuclease of DnaQ fold family with a Novel Opposingly-Shifted Helix
分子名称: MAGNESIUM ION, Oligoribonuclease
著者Chin, K.H, Yang, C.Y, Chou, C.C, Wang, A.H.J, Chou, S.H.
登録日2006-03-12
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of XC847 from Xanthomonas campestris: a 3'-5' oligoribonuclease of DnaQ fold family with a novel opposingly shifted helix
Proteins, 65, 2006
7JK7
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Crystal structure of Importin alpha 2 in complex with LSD1 NLS S111E mutant
分子名称: GLYCEROL, Importin subunit alpha-1, Lysine-specific histone demethylase 1A
著者Tu, W.J, McCuaig, R, Tan, A.H.Y, Hardy, K, Seddiki, N, Ali, S, Dahlstron, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S.
登録日2020-07-27
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.
Front Immunol, 11, 2020
7JNO
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X-ray crystallographic structure of the NS3 helicase domain from Tick-borne encephalitis virus
分子名称: Serine protease NS3
著者Weeks, S.D, Munwar, A, Lucero, H.A, Bandara, A, Munawar, A.H.
登録日2020-08-05
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Tickborne Encephalitis Virus NS3-Helicase and implications for drug design
To Be Published
7K7T
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Crystal structure of human MORC4 ATPase-CW in complex with AMPPNP
分子名称: Isoform 3 of MORC family CW-type zinc finger protein 4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Klein, B.J, Tencer, A.H, Kutateladze, T.G.
登録日2020-09-24
公開日2020-11-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Molecular mechanism of the MORC4 ATPase activation.
Nat Commun, 11, 2020
7KBY
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Artificial Metalloproteins with Dinuclear Iron Centers
分子名称: ACETATE ION, CYANIDE ION, Streptavidin, ...
著者Miller, K.R, Follmer, A.H, Jasniewski, A.J, Sabuncu, S, Biswas, S, Albert, T, Hendrich, M.P, Moenne-Loccoz, P, Borovik, A.S.
登録日2020-10-03
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers.
J.Am.Chem.Soc., 143, 2021
7KBZ
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Artificial Metalloproteins with Dinuclear Iron Centers
分子名称: CYANIDE ION, Streptavidin, {N-(4-{bis[(pyridin-2-yl-kappaN)methyl]amino-kappaN}butyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}iron(3+)
著者Miller, K.R, Follmer, A.H, Jasniewski, A.J, Sabuncu, S, Biswas, S, Albert, T, Hendrich, M.P, Moenne-Loccoz, P, Borovik, A.S.
登録日2020-10-03
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers.
J.Am.Chem.Soc., 143, 2021
7LHB
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Crystal structure of Bcl-2 in complex with prodrug ABBV-167
分子名称: Apoptosis regulator Bcl-2, Phosphoric acid mono-[5-(5-{4-[2-(4-chloro-phenyl)-4,4-dimethyl-cyclohex-1-enylmethyl]-piperazin-1-yl}-2-{3-nitro-4-[(tetrahydro-pyran-4-ylmethyl)-amino]-benzenesulfonylaminocarbonyl}-phenoxy)-pyrrolo[2,3-b]pyridin-7-ylmethyl] ester
著者Judge, R.A, Salem, A.H.
登録日2021-01-21
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.068 Å)
主引用文献Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers.
Mol.Cancer Ther., 20, 2021
7KNL
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Artificial Metalloproteins with Dinuclear Iron Centers
分子名称: Streptavidin
著者Miller, K.R, Follmer, A.H, Jasniewski, A.J, Sabuncu, S, Biswas, S, Albert, T, Biswas, A, Hendrich, M.P, Moenne-Loccoz, P, Borovik, A.S.
登録日2020-11-04
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers.
J.Am.Chem.Soc., 143, 2021
8GMB
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Crystal structure of the full-length Bruton's tyrosine kinase (PH-TH domain not visible)
分子名称: 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, Tyrosine-protein kinase BTK
著者Lin, D.Y, Andreotti, A.H.
登録日2023-03-24
公開日2023-08-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states.
Elife, 12, 2024
8GCR
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HPV16 E6-E6AP-p53 complex
分子名称: Cellular tumor antigen p53, Maltose/maltodextrin-binding periplasmic protein,Protein E6, Ubiquitin-protein ligase E3A, ...
著者Bratkowski, M.A, Wang, J.C.K, Hao, Q, Nile, A.H.
登録日2023-03-02
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structure of the p53 degradation complex from HPV16.
Nat Commun, 15, 2024
8I4F
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Omicron spike variant XBB with n3130v-Fc
分子名称: Spike glycoprotein, n3130v-Fc
著者Hao, A.H, Zhang, X, Chen, Z.G, Sun, L.
登録日2023-01-19
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Signal Transduct Target Ther, 8, 2023
8I4G
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Omicron spike variant BQ.1.1 with n3130v-Fc
分子名称: Spike glycoprotein, n3130v-Fc
著者Hao, A.H, Zhang, X, Chen, Z.G, Sun, L.
登録日2023-01-19
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Signal Transduct Target Ther, 8, 2023
8I4E
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Omicron spike variant XBB with Bn03
分子名称: Bn03, Spike glycoprotein
著者Hao, A.H, Zhang, X, Chen, Z.G, Sun, L.
登録日2023-01-19
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Signal Transduct Target Ther, 8, 2023
8I4H
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Omicron spike variant BA.1 with Bn03
分子名称: Bn03, Spike glycoprotein
著者Hao, A.H, Zhang, X, Chen, Z.G, Sun, L.
登録日2023-01-19
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Signal Transduct Target Ther, 8, 2023
8JA2
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ASFV Topoisomerase ATPase domain in complex with AMP-PNP and Mg2+
分子名称: DNA topoisomerase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Pang, A.H, Chang, C.-W, Tsai, M.-D.
登録日2023-05-05
公開日2024-02-07
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A unified view on enzyme catalysis by cryo-EM study of a DNA topoisomerase.
Commun Chem, 7, 2024
8JA1
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ASFV Topoisomerase ATPase domain in complex with AMP-PNP and Mg2+ (oxidized form)
分子名称: DNA topoisomerase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Chang, C.-W, Pang, A.H, Tsai, M.-D.
登録日2023-05-05
公開日2024-02-07
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献A unified view on enzyme catalysis by cryo-EM study of a DNA topoisomerase.
Commun Chem, 7, 2024
8KB6
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Crystal Structure of Canine TNF-alpha
分子名称: Tumor necrosis factor
著者Lee, C.C, Wang, A.H.-J.
登録日2023-08-03
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.850166 Å)
主引用文献Structure-based development of a canine TNF-alpha-specific antibody using adalimumab as a template.
Protein Sci., 33, 2024
1VTJ
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MOLECULAR STRUCTURE OF THE NETROPSIN-D(CGCGATATCGCG) COMPLEX: DNA CONFORMATION IN AN ALTERNATING AT SEGMENT; CONFORMATION 1
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*TP*CP*GP*CP*G)-3'), NETROPSIN
著者Coll, M, Aymami, J, Van Der Marel, G.A, Van Boom, J.H, Rich, A, Wang, A.H.-J.
登録日1999-09-14
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Structure of the Netropsin-d(CGCGATATCGCG) Complex: DNA Conformation in an Alternating AT Segment
Biochemistry, 28, 1989
1VTV
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Molecular structure of (M5DC-DG)3: The role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA
分子名称: DNA (5'-D(*(CH3)CP*GP*(CH3)CP*GP*(CH3)CP*G)-3')
著者Fujii, S, Wang, A.H.-J, Van Der Marel, G.A, Van Boom, J.H, Rich, A.
登録日1989-01-10
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Molecular Structure of (m5dC-dG)3: The Role of the Methyl Group on 5-Methyl Cytosine in Stabilizing Z-DNA
Nucleic Acids Res., 10, 1982
1VTC
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MOLECULAR STRUCTURE OF THE OCTAMER D(G-G-C-C-G-G-C-C) MODIFIED A-DNA
分子名称: DNA (5'-D(*GP*GP*CP*CP*GP*GP*CP*C)-3')
著者Wang, A.H.-J, Fujii, S, Van Boom, J.H, Rich, A.
登録日1988-08-18
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular Structure of the Octamer d(G-G-C-C-G-G-C-C) Modified A-DNA
Proc.Natl.Acad.Sci.USA, 79, 1982
1VTW
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AT Base Pairs Are Less Stable than GC Base Pairs in Z-DNA: The Crystal Structure of D(M(5)CGTAM(5)CG)
分子名称: DNA (5'-D(*(CH3)CP*GP*TP*AP*(CH3)CP*G)-3')
著者Wang, A.H.-J, Hakoshima, T, Van Der Marel, G.A, Van Boom, J.H, Rich, A.
登録日1988-08-18
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献AT Base Pairs Are Less Stable than GC Base Pairs in Z-DNA: The Crystal Structure of d(m(5)CGTAm(5)CG)
Cell(Cambridge,Mass.), 37, 1984

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