6W25
| Crystal structure of the Melanocortin-4 Receptor (MC4R) in complex with SHU9119 | 分子名称: | CALCIUM ION, Melanocortin receptor 4,GlgA glycogen synthase,Melanocortin receptor 4, OLEIC ACID, ... | 著者 | Yu, J, Gimenez, L.E, Hernandez, C.C, Wu, Y, Wein, A.H, Han, G.W, McClary, K, Mittal, S.R, Burdsall, K, Stauch, B, Wu, L, Stevens, S.N, Peisley, A, Williams, S.Y, Chen, V, Millhauser, G.L, Zhao, S, Cone, R.D, Stevens, R.C. | 登録日 | 2020-03-04 | 公開日 | 2020-04-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Determination of the melanocortin-4 receptor structure identifies Ca2+as a cofactor for ligand binding. Science, 368, 2020
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5HXT
| Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with IPP and DMSPP | 分子名称: | (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... | 著者 | Lee, C.C, Chan, Y.T, Wang, A.H.J. | 登録日 | 2016-01-31 | 公開日 | 2017-04-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase Acs Omega, 2, 2017
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6VO9
| Artificial Metalloproteins with Dinuclear Iron Centers | 分子名称: | ACETATE ION, Streptavidin, {N-(4-{bis[(pyridin-2-yl-kappaN)methyl]amino-kappaN}butyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}iron(3+) | 著者 | Miller, K.R, Follmer, A.H, Jasniewski, A.J, Sabuncu, S, Biswas, S, Albert, T, Hendrich, M.P, Moenne-Loccoz, P, Borovik, A.S. | 登録日 | 2020-01-30 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Artificial Metalloproteins with Dinuclear Iron-Hydroxido Centers. J.Am.Chem.Soc., 143, 2021
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5HXQ
| Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with DMSPP | 分子名称: | (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... | 著者 | Lee, C.C, Chan, Y.T, Wang, A.H.J. | 登録日 | 2016-01-31 | 公開日 | 2017-04-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase Acs Omega, 2, 2017
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5HXP
| Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with IPP | 分子名称: | (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... | 著者 | Lee, C.C, Chan, Y.T, Wang, A.H.J. | 登録日 | 2016-01-31 | 公開日 | 2017-04-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase. Acs Omega, 2, 2017
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6X4C
| Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)-4-fluorophenoxy)-5,8-dimethyl-2-naphthonitrile (JLJ658), a Non-nucleoside Inhibitor | 分子名称: | 7-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-5,8-dimethylnaphthalene-2-carbonitrile, Reverse transcriptase/ribonuclease H, p51 RT | 著者 | Chan, A.H, Duong, V.N, Ippolito, J.A, Jorgensen, W.L, Anderson, K.S. | 登録日 | 2020-05-22 | 公開日 | 2020-07-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.861 Å) | 主引用文献 | Structural investigation of 2-naphthyl phenyl ether inhibitors bound to WT and Y181C reverse transcriptase highlights key features of the NNRTI binding site. Protein Sci., 29, 2020
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1QSP
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1QZP
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5TW3
| Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)-4-fluorophenoxy)-7-fluoro-2-naphthonitrile (JLJ636), a Non-nucleoside Inhibitor | 分子名称: | 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-7-fluoronaphthalene-2-carbonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... | 著者 | Chan, A.H, Anderson, K.S. | 登録日 | 2016-11-11 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.853 Å) | 主引用文献 | Structural and Preclinical Studies of Computationally Designed Non-Nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection. Mol. Pharmacol., 91, 2017
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1QG4
| CANINE GDP-RAN F72Y MUTANT | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN) | 著者 | Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M. | 登録日 | 1999-04-20 | 公開日 | 1999-06-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import. J.Mol.Biol., 289, 1999
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1OXB
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5TG3
| Crystal Structure of Dioclea reflexa seed lectin (DrfL) in complex with X-Man | 分子名称: | 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, Dioclea reflexa lectin, ... | 著者 | Santiago, M.Q, Correia, J.L.A, Pinto-Junior, V.R, Osterne, V.J.S, Pereira, R.I, Silva-Filho, J.C, Lossio, C.F, Rocha, B.A.M, Delatorre, P, Neco, A.H.B, Araripe, D.A, Nascimento, K.S, Cavada, B.S. | 登録日 | 2016-09-27 | 公開日 | 2017-02-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.765 Å) | 主引用文献 | Structural studies of a vasorelaxant lectin from Dioclea reflexa Hook seeds: Crystal structure, molecular docking and dynamics. Int. J. Biol. Macromol., 98, 2017
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1PZ0
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5URV
| Crystal structure of Frizzled 7 CRD in complex with C24 fatty acid | 分子名称: | (15E)-TETRACOS-15-ENOIC ACID, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mukund, S, Nile, A.H, Stanger, K, Hannoush, R.N, Wang, W. | 登録日 | 2017-02-13 | 公開日 | 2017-05-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5URZ
| Crystal structure of Frizzled 5 CRD in complex with BOG | 分子名称: | Frizzled-5, alpha-L-fucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, octyl beta-D-glucopyranoside | 著者 | Mukund, S, Nile, A.H, Stanger, K, Hannoush, R.N, Wang, W. | 登録日 | 2017-02-13 | 公開日 | 2017-05-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1PYF
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1RZ1
| Reduced flavin reductase PheA2 in complex with NAD | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, phenol 2-hydroxylase component B | 著者 | Van Den Heuvel, R.H, Westphal, A.H, Heck, A.J, Walsh, M.A, Rovida, S, Van Berkel, W.J, Mattevi, A. | 登録日 | 2003-12-23 | 公開日 | 2004-04-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Studies on Flavin Reductase PheA2 Reveal Binding of NAD in an Unusual Folded Conformation and Support Novel Mechanism of Action. J.Biol.Chem., 279, 2004
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1S1G
| Crystal Structure of Kv4.3 T1 Domain | 分子名称: | Potassium voltage-gated channel subfamily D member 3, ZINC ION | 著者 | Scannevin, R.H, Wang, K.W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.X, Xu, Z.B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2004-03-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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8TY0
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1PZ1
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5UUY
| Crystal structure of Dioclea lasiocarpa lectin (DLL) complexed with X-MAN | 分子名称: | 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, Dioclea lasiocarpa lectin (DLL), ... | 著者 | Santiago, M.Q, Pinto-Junior, V.R, Osterne, V.J.S, Rocha, C.R.C, Neco, A.H.B, Fonseca, F.M.P, Nascimento, K.S, Cavada, B.S. | 登録日 | 2017-02-17 | 公開日 | 2017-10-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural analysis of Dioclea lasiocarpa lectin: A C6 cells apoptosis-inducing protein. Int. J. Biochem. Cell Biol., 92, 2017
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1PM4
| Crystal structure of Yersinia pseudotuberculosis-derived mitogen (YPM) | 分子名称: | YPM | 著者 | Donadini, R, Liew, C.W, Kwan, A.H, Mackay, J.P, Fields, B.A. | 登録日 | 2003-06-09 | 公開日 | 2004-01-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | 主引用文献 | Crystal and Solution Structures of a Superantigen from Yersinia pseudotuberculosis Reveal a Jelly-Roll Fold. Structure, 12, 2004
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1POQ
| Solution Structure of a Superantigen from Yersinia pseudotuberculosis | 分子名称: | YPM | 著者 | Donadini, R, Liew, C.W, Kwan, A.H, Mackay, J.P, Fields, B.A. | 登録日 | 2003-06-16 | 公開日 | 2004-01-27 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Crystal and Solution Structures of a Superantigen from Yersinia pseudotuberculosis Reveal a Jelly-Roll Fold. Structure, 12, 2004
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128D
| MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG) COMPLEXED WITH HOECHST 33258 | 分子名称: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3') | 著者 | Sriram, M, Van Der Marel, G.A, Roelen, H.L.P.F, Van Boom, J.H, Wang, A.H.-J. | 登録日 | 1993-06-30 | 公開日 | 1994-01-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342. EMBO J., 11, 1992
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129D
| DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') COMPLEXED WITH HOECHST 33342 | 分子名称: | 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | 著者 | Sriram, M, Van Der Marel, G.A, Roelen, H.L.P.F, Van Boom, J.H, Wang, A.H.-J. | 登録日 | 1993-06-30 | 公開日 | 1994-01-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342. EMBO J., 11, 1992
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