6FDI
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![BU of 6fdi by Molmil](/molmil-images/mine/6fdi) | Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-226 | Descriptor: | 1,2-ETHANEDIOL, 1-[2-[4-[(4~{a}~{S},8~{a}~{R})-4-(3,4-dimethoxyphenyl)-1-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-2-yl]piperi din-1-yl]-2-oxidanylidene-ethyl]-4,4-dimethyl-piperidine-2,6-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Singh, A.K, Brown, D.G. | Deposit date: | 2017-12-24 | Release date: | 2019-04-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | hPDE4D2 structure with inhibitor NPD-226 To be published
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6PHW
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![BU of 6phw by Molmil](/molmil-images/mine/6phw) | SpAga D472N structure in complex with melibiose | Descriptor: | 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID, ... | Authors: | Pluvinage, B, Boraston, A.B. | Deposit date: | 2019-06-25 | Release date: | 2019-10-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
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6SR0
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![BU of 6sr0 by Molmil](/molmil-images/mine/6sr0) | X-ray pump X-ray probe on lysozyme.Gd nanocrystals: single colour reference data | Descriptor: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, CHLORIDE ION, GADOLINIUM ATOM, ... | Authors: | Kloos, M, Gorel, A, Nass, K. | Deposit date: | 2019-09-04 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural dynamics in proteins induced by and probed with X-ray free-electron laser pulses. Nat Commun, 11, 2020
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6F0D
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![BU of 6f0d by Molmil](/molmil-images/mine/6f0d) | Crystal structure of a llama VHH antibody BCD090-M2 against human ErbB3 in space group P1 with cadmium ions | Descriptor: | CADMIUM ION, VHH antibody BCD090-M2 | Authors: | Eliseev, I.E, Yudenko, A.N, Vysochinskaya, V.V, Svirina, A.A, Evstratyeva, A.V, Drozhzhachih, M.S, Krendeleva, E.A, Vladimirova, A.K, Nemankin, T.A, Ekimova, V.M, Ulitin, A.B, Lomovskaya, M.I, Yakovlev, P.A, Moiseenko, F.V, Chakchir, O.B. | Deposit date: | 2017-11-19 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.90000749 Å) | Cite: | Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor. F1000Res, 7, 2018
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6YR6
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![BU of 6yr6 by Molmil](/molmil-images/mine/6yr6) | 14-3-3 sigma in complex with hDM2-186 peptide | Descriptor: | 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IODIDE ION, ... | Authors: | Wolter, M, Srdanovic, S, Warriner, S, Wilson, A, Ottmann, C. | Deposit date: | 2020-04-19 | Release date: | 2021-11-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study. Febs J., 2022
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6YR7
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![BU of 6yr7 by Molmil](/molmil-images/mine/6yr7) | 14-3-3 sigma in complex with hDMX-342+367 peptide | Descriptor: | 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Protein Mdm4 | Authors: | Wolter, M, Srdanovic, S, Warriner, S, Wilson, A, Ottmann, C. | Deposit date: | 2020-04-19 | Release date: | 2021-11-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study. Febs J., 2022
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6YR5
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![BU of 6yr5 by Molmil](/molmil-images/mine/6yr5) | 14-3-3 sigma in complex with hDMX-367 peptide | Descriptor: | 14-3-3 protein sigma, Protein Mdm4, SULFATE ION | Authors: | Wolter, M, Srdanovic, S, Ottman, C, Warriner, S, Wilson, A. | Deposit date: | 2020-04-19 | Release date: | 2021-11-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study. Febs J., 2022
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6SR2
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![BU of 6sr2 by Molmil](/molmil-images/mine/6sr2) | X-ray pump X-ray probe on lysozyme.Gd nanocrystals: 37 fs time delay | Descriptor: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, CHLORIDE ION, GADOLINIUM ATOM, ... | Authors: | Kloos, M, Gorel, A, Nass, K. | Deposit date: | 2019-09-04 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural dynamics in proteins induced by and probed with X-ray free-electron laser pulses. Nat Commun, 11, 2020
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8FFV
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![BU of 8ffv by Molmil](/molmil-images/mine/8ffv) | Cryo-EM structure of the GR-Hsp90-FKBP52 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... | Authors: | Noddings, C.M, Agard, D.A. | Deposit date: | 2022-12-10 | Release date: | 2023-11-01 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
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8CWH
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![BU of 8cwh by Molmil](/molmil-images/mine/8cwh) | 200us Temperature-Jump (Dark2) XFEL structure of Lysozyme Bound to N,N'-diacetylchitobiose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... | Authors: | Wolff, A.M, Thompson, M.C, Fraser, J.S, Nango, E. | Deposit date: | 2022-05-19 | Release date: | 2022-06-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography. Nat.Chem., 15, 2023
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6PPO
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![BU of 6ppo by Molmil](/molmil-images/mine/6ppo) | Rhinovirus C15 complexed with domain I of receptor CDHR3 | Descriptor: | CALCIUM ION, Cadherin-related family member 3, Capsid protein VP1, ... | Authors: | Sun, Y, Watters, K, Klose, T, Palmenberg, A.C. | Deposit date: | 2019-07-08 | Release date: | 2020-03-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor. Proc.Natl.Acad.Sci.USA, 117, 2020
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6STB
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![BU of 6stb by Molmil](/molmil-images/mine/6stb) | Crystal structure of the strawberry pathogenesis-related 10 (PR-10) Fra a 1.02 protein, Q64W mutant | Descriptor: | Major strawberry allergen Fra a 1-2 | Authors: | Orozco-Navarrete, B, Kaczmarska, Z, Dupeux, F, Pott, D, Diaz Perales, A, Casanal, A, Marquez, J.A, Valpuesta, V, Merchante, C. | Deposit date: | 2019-09-10 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structural Bases for the Allergenicity of Fra a 1.02 in Strawberry Fruits. J.Agric.Food Chem., 68, 2020
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6VF2
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![BU of 6vf2 by Molmil](/molmil-images/mine/6vf2) | DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mg2+ (960 min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-01-03 | Release date: | 2021-09-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mg2+ (960 min) To be published
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7O4B
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![BU of 7o4b by Molmil](/molmil-images/mine/7o4b) | |
4YD1
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![BU of 4yd1 by Molmil](/molmil-images/mine/4yd1) | Ternary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate and an incoming nonhydrolyzable dUMPNPP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Moon, A.F, Gosavi, R.A, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | Deposit date: | 2015-02-20 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Creative template-dependent synthesis by human polymerase mu. Proc.Natl.Acad.Sci.USA, 112, 2015
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5MV7
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![BU of 5mv7 by Molmil](/molmil-images/mine/5mv7) | Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain | Descriptor: | SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb | Authors: | Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A. | Deposit date: | 2017-01-15 | Release date: | 2017-07-05 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
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6VF8
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![BU of 6vf8 by Molmil](/molmil-images/mine/6vf8) | DNA Polymerase Mu, 8-oxorGTP:Ct Pre-Catalytic Ternary Complex, 20 mM Ca2+ (120 min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-01-03 | Release date: | 2021-09-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | DNA Polymerase Mu, 8-oxorGTP:Ct Pre-Catalytic Ternary Complex, 20 mM Ca2+ (120 min) To be published
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6VF4
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![BU of 6vf4 by Molmil](/molmil-images/mine/6vf4) | DNA Polymerase Mu, 8-oxorGTP:At Reaction State Ternary Complex, 50 mM Mn2+ (30 min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-01-03 | Release date: | 2021-09-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | DNA Polymerase Mu, 8-oxorGTP:At Reaction State Ternary Complex, 50 mM Mn2+ (30 min) To be published
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6YHZ
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![BU of 6yhz by Molmil](/molmil-images/mine/6yhz) | |
6MLM
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![BU of 6mlm by Molmil](/molmil-images/mine/6mlm) | H7 HA0 in complex with Fv from H7.5 IgG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fv of H7.5 Fab, Hemagglutinin HA1 chain, ... | Authors: | Pallesen, J, Turner, H.L, Ward, A.B. | Deposit date: | 2018-09-27 | Release date: | 2019-02-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. PLoS Biol., 17, 2019
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6VEZ
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![BU of 6vez by Molmil](/molmil-images/mine/6vez) | DNA Polymerase Mu, 8-oxorGTP:At Pre-Catalytic Ternary Complex, 20 mM Ca2+ (60 min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-01-03 | Release date: | 2021-09-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.875 Å) | Cite: | DNA Polymerase Mu, 8-oxorGTP:At Pre-Catalytic Ternary Complex, 20 mM Ca2+ (60 min) To be published
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6YI2
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![BU of 6yi2 by Molmil](/molmil-images/mine/6yi2) | |
6VF6
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![BU of 6vf6 by Molmil](/molmil-images/mine/6vf6) | DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mn2+ (960 min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-01-03 | Release date: | 2021-09-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mn2+ (960 min) To be published
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6VF5
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![BU of 6vf5 by Molmil](/molmil-images/mine/6vf5) | DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mn2+ (120 min) | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Jamsen, J.A, Wilson, S.H. | Deposit date: | 2020-01-03 | Release date: | 2021-09-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | DNA Polymerase Mu, 8-oxorGTP:At Product State Ternary Complex, 50 mM Mn2+ (120 min) To be published
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8CWG
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![BU of 8cwg by Molmil](/molmil-images/mine/8cwg) | 200us Temperature-Jump (Dark1) XFEL structure of Lysozyme Bound to N,N'-diacetylchitobiose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... | Authors: | Wolff, A.M, Thompson, M.C, Fraser, J.S, Nango, E. | Deposit date: | 2022-05-19 | Release date: | 2022-06-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography. Nat.Chem., 15, 2023
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