6RH0
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![BU of 6rh0 by Molmil](/molmil-images/mine/6rh0) | Revisiting pH-gated conformational switch. Complex HK853-RR468 pH 5.5 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Response regulator, ... | 著者 | Mideros-Mora, C, Casino, P, Marina, A. | 登録日 | 2019-04-18 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases. Nat Commun, 11, 2020
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5K4G
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5K50
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![BU of 5k50 by Molmil](/molmil-images/mine/5k50) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ and L-allo-threonine refined to 2.23 angstroms | 分子名称: | ACETATE ION, ALLO-THREONINE, GLYCEROL, ... | 著者 | Adjogatse, E.A, Erskine, P.T, Cooper, J.B. | 登録日 | 2016-05-22 | 公開日 | 2017-11-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
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6EIY
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![BU of 6eiy by Molmil](/molmil-images/mine/6eiy) | Crystal structure of KDM5B in complex with KDOPZ000034a. | 分子名称: | 1,2-ETHANEDIOL, 2-chloranyl-~{N}-[2-[4-(3-cyano-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidin-5-yl)pyrazol-1-yl]ethyl]ethanamide, DIMETHYL SULFOXIDE, ... | 著者 | Srikannathasan, V, Newman, J.A, Szykowska, A, Wright, M, Ruda, G.F, Vazquez-Rodriguez, S.A, Kupinska, K, Strain-Damerell, C, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Huber, K, von Delft, F. | 登録日 | 2017-09-19 | 公開日 | 2018-05-02 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of KDM5B in complex with KDOPZ000034a. to be published
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7ASD
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![BU of 7asd by Molmil](/molmil-images/mine/7asd) | Structure of native royal jelly filaments | 分子名称: | (3beta,14beta,17alpha)-ergosta-5,24(28)-dien-3-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mattei, S, Ban, A, Picenoni, A, Leibundgut, M, Glockshuber, R, Boehringer, D. | 登録日 | 2020-10-27 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of native glycolipoprotein filaments in honeybee royal jelly. Nat Commun, 11, 2020
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8JCQ
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5K68
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![BU of 5k68 by Molmil](/molmil-images/mine/5k68) | Designed Artificial Cupredoxins | 分子名称: | Streptavidin, [CuII(biot-bu-dpea)]2+ | 著者 | Mann, S.I, Heinisch, T, Weitz, A.C, Hendrich, M.R, Ward, T.R, Borovik, A.S. | 登録日 | 2016-05-24 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Modular Artificial Cupredoxins. J.Am.Chem.Soc., 138, 2016
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5GJG
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![BU of 5gjg by Molmil](/molmil-images/mine/5gjg) | Crystal structure of human TAK1/TAB1 fusion protein in complex with ligand 4 | 分子名称: | N-(2-isopropoxy-4-(4-methylpiperazine-1-carbonyl)phenyl)-2-(3-(phenylcarbamoyl)phenyl)thiazole-4-carboxamide, TAK1 kinase - TAB1 chimera fusion protein | 著者 | Irie, M, Nakamura, M, Fukami, T.A, Matsuura, T, Morishima, K. | 登録日 | 2016-06-29 | 公開日 | 2016-11-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Development of a Method for Converting a TAK1 Type I Inhibitor into a Type II or c-Helix-Out Inhibitor by Structure-Based Drug Design (SBDD) Chem.Pharm.Bull., 64, 2016
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8JCS
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6IV3
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8UP3
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![BU of 8up3 by Molmil](/molmil-images/mine/8up3) | Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21F) | 分子名称: | 1,2-ETHANEDIOL, ASPARTIC ACID, Asparaginase, ... | 著者 | Lubkowski, J, Wlodawer, A, Zhang, D. | 登録日 | 2023-10-20 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases. Protein Sci., 33, 2024
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6RIH
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8UPC
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![BU of 8upc by Molmil](/molmil-images/mine/8upc) | Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K158M) | 分子名称: | Asparaginase, CHLORIDE ION, GLYCEROL | 著者 | Lubkowski, J, Wlodawer, A, Zhang, D. | 登録日 | 2023-10-22 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases. Protein Sci., 33, 2024
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8UP6
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![BU of 8up6 by Molmil](/molmil-images/mine/8up6) | Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K19A) in complex with L-Asp | 分子名称: | ASPARTIC ACID, Asparaginase, TETRAETHYLENE GLYCOL | 著者 | Lubkowski, J, Wlodawer, A, Zhang, D. | 登録日 | 2023-10-21 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases. Protein Sci., 33, 2024
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4R9X
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![BU of 4r9x by Molmil](/molmil-images/mine/4r9x) | Crystal Structure of Putative Copper Homeostasis Protein CutC from Bacillus anthracis | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Copper homeostasis protein CutC, ... | 著者 | Kim, Y, Zhou, M, Makowska-Grzyska, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-09-08 | 公開日 | 2014-09-17 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8515 Å) | 主引用文献 | Crystal Structure of Putative Copper Homeostasis Protein CutC
from Bacillus anthracis To be Published, 2014
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8EAG
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![BU of 8eag by Molmil](/molmil-images/mine/8eag) | SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 2 | 分子名称: | 12-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | 著者 | Meagher, M, Myasnikov, A, Enemark, E.J. | 登録日 | 2022-08-29 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
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5X6Y
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6RIC
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![BU of 6ric by Molmil](/molmil-images/mine/6ric) | Structure of the core Vaccinia Virus DNA-dependent RNA polymerase complex | 分子名称: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | 著者 | Grimm, C, Hillen, H.S, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A, Cramer, P, Fischer, U. | 登録日 | 2019-04-23 | 公開日 | 2019-12-18 | 最終更新日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell, 179, 2019
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6E6K
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![BU of 6e6k by Molmil](/molmil-images/mine/6e6k) | Crystal structure of human cellular retinol-binding protein 4 in complex with abnormal-cannabidiol (abn-CBD) | 分子名称: | (1'R,2'R)-5'-methyl-6-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro[1,1'-biphenyl]-2,4-diol, Retinoid-binding protein 7 | 著者 | Silvaroli, J.A, Banerjee, S, Kiser, P.D, Golczak, M. | 登録日 | 2018-07-25 | 公開日 | 2019-02-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1. Acs Chem.Biol., 14, 2019
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6ALS
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![BU of 6als by Molmil](/molmil-images/mine/6als) | Solution structure of a DNA dodecamer with 5-methylcytosine at the 3rd and 9th position and 8-oxoguanine at the 4th position | 分子名称: | DNA (5'-D(*(DC5)P*GP*(DMC)P*(8OG)P*AP*AP*TP*TP*(DMC)P*GP*CP*(DG3))-3') | 著者 | Gruber, D.R, Shernyukov, A.V, Endutkin, A.V, Bagryanskaya, E.G, Zharkov, D.O, Smirnov, S.L. | 登録日 | 2017-08-08 | 公開日 | 2017-09-06 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation. Nucleic Acids Res., 46, 2018
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5KAR
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![BU of 5kar by Molmil](/molmil-images/mine/5kar) | Murine acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3b, ... | 著者 | Gorelik, A, Illes, K, Heinz, L.X, Superti-Furga, G, Nagar, B. | 登録日 | 2016-06-02 | 公開日 | 2016-10-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.142 Å) | 主引用文献 | Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. J.Biol.Chem., 291, 2016
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7M41
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![BU of 7m41 by Molmil](/molmil-images/mine/7m41) | Structure of TIM-3 in complex with N-(4-(8-chloro-2-methyl-5-oxo-5,6-dihydro-[1,2,4]traizolo[1,5-c]quinazolin-9-yl)-3-methylphenyl)-1H-imidazole-2-sulfonamide (compound 38) | 分子名称: | CALCIUM ION, Hepatitis A virus cellular receptor 2, N-{4-[(4S,10aP)-8-chloro-2-methyl-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]quinazolin-9-yl]-3-methylphenyl}-1H-imidazole-2-sulfonamide | 著者 | Rietz, T.A. | 登録日 | 2021-03-19 | 公開日 | 2021-10-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3). J.Med.Chem., 64, 2021
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6I37
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![BU of 6i37 by Molmil](/molmil-images/mine/6i37) | Crystal structure of nv1Pizza6-AYW, a circularly permuted designer protein | 分子名称: | SULFATE ION, nv1Pizza6-AYW | 著者 | Mylemans, B, Noguchi, H, Deridder, E, Voet, A.R.D. | 登録日 | 2018-11-05 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Influence of circular permutations on the structure and stability of a six-fold circular symmetric designer protein. Protein Sci., 2020
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5KB0
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![BU of 5kb0 by Molmil](/molmil-images/mine/5kb0) | Crystal Structure of a Tris-thiolate Pb(II) Complex in a de Novo Three-stranded Coiled Coil Peptide | 分子名称: | CHLORIDE ION, LEAD (II) ION, Pb(II)Zn(II)(GRAND Coil Ser-L16CL30H)3+, ... | 著者 | Ruckthong, L, Zastrow, M.L, Stuckey, J.A, Pecoraro, V.L. | 登録日 | 2016-06-02 | 公開日 | 2016-08-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | A Crystallographic Examination of Predisposition versus Preorganization in de Novo Designed Metalloproteins. J.Am.Chem.Soc., 138, 2016
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6I3H
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![BU of 6i3h by Molmil](/molmil-images/mine/6i3h) | Crystal structure of influenza A virus M1 N-terminal domain (G18A mutation) | 分子名称: | Matrix protein 1, PHOSPHATE ION | 著者 | Miyake, Y, Keusch, J.J, Decamps, L, Ho-Xuan, H, Iketani, S, Gut, H, Kutay, U, Helenius, A, Yamauchi, Y. | 登録日 | 2018-11-06 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Influenza virus uses transportin 1 for vRNP debundling during cell entry. Nat Microbiol, 4, 2019
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