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PDB: 88675 件

5JKN
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Crystal structure of deubiquitinase MINDY-1
分子名称: DI(HYDROXYETHYL)ETHER, MERCURY (II) ION, PHOSPHATE ION, ...
著者Abdul Rehman, S.A, Kulathu, Y.
登録日2016-04-26
公開日2016-06-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes.
Mol.Cell, 63, 2016
6OUJ
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Carbonic Anhydrase II complexed with benzene sulfonamide MB11-689A
分子名称: 3-[(1S)-1-(4-nitrophenyl)ethyl]-2-oxo-2,3-dihydro-1,3-benzoxazole-5-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Kota, A, McKenna, R.
登録日2019-05-04
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.466 Å)
主引用文献Carbonic Anhydrase II complexed with benzene sulfonamide MB11-689A
To Be Published
8SNZ
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X-ray Crystal Structure of FMN-bound long-chain flavodoxin from Rhodopseudomonas palustris
分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin
著者Ansari, A, Khan, S.A, Miller, A.F.
登録日2023-04-28
公開日2024-03-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure, dynamics, and redox reactivity of an all-purpose flavodoxin.
J.Biol.Chem., 300, 2024
6EW7
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BU of 6ew7 by Molmil
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
分子名称: 2-chloranyl-4-[[5-chloranyl-4-[(4-fluorophenyl)amino]pyrimidin-2-yl]amino]benzoic acid, B-cell lymphoma 6 protein, CHLORIDE ION
著者Robb, G, Ferguson, A, Hargreaves, D.
登録日2017-11-03
公開日2018-10-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
7SHJ
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BU of 7shj by Molmil
Crystal structure of Acinetobacter baumannii ZnuA in the metal-free state
分子名称: SODIUM ION, Zinc ABC transporter solute-binding protein
著者Luo, Z, McDevitt, C.A, Kobe, B.
登録日2021-10-09
公開日2022-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural and biochemical characterization of Acinetobacter baumannii ZnuA.
J.Inorg.Biochem., 231, 2022
6EVD
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BU of 6evd by Molmil
Structure of R173A A. niger Fdc1 with prFMN in the hydroxylated form
分子名称: Ferulic acid decarboxylase 1, MANGANESE (II) ION, POTASSIUM ION, ...
著者Bailey, S.S, David, L, Payne, K.A.P.
登録日2017-11-01
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis.
J. Biol. Chem., 293, 2018
8SLV
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BU of 8slv by Molmil
Structure of a salivary alpha-glucosidase from the mosquito vector Aedes aegypti.
分子名称: 1,3-PROPANDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gittis, A.G, Williams, A.E, Garboczi, D, Calvo, E.
登録日2023-04-24
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural and functional comparisons of salivary alpha-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus.
Insect Biochem.Mol.Biol., 167, 2024
5MHU
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BU of 5mhu by Molmil
The study of the X-ray induced enzymatic reduction of molecular oxygen to water for laccase from Steccherinum murashkinskyi.The third structure of the series with total exposition time 63 min.
分子名称: CITRIC ACID, COPPER (II) ION, Laccase 2, ...
著者Polyakov, K.M, Gavryushov, S, Fedorova, T.V, Glazunova, O.A, Popov, A.N.
登録日2016-11-25
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural study of the X-ray-induced enzymatic reduction of molecular oxygen to water by Steccherinum murashkinskyi laccase: insights into the reaction mechanism.
Acta Crystallogr D Struct Biol, 73, 2017
5MI1
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The study of the X-ray induced enzymatic reduction of molecular oxygen to water for laccase from Steccherinum murashkinskyi.The 9-th structure of the series with total exposition time 243 min.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, COPPER (II) ION, ...
著者Polyakov, K.M, Gavryushov, S, Fedorova, T.V, Glazunova, O.A, Popov, A.N.
登録日2016-11-27
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural study of the X-ray-induced enzymatic reduction of molecular oxygen to water by Steccherinum murashkinskyi laccase: insights into the reaction mechanism.
Acta Crystallogr D Struct Biol, 73, 2017
5MIB
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BU of 5mib by Molmil
The study of the X-ray induced enzymatic reduction of molecular oxygen to water for laccase from Steccherinum murashkinskyi.The 12-th structure of the series with total exposition time 333 min.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, COPPER (II) ION, ...
著者Polyakov, K.M, Gavryushov, S, Fedorova, T.V, Glazunova, O.A, Popov, A.N.
登録日2016-11-28
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural study of the X-ray-induced enzymatic reduction of molecular oxygen to water by Steccherinum murashkinskyi laccase: insights into the reaction mechanism.
Acta Crystallogr D Struct Biol, 73, 2017
6RTE
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BU of 6rte by Molmil
Dihydro-heme d1 dehydrogenase NirN in complex with DHE
分子名称: (R,R)-2,3-BUTANEDIOL, Cytochrome c, HEME C
著者Kluenemann, T, Preuss, A, Layer, G, Blankenfeldt, W.
登録日2019-05-23
公開日2019-06-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structure of Dihydro-Heme d1Dehydrogenase NirN from Pseudomonas aeruginosa Reveals Amino Acid Residues Essential for Catalysis.
J.Mol.Biol., 431, 2019
6VGY
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BU of 6vgy by Molmil
2.05 A resolution structure of MERS 3CL protease in complex with inhibitor 6b
分子名称: N~2~-{[(trans-4-ethylcyclohexyl)oxy]carbonyl}-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide, Orf1a protein
著者Lovell, S, Battaile, K.P, Kashipathy, M.M, Rathnayake, A.D, Zheng, J, Kim, Y, Nguyen, H.N, Chang, K.O, Groutas, W.C.
登録日2020-01-09
公開日2020-08-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice.
Sci Transl Med, 12, 2020
5J8D
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BU of 5j8d by Molmil
Structure of nitroreductase from E. cloacae complexed with nicotinic acid adenine dinucleotide
分子名称: FLAVIN MONONUCLEOTIDE, NICOTINIC ACID ADENINE DINUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase
著者Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W.
登録日2016-04-07
公開日2017-05-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase.
Structure, 25, 2017
4XMT
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BU of 4xmt by Molmil
Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid
分子名称: Aminopeptidase N, DIAMINOPROPANOIC ACID, GLYCEROL, ...
著者Addlagatta, A, Gumpena, R.
登録日2015-01-15
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid
To Be Published
6OTO
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BU of 6oto by Molmil
Carbonic Anhydrase II complexed with ureic benzene sulfonamide MB9-561B
分子名称: 4-hydroxy-3-({[(pyridin-4-yl)methyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Kota, A, McKenna, R.
登録日2019-05-03
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.496 Å)
主引用文献Carbonic Anhydrase II complexed with ureido benzene sulfonamide MB9-561B
To Be Published
8CDK
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BU of 8cdk by Molmil
CAND1 b-hairpin++-SCF-SKP2 CAND1 partly engaged SCF partly rocked
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2023-01-31
公開日2023-04-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
6RVY
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BU of 6rvy by Molmil
Inward-open structure of the ASCT2 (SLC1A5) mutant C467R in absence of substrate
分子名称: Neutral amino acid transporter B(0)
著者Garaeva, A.A, Guskov, A, Slotboom, D.J, Paulino, C.
登録日2019-06-03
公開日2019-08-07
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.13 Å)
主引用文献A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2.
Nat Commun, 10, 2019
5MME
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BU of 5mme by Molmil
Crystal structure of CREBBP bromodomain complexd with US46C
分子名称: CREB-binding protein, dimethyl 5-[(5-ethanoyl-2-ethoxy-phenyl)amino]benzene-1,3-dicarboxylate
著者Zhu, J, Caflisch, A.
登録日2016-12-09
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6EZI
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BU of 6ezi by Molmil
PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.
分子名称: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2
著者Loew, C, Flayhan, A, Pieprzyk, J.
登録日2017-11-15
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.503321 Å)
主引用文献Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution.
Structure, 26, 2018
5IUS
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BU of 5ius by Molmil
Crystal structure of human PD-L1 in complex with high affinity PD-1 mutant
分子名称: CHLORIDE ION, Programmed cell death 1 ligand 1, Programmed cell death protein 1
著者Pascolutti, R, Sun, X, Kao, J, Maute, R, Ring, A.M, Bowman, G.R, Kruse, A.C.
登録日2016-03-18
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.889 Å)
主引用文献Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
Structure, 24, 2016
8CI7
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BU of 8ci7 by Molmil
Apo-crystal structure of a wild-type South African HIV-1 subtype C protease at 2.4 angstrom
分子名称: Truncated pol polyprotein
著者Dlamini, N.P, Pandian, R, Onisuru, O, Achilonu, I.A, Sayed, Y.
登録日2023-02-09
公開日2023-04-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Biophysical and biochemical characterization of a wild-type South African HIV-1 subtype C protease
To Be Published
8CDJ
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BU of 8cdj by Molmil
CAND1 b-hairpin++-SCF-SKP2 CAND1 rolling SCF engaged
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2023-01-31
公開日2023-04-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
5MMZ
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BU of 5mmz by Molmil
Structure of PRL-1 in complex with the Bateman domain of CNNM2
分子名称: Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1
著者Gimenez-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-Orbea, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M.L, Martinez-Cruz, L.A.
登録日2016-12-12
公開日2016-12-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
7AQV
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BU of 7aqv by Molmil
Flavin-dependent tryptophan halogenase Thal: N-terminally His-tagged form of quintuple mutant (NHis-Thal-RebH5)
分子名称: GLYCEROL, Tryptophan 6-halogenase
著者Moritzer, A.C, Prior, T, Niemann, H.H.
登録日2020-10-23
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Not Cleaving the His-tag of Thal Results in More Tightly Packed and Better-Diffracting Crystals
Crystals, 2020
4XO3
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BU of 4xo3 by Molmil
Crystal Structure of E. coli Aminopeptidase N in complex with L-Leucine
分子名称: Aminopeptidase N, GLYCEROL, LEUCINE, ...
著者Addlagatta, A, Gumpena, R.
登録日2015-01-16
公開日2016-01-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of E. coli Aminopeptidase N in complex with L-Leucine
To Be Published

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件を2024-07-31に公開中

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