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PDB: 89346 件

5MGJ
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Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridine derivative 1
分子名称: Bromodomain adjacent to zinc finger domain protein 2A, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate
著者Lolli, G, Spiliotopoulos, D, Caflisch, A.
登録日2016-11-21
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of BAZ2A bromodomain ligands.
Eur J Med Chem, 139, 2017
6SEH
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BU of 6seh by Molmil
Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease
分子名称: Structure-specific endonuclease subunit SLX1, Structure-specific endonuclease subunit SLX4, ZINC ION
著者Gaur, V, Zajko, W, Nirwal, S, Szlachcic, A, Gapinska, M, Nowotny, M.
登録日2019-07-30
公開日2019-09-25
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.
Nucleic Acids Res., 47, 2019
5JUV
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BU of 5juv by Molmil
STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-b-Galactopyranosyl galactose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, PENTAETHYLENE GLYCOL, ...
著者Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J.
登録日2016-05-10
公開日2017-04-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages.
FEBS J., 284, 2017
6SAB
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BU of 6sab by Molmil
M-BUTX-Ptr1a (Parabuthus transvaalicus)
分子名称: M-BUTX-Ptr1a
著者Meudal, H, Landon, C, Delmas, A.F.
登録日2019-07-16
公開日2020-07-22
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
J.Med.Chem., 63, 2020
6SEU
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BU of 6seu by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 21h exposure of protein crystals to compound 2
分子名称: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
著者Ferraro, G, Giorgio, A, Merlino, A.
登録日2019-07-30
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
8RB7
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BU of 8rb7 by Molmil
Structure of the two-fold capsomer of the PNMA2 capsid
分子名称: Paraneoplastic antigen Ma2 homolog
著者Erlendsson, S, Xu, J, Shepherd, J.D, Briggs, J.A.G.
登録日2023-12-03
公開日2024-02-14
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome.
Cell, 187, 2024
8GLX
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BU of 8glx by Molmil
CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
著者Shen, Y, Guarne, A.
登録日2023-03-23
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
4QX1
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BU of 4qx1 by Molmil
Cry3A Toxin structure obtained by Serial Femtosecond Crystallography from in vivo grown crystals isolated from Bacillus thuringiensis and data processed with the CrystFEL software suite
分子名称: Pesticidal crystal protein cry3Aa
著者Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D.
登録日2014-07-17
公開日2014-08-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
6SG8
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BU of 6sg8 by Molmil
Structure of Sosuga virus receptor binding protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
著者Bowden, T.A, Stelfox, A.J.
登録日2019-08-02
公開日2019-10-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A structure-based rationale for sialic acid independent host-cell entry of Sosuga virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
6ME7
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BU of 6me7 by Molmil
XFEL crystal structure of human melatonin receptor MT2 (H208A) in complex with 2-phenylmelatonin
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide, Soluble cytochrome b562,Melatonin receptor type 1B,Rubredoxin, ...
著者Johansson, L.C, Stauch, B, McCorvy, J, Han, G.W, Patel, N, Batyuk, A, Gati, C, Li, C, Grandner, J, Hao, S, Olsen, R.H.J, Tribo, A.R, Zaare, S, Zhu, L, Zatsepin, N.A, Weierstall, U, Liu, W, Roth, B.L, Katritch, V, Cherezov, V.
登録日2018-09-05
公開日2019-04-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献XFEL structures of the human MT2melatonin receptor reveal the basis of subtype selectivity.
Nature, 569, 2019
6S9M
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BU of 6s9m by Molmil
Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKITW, ...
著者Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A.
登録日2019-07-15
公開日2020-02-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
8E8W
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BU of 8e8w by Molmil
Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 mononuclear Fe(II) structure on the HDO cofactor assembly pathway
分子名称: Cupin domain-containing diiron protein, FE (II) ION
著者McBride, M.J, Boal, A.K.
登録日2022-08-25
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 mononuclear Fe(II) structure on the HDO cofactor assembly pathway
To Be Published
8GLW
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BU of 8glw by Molmil
CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
著者Shen, Y, Guarne, A.
登録日2023-03-23
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
8BDJ
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BU of 8bdj by Molmil
VCB in complex with compound 30
分子名称: (2~{S},4~{R})-~{N}-[(1~{S})-1-[4-chloranyl-2-(2-methoxyethoxy)phenyl]ethyl]-1-[(2~{R})-3-methyl-2-(3-methyl-1,2-oxazol-5-yl)butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ...
著者Sorrell, F.J, Mueller, J.E, Lehmann, M, Wegener, A.
登録日2022-10-19
公開日2023-02-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design.
Chemmedchem, 18, 2023
5MHV
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BU of 5mhv by Molmil
The study of the X-ray induced enzymatic reduction of molecular oxygen to water for laccase from Steccherinum murashkinskyi.The fourth structure of the series with total exposition time 93 min.
分子名称: CITRIC ACID, COPPER (II) ION, Laccase 2, ...
著者Polyakov, K.M, Gavryushov, S, Fedorova, T.V, Glazunova, O.A, Popov, A.N.
登録日2016-11-25
公開日2017-05-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural study of the X-ray-induced enzymatic reduction of molecular oxygen to water by Steccherinum murashkinskyi laccase: insights into the reaction mechanism.
Acta Crystallogr D Struct Biol, 73, 2017
5G2W
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BU of 5g2w by Molmil
S. enterica HisA mutant D10G, G102A
分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SULFATE ION
著者Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M.
登録日2016-04-14
公開日2017-04-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8GDT
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BU of 8gdt by Molmil
Heligmosomoides polygyrus TGF-beta Mimic 6 Domain 3 (TGM6-D3) Bound to Human TGF-beta Type II Receptor Extracellular Domain
分子名称: CACODYLATE ION, CHLORIDE ION, GLYCEROL, ...
著者White, S.E, Schwartze, T.A, Hinck, A.P.
登録日2023-03-06
公開日2024-09-11
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Heligmosomoides polygyrus TGF-beta Mimic 6 Domain 3 (TGM6-D3) Bound to Human TGF-beta Type II Receptor Extracellular Domain
To Be Published
6YRY
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BU of 6yry by Molmil
tRNA-Guanine Transglycosylase (TGT) H333A mutant crystallised at pH 5.5
分子名称: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION
著者Nguyen, A, Heine, A, Klebe, G.
登録日2020-04-20
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Mutation study on tRNA-guanine transglycosylase for catalysis testing
To Be Published
4QSR
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BU of 4qsr by Molmil
Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound MPD
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATPase family AAA domain-containing protein 2, GLYCEROL, ...
著者Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2014-07-06
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based approaches towards identification of fragments for the low-druggability ATAD2 bromodomain
MedChemComm, 5, 2014
5MI2
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BU of 5mi2 by Molmil
The study of the X-ray induced enzymatic reduction of molecular oxygen to water for laccase from Steccherinum murashkinskyi.The 10-th structure of the series with total exposition time 273 min.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, COPPER (II) ION, ...
著者Polyakov, K.M, Gavryushov, S, Fedorova, T.V, Glazunova, O.A, Popov, A.N.
登録日2016-11-27
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural study of the X-ray-induced enzymatic reduction of molecular oxygen to water by Steccherinum murashkinskyi laccase: insights into the reaction mechanism.
Acta Crystallogr D Struct Biol, 73, 2017
5MIC
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BU of 5mic by Molmil
The study of the X-ray induced enzymatic reduction of molecular oxygen to water for laccase from Steccherinum murashkinskyi.The 13-th structure of the series with total exposition time 363 min.
分子名称: CITRIC ACID, COPPER (II) ION, Laccase 2, ...
著者Polyakov, K.M, Gavryushov, S, Fedorova, T.V, Glazunova, O.A, Popov, A.N.
登録日2016-11-28
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural study of the X-ray-induced enzymatic reduction of molecular oxygen to water by Steccherinum murashkinskyi laccase: insights into the reaction mechanism.
Acta Crystallogr D Struct Biol, 73, 2017
6MFE
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BU of 6mfe by Molmil
Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000773 (Compound 11g) Complex
分子名称: (2-nitro-4-{[(3S)-1-{[4-(trifluoromethoxy)phenyl]methyl}pyrrolidin-3-yl]amino}phenyl)methanol, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein
著者Taylor, A.B.
登録日2018-09-10
公開日2018-10-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.444 Å)
主引用文献Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.
ACS Med Chem Lett, 9, 2018
7Z2Y
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BU of 7z2y by Molmil
Escherichia coli periplasmic phytase AppA T305E mutant, complex with myo-inositol hexakissulfate
分子名称: Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, NICKEL (II) ION
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-03-01
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
7MW1
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BU of 7mw1 by Molmil
Crystal structure of the Homo sapiens NUP93-NUP53 complex (NUP93 residues 174-819; NUP53 residues 84-150)
分子名称: Nuclear pore complex protein Nup93, Nucleoporin Nup35
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-05-15
公開日2022-06-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
5MHX
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BU of 5mhx by Molmil
The study of the X-ray induced enzymatic reduction of molecular oxygen to water for laccase from Steccherinum murashkinskyi.The sixth structure of the series with total exposition time 153 min.
分子名称: CITRIC ACID, COPPER (II) ION, Laccase 2, ...
著者Polyakov, K.M, Gavryushov, S, Fedorova, T.V, Glazunova, O.A, Popov, A.N.
登録日2016-11-26
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural study of the X-ray-induced enzymatic reduction of molecular oxygen to water by Steccherinum murashkinskyi laccase: insights into the reaction mechanism.
Acta Crystallogr D Struct Biol, 73, 2017

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