8WNP
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9FWC
| Coxsackievirus B3 3C protease in C121 spacegroup | 分子名称: | Genome polyprotein | 著者 | Fairhead, M, Lithgo, R.M, MacLean, E.M, Bowesman-Jones, H, Aschenbrenner, J.C, Balcomb, B.H, Capkin, E, Chandran, A.V, Godoy, A.S, Marples, P.G, Fearon, D, von Delft, F, Koekemoer, L. | 登録日 | 2024-06-28 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Coxsackievirus B3 3C protease in C121 spacegroup To Be Published
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8BF8
| ISDra2 TnpB in complex with reRNA | 分子名称: | Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB | 著者 | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D. | 登録日 | 2022-10-24 | 公開日 | 2023-04-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | TnpB structure reveals minimal functional core of Cas12 nuclease family. Nature, 616, 2023
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9CJA
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6OAU
| Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in GnTI-deficient HEK293-F cells | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, ... | 著者 | Arora, R, Horton, P.A, Benson, T.E, Romanowski, M.J. | 登録日 | 2019-03-18 | 公開日 | 2019-05-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structure of lipoprotein lipase in complex with GPIHBP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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8WOP
| Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, wild-type | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase 2, URIDINE-5'-DIPHOSPHATE | 著者 | Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S. | 登録日 | 2023-10-07 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis. Plant J., 119, 2024
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7MVS
| DNA gyrase complexed with uncleaved DNA and Compound 7 to 2.6A resolution | 分子名称: | (1S)-2-[(2r,5S)-5-{[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]amino}-1,3-dioxan-2-yl]-1-(3-fluoro-6-methoxyquinolin-4-yl)ethan-1-ol, CHLORIDE ION, DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... | 著者 | Ratigan, S.C, McElroy, C.A. | 登録日 | 2021-05-15 | 公開日 | 2021-10-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.60137153 Å) | 主引用文献 | Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA. J.Med.Chem., 64, 2021
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8YRV
| Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis complexed with 3-aminooxypropionic acid | 分子名称: | 3-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]oxypropanoic acid, Aminotransferase class IV, MAGNESIUM ION | 著者 | Matyuta, I.O, Bakunova, A.K, Nikolaeva, A.Y, Popov, V.O, Boyko, K.M. | 登録日 | 2024-03-21 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis complexed with 3-aminooxypropionic acid To Be Published
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6OB0
| Compound 2 bound structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Arora, R, Horton, P.A, Benson, T.E, Romanowski, M.J. | 登録日 | 2019-03-19 | 公開日 | 2019-05-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structure of lipoprotein lipase in complex with GPIHBP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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9BJ0
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9CLY
| Crystal structure of the 3-ketoacyl-(acyl-carrier-protein) reductase, CylG, from Streptococcus agalactiae 2603V/R | 分子名称: | CylG protein, IMIDAZOLE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Maltseva, N, Kim, Y, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2024-07-12 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure of the 3-ketoacyl-(acyl-carrier-protein) reductase, CylG, from Streptococcus agalactiae 2603V/R To be published
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8WNU
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9CBE
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8ZM1
| Structure of human pyruvate dehydrogenase kinase 2 complexed with compound 6 | 分子名称: | (5~{R})-5-propan-2-ylindeno[1,2-b]pyridin-5-ol, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 著者 | Akai, S, Orita, T, Nomura, A, Adachi, T. | 登録日 | 2024-05-22 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Design and synthesis of novel fluorene derivatives as inhibitors of pyruvate dehydrogenase kinase. Bioorg.Med.Chem.Lett., 109, 2024
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7M78
| Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J. | 登録日 | 2021-03-26 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I. Sci Rep, 11, 2021
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8WO4
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7OW8
| CryoEM structure of the ABC transporter BmrA E504A mutant in complex with ATP-Mg | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | 著者 | Gobet, A, Schoehn, G, Falson, P, Chaptal, V. | 登録日 | 2021-06-17 | 公開日 | 2022-01-19 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
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8EDP
| Crystal structure of a three-tetrad, parallel, and K+ stabilized homopurine G-quadruplex from human chromosome 7 | 分子名称: | COBALT HEXAMMINE(III), DNA (5'-D(*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*G)-3'), N-METHYLMESOPORPHYRIN, ... | 著者 | Ye, M, Yatsunyk, L.A. | 登録日 | 2022-09-05 | 公開日 | 2022-12-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad. Bioorg.Med.Chem., 77, 2022
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7M75
| Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J. | 登録日 | 2021-03-26 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I. Sci Rep, 11, 2021
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7M76
| Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J. | 登録日 | 2021-03-26 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I. Sci Rep, 11, 2021
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9FAA
| Cryo-EM structure of cardiac collagen-associated amyloid AL59 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | 著者 | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | 登録日 | 2024-05-10 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis Nature Communications, 2024
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6WLR
| SAM-IV riboswitch with SAM models, 4.8 Angstrom resolution | 分子名称: | RNA (119-MER) | 著者 | Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R. | 登録日 | 2020-04-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nat.Methods, 17, 2020
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8DV6
| Zika virus envelope protein structure in complex with a potent Human mAb | 分子名称: | Envelope protein E, mAb Fab Heavy Chain, mAb Fab Light Chain | 著者 | Cameron, A, Puhl, A.C, deSilva, A.M, Premkumar, L. | 登録日 | 2022-07-28 | 公開日 | 2023-01-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus. Plos Pathog., 19, 2023
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7P3R
| Helical structure of the toxin MakA from Vibrio cholera | 分子名称: | MakA tetramer | 著者 | Berg, A, Nadeem, A, Uhlin, B.E, Wai, S.N, Barandun, J. | 登録日 | 2021-07-08 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae . Elife, 11, 2022
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6ZT3
| N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit complexed with ADPNP | 分子名称: | 1,2-ETHANEDIOL, DNA gyrase subunit B, MAGNESIUM ION, ... | 著者 | Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A. | 登録日 | 2020-07-17 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic. Proc.Natl.Acad.Sci.USA, 118, 2021
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