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Triazolopyridine-based Inhibitor of Janus Kinase 2
Descriptor:	8-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine, SULFATE ION, TYROSINE-PROTEIN KINASE JAK2
Authors:	Dugan, B.J, Gingrich, D.E, Mesaros, E.F, Milkiewicz, K.L, Curry, M.A, Zulli, A.L, Dobrzanski, P, Serdikoff, C, Jan, M, Angeles, T.S, Albom, M.S, Mason, J.L, Aimone, L.D, Meyer, S.L, Huang, Z, Wells-Knecht, K.J, Ator, M.A, Ruggeri, B.A, Dorsey, B.D.
Deposit date:	2012-04-16
Release date:	2012-04-25
Last modified:	2019-05-08
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-A]Pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of Cep-33779. J.Med.Chem., 55, 2012

Crystal Structure of Human Coagulation Factor XA Complexed with FXV673
Descriptor:	CALCIUM ION, COAGULATION FACTOR XA, METHYL-3-(4'-N-OXOPYRIDYLPHENOYL)-3-METHYL-2-(M-AMIDINOBENZYL)-PROPIONATE
Authors:	Maignan, S, Guilloteau, J.P.
Deposit date:	2002-01-14
Release date:	2002-06-19
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Optimization of the beta-aminoester class of factor Xa inhibitors. Part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity. Bioorg.Med.Chem.Lett., 12, 2002