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9BH8
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BU of 9bh8 by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BHA
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BU of 9bha by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH9
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BU of 9bh9 by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH7
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BU of 9bh7 by Molmil
Human DNA polymerase theta helicase domain dimer in the apo form
Descriptor: DNA polymerase theta
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH6
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BU of 9bh6 by Molmil
Human DNA polymerase theta helicase domain tetramer in the apo form
Descriptor: DNA polymerase theta
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
7R8R
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BU of 7r8r by Molmil
Physachenolide C with Bromodomain (BRD3-BD1)
Descriptor: Bromodomain-containing protein 3, Physachenolide C
Authors:Fromme, R, Sivinski, J, Zerio, C, Gunatilaka, A.A.L, Chapman, E.
Deposit date:2021-06-27
Release date:2022-09-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Physachenolide C is a Potent, Selective BET Inhibitor.
J.Med.Chem., 66, 2023
7S3P
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BU of 7s3p by Molmil
BD2 domain of human BRD3 bound to Physachenolide C
Descriptor: Bromodomain-containing protein 3, CHLORIDE ION, Physachenolide C
Authors:Horton, N.C, Chapman, E, Sivinski, J, Zerio, C, Ghadirian, N.
Deposit date:2021-09-07
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Physachenolide C is a Potent, Selective BET Inhibitor.
J.Med.Chem., 66, 2023

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PDB entries from 2024-07-03

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