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Crystal structure of SRPK1 in complex with a peptide inhibitor
Descriptor:	ARG-GLU-ARG-ALA-ARG-THR-ARG, SRSF protein kinase 1,SRSF protein kinase 1
Authors:	Li, Q.Y, Yung, K.W.Y, Ngo, J.C.K.
Deposit date:	2020-10-27
Release date:	2021-04-21
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Protein-Protein Interaction Inhibitor of SRPKs Alters the Splicing Isoforms of VEGF and Inhibits Angiogenesis. Iscience, 24, 2021

Crystal Structure of the GULP1 PTB domain-APP peptide complex
Descriptor:	1,2-ETHANEDIOL, Amyloid beta A4 protein, PTB domain-containing engulfment adapter protein 1, ...
Authors:	Yung, K.W.Y, Lau, K.F, Ngo, J.C.K.
Deposit date:	2018-11-26
Release date:	2019-08-14
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2.17 Å)
Cite:	Attenuation of amyloid-beta generation by atypical protein kinase C-mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35. Faseb J., 33, 2019

Crystal structure of uPA in complex with a camelid-derived antibody fragment
Descriptor:	(3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL LAURATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Camelid Derived Antibody Fragment, ...
Authors:	Yung, K.W.Y, Kromann-Hansen, T, Andreasen, P.A, Ngo, J.C.K.
Deposit date:	2016-01-08
Release date:	2016-06-01
Last modified:	2016-08-10
Method:	X-RAY DIFFRACTION (1.97 Å)
Cite:	A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior J.Biol.Chem., 291, 2016