8IFJ
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3VQV
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![BU of 3vqv by Molmil](/molmil-images/mine/3vqv) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AMPPNP (re-refined) | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase | Authors: | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2012-04-01 | Release date: | 2013-01-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site Acta Crystallogr.,Sect.D, 69, 2013
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3VQX
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![BU of 3vqx by Molmil](/molmil-images/mine/3vqx) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in triclinic crystal form | Descriptor: | ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Pyrrolysine--tRNA ligase, ... | Authors: | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2012-04-02 | Release date: | 2013-01-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site Acta Crystallogr.,Sect.D, 69, 2013
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3VQW
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![BU of 3vqw by Molmil](/molmil-images/mine/3vqw) | Crystal structure of the SeMet substituted catalytic domain of pyrrolysyl-tRNA synthetase | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase | Authors: | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2012-04-01 | Release date: | 2013-01-02 | Last modified: | 2013-09-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site Acta Crystallogr.,Sect.D, 69, 2013
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3VQY
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![BU of 3vqy by Molmil](/molmil-images/mine/3vqy) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and AMPPNP (form 2) | Descriptor: | MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2012-04-02 | Release date: | 2013-01-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site Acta Crystallogr.,Sect.D, 69, 2013
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6AAZ
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![BU of 6aaz by Molmil](/molmil-images/mine/6aaz) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pNO2ZLys | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-19 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.842 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AB8
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![BU of 6ab8 by Molmil](/molmil-images/mine/6ab8) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZLys | Descriptor: | (2S)-2-azanyl-6-(phenylmethoxycarbonylamino)hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-20 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.753 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AB2
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![BU of 6ab2 by Molmil](/molmil-images/mine/6ab2) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oClZLys | Descriptor: | (2S)-2-azanyl-6-[(2-chlorophenyl)methoxycarbonylamino]hexanoic acid, 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-19 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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3WNC
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![BU of 3wnc by Molmil](/molmil-images/mine/3wnc) | Crystal structure of EF-Pyl in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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3WNB
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![BU of 3wnb by Molmil](/molmil-images/mine/3wnb) | Crystal structure of EF-Pyl in complex with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2020-05-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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3WND
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![BU of 3wnd by Molmil](/molmil-images/mine/3wnd) | Crystal structure of EF-Pyl | Descriptor: | CITRIC ACID, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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2EL7
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![BU of 2el7 by Molmil](/molmil-images/mine/2el7) | Crystal structure of Tryptophanyl-tRNA synthetase from Thermus thermophilus | Descriptor: | PHOSPHATE ION, Tryptophanyl-tRNA synthetase | Authors: | Yanagisawa, T, Sumida, T, Ishii, R, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-26 | Release date: | 2008-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Tryptophanyl-tRNA synthetase from Thermus thermophilus To be published
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2E3C
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2ZIN
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![BU of 2zin by Molmil](/molmil-images/mine/2zin) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and an ATP analogue | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, ... | Authors: | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-02-19 | Release date: | 2008-12-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification Chem.Biol., 15, 2008
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2ZCE
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![BU of 2zce by Molmil](/molmil-images/mine/2zce) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with pyrrolysine and an ATP analogue | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PYRROLYSINE, ... | Authors: | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-11-08 | Release date: | 2008-04-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase J.Mol.Biol., 378, 2008
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2ZIO
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![BU of 2zio by Molmil](/molmil-images/mine/2zio) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AlocLys-AMP and PNP | Descriptor: | 5'-O-[(S)-({(2S)-2-amino-6-[(propoxycarbonyl)amino]hexanoyl}oxy)(hydroxy)phosphoryl]adenosine, IMIDODIPHOSPHORIC ACID, Pyrrolysyl-tRNA synthetase | Authors: | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-02-19 | Release date: | 2008-12-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification Chem.Biol., 15, 2008
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2EL9
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![BU of 2el9 by Molmil](/molmil-images/mine/2el9) | Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue | Descriptor: | 5'-O-[(L-HISTIDYLAMINO)SULFONYL]ADENOSINE, Histidyl-tRNA synthetase | Authors: | Yanagisawa, T, Si, S.Y, Matsuno, M, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-27 | Release date: | 2008-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue To be published
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6ABK
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![BU of 6abk by Molmil](/molmil-images/mine/6abk) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TeocLys | Descriptor: | (2S)-2-azanyl-6-(trimethylsilylmethoxycarbonylamino)hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-22 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AAO
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![BU of 6aao by Molmil](/molmil-images/mine/6aao) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-18 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.403 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AB0
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![BU of 6ab0 by Molmil](/molmil-images/mine/6ab0) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pAmPyLys | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-{[(6-aminopyridin-3-yl)methoxy]carbonyl}-L-lysine, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-19 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.441 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AAP
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![BU of 6aap by Molmil](/molmil-images/mine/6aap) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZaeSeCys | Descriptor: | 3-[(2-{[(benzyloxy)carbonyl]amino}ethyl)selanyl]-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-18 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AAD
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![BU of 6aad by Molmil](/molmil-images/mine/6aad) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mTmdZLys | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-[({3-[3-(trifluoromethyl)-3H-diaziren-3-yl]phenyl}methoxy)carbonyl]-L-lysine, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-18 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.444 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AAQ
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![BU of 6aaq by Molmil](/molmil-images/mine/6aaq) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with BCNLys | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-({[(1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)-L-lysine, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-18 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.551 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AAN
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![BU of 6aan by Molmil](/molmil-images/mine/6aan) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mEtZLys | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-18 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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6AAC
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![BU of 6aac by Molmil](/molmil-images/mine/6aac) | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Yanagisawa, T, Kuratani, M, Yokoyama, S. | Deposit date: | 2018-07-18 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.479 Å) | Cite: | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019
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