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3NBK
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BU of 3nbk by Molmil
Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine
Descriptor: 4'-PHOSPHOPANTETHEINE, NICKEL (II) ION, Phosphopantetheine adenylyltransferase
Authors:Wubben, T.J, Mesecar, A.D.
Deposit date:2010-06-03
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis.
J.Mol.Biol., 404, 2010
3NBA
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BU of 3nba by Molmil
Phosphopantetheine Adenylyltranferase from Mycobacterium tuberculosis in complex with adenosine-5'-[(alpha,beta)-methyleno]triphosphate (AMPCPP)
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, Phosphopantetheine adenylyltransferase
Authors:Wubben, T.J, Mesecar, A.D.
Deposit date:2010-06-03
Release date:2010-09-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis.
J.Mol.Biol., 404, 2010
8G2E
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BU of 8g2e by Molmil
PKM2 bound to compound 2
Descriptor: 1,2-ETHANEDIOL, 3-[(3-aminophenyl)methyl]-5-methyl-7-[methyl(oxidanyl)-$l^{3}-sulfanyl]pyridazino[4,5-b]indol-4-one, MAGNESIUM ION, ...
Authors:Stuckey, J.A.
Deposit date:2023-02-03
Release date:2023-05-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.838 Å)
Cite:Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis.
Pharmaceuticals, 16, 2023
3PNB
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BU of 3pnb by Molmil
Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A
Descriptor: COENZYME A, Phosphopantetheine adenylyltransferase
Authors:Wubben, T.J, Mesecar, A.D.
Deposit date:2010-11-18
Release date:2011-06-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structure of Mycobacterium tuberculosisphosphopantetheine adenylyltransferase in complex with the feedback inhibitor CoA reveals only one active-site conformation.
Acta Crystallogr.,Sect.F, 67, 2011

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