6A7B
| AKR1C3 complexed with new inhibitor with novel scaffold | Descriptor: | (4R)-6-amino-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-3-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, Aldo-keto reductase family 1 member C3, DIMETHYLFORMAMIDE, ... | Authors: | Zheng, X, Zhao, Y, Zhang, H, Chen, Y. | Deposit date: | 2018-07-02 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors. Bioorg.Med.Chem., 26, 2018
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5OID
| Complex Trichoplax STIL-NTD:human CEP85 coiled coil domain 4 | Descriptor: | Centrosomal protein of 85 kDa, Putative uncharacterized protein | Authors: | van Breugel, M. | Deposit date: | 2017-07-18 | Release date: | 2018-04-18 | Last modified: | 2018-05-09 | Method: | X-RAY DIFFRACTION (4.6 Å) | Cite: | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly. Nat Commun, 9, 2018
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5OI9
| Trichoplax adhaerens STIL N-terminal domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative uncharacterized protein | Authors: | van Breugel, M. | Deposit date: | 2017-07-18 | Release date: | 2018-04-18 | Last modified: | 2018-05-09 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly. Nat Commun, 9, 2018
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5OI7
| Human CEP85 - coiled coil domain 4 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal protein of 85 kDa | Authors: | van Breugel, M. | Deposit date: | 2017-07-18 | Release date: | 2018-04-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly. Nat Commun, 9, 2018
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7EN7
| The crystal structure of Escherichia coli MurR in complex with N-acetylmuramic-acid-6-phosphate | Descriptor: | (2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, HTH-type transcriptional regulator MurR | Authors: | Zhang, Y, Chen, W, Ji, Q. | Deposit date: | 2021-04-16 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli. Nucleic Acids Res., 50, 2022
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7EN5
| The crystal structure of Escherichia coli MurR in complex with N-acetylglucosamine-6-phosphate | Descriptor: | 2-METHOXYETHANOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Zhang, Y, Chen, W, Ji, Q. | Deposit date: | 2021-04-16 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli. Nucleic Acids Res., 50, 2022
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7EN6
| The crystal structure of Escherichia coli MurR in apo form | Descriptor: | HTH-type transcriptional regulator MurR, PHOSPHATE ION | Authors: | Zhang, Y, Chen, W, Ji, Q. | Deposit date: | 2021-04-16 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.276 Å) | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli. Nucleic Acids Res., 50, 2022
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7X4E
| Structure of 10635-DndE | Descriptor: | DNA sulfur modification protein DndE, GLYCEROL | Authors: | Haiyan, G, Wei, H, Chen, S, Wang, L, Wu, G. | Deposit date: | 2022-03-02 | Release date: | 2022-04-20 | Last modified: | 2022-07-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635. Mbio, 13, 2022
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3CGL
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1QNK
| TRUNCATED HUMAN GROB[5-73], NMR, 20 STRUCTURES | Descriptor: | C-X-C motif chemokine 2 | Authors: | Qian, Y.Q, Johanson, K, McDevitt, P. | Deposit date: | 1999-10-18 | Release date: | 2000-02-04 | Last modified: | 2018-06-13 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance solution structure of truncated human GRObeta [5-73] and its structural comparison with CXC chemokine family members GROalpha and IL-8. J. Mol. Biol., 294, 1999
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3GMR
| Structure of mouse CD1d in complex with C8Ph, different space group | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... | Authors: | Schiefner, A, Wilson, I.A. | Deposit date: | 2009-03-14 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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3GMM
| Structure of mouse CD1d in complex with C8Ph | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... | Authors: | Schiefner, A, Wilson, I.A. | Deposit date: | 2009-03-14 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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5E3T
| Crystal structure of phosphatidylinositol-4-phosphate 5-kinase | Descriptor: | MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol-4-phosphate 5-kinase, ... | Authors: | Muftuoglu, Y. | Deposit date: | 2015-10-04 | Release date: | 2016-07-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Mechanism of substrate specificity of phosphatidylinositol phosphate kinases. Proc.Natl.Acad.Sci.USA, 113, 2016
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3GMQ
| Structure of mouse CD1d expressed in SF9 cells, no ligand added | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... | Authors: | Schiefner, A, Wilson, I.A. | Deposit date: | 2009-03-14 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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3GMO
| Structure of mouse CD1d in complex with C8PhF | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-(4-fluorophenyl)-N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl}octanamide, ... | Authors: | Schiefner, A, Wilson, I.A. | Deposit date: | 2009-03-14 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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3GZN
| Structure of NEDD8-activating enzyme in complex with NEDD8 and MLN4924 | Descriptor: | NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ... | Authors: | Sintchak, M.D. | Deposit date: | 2009-04-07 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ. Mol.Cell, 37, 2010
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3GMP
| Structure of mouse CD1d in complex with PBS-25 | Descriptor: | (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Schiefner, A, Wilson, I.A. | Deposit date: | 2009-03-14 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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5E3S
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3GMN
| Structure of mouse CD1d in complex with C10Ph | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... | Authors: | Schiefner, A, Wilson, I.A. | Deposit date: | 2009-03-14 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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3GML
| Structure of mouse CD1d in complex with C6Ph | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... | Authors: | Schiefner, A, Wilson, I.A. | Deposit date: | 2009-03-14 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
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5E3U
| Crystal structure of phosphatidylinositol-4-phosphate 5-kinase | Descriptor: | MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol-4-phosphate 5-kinase, ... | Authors: | Muftuoglu, Y. | Deposit date: | 2015-10-04 | Release date: | 2016-07-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Mechanism of substrate specificity of phosphatidylinositol phosphate kinases. Proc.Natl.Acad.Sci.USA, 113, 2016
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3KDH
| Structure of ligand-free PYL2 | Descriptor: | Putative uncharacterized protein At2g26040 | Authors: | Yin, P, Fan, H, Hao, Q, Yuan, X, Yan, N. | Deposit date: | 2009-10-22 | Release date: | 2009-11-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.653 Å) | Cite: | Structural insights into the mechanism of abscisic acid signaling by PYL proteins Nat.Struct.Mol.Biol., 16, 2009
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3KDJ
| Complex structure of (+)-ABA-bound PYL1 and ABI1 | Descriptor: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, MANGANESE (II) ION, Protein phosphatase 2C 56, ... | Authors: | Yin, P, Fan, H, Hao, Q, Yuan, X, Yan, N. | Deposit date: | 2009-10-23 | Release date: | 2009-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.878 Å) | Cite: | Structural insights into the mechanism of abscisic acid signaling by PYL proteins Nat.Struct.Mol.Biol., 16, 2009
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3KDI
| Structure of (+)-ABA bound PYL2 | Descriptor: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Putative uncharacterized protein At2g26040 | Authors: | Yin, P, Fan, H, Hao, Q, Yuan, X, Yan, N. | Deposit date: | 2009-10-22 | Release date: | 2009-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.379 Å) | Cite: | Structural insights into the mechanism of abscisic acid signaling by PYL proteins Nat.Struct.Mol.Biol., 16, 2009
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6I3V
| x-ray structure of the human mitochondrial PRELID1 in complex with TRIAP1 | Descriptor: | CHLORIDE ION, MYRISTIC ACID, PRELI domain-containing protein 1, ... | Authors: | Berry, J.L, Miliara, X, Morgan, R.M.L, Matthews, S.J. | Deposit date: | 2018-11-07 | Release date: | 2019-03-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun, 10, 2019
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